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Select item 70463031.

Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation

Lei Zhang, Yi Wang, Guorao Wu, Lizong Rao, Yanqiu Wei, Huihui Yue, Ting Yuan, Ping Yang, Fei Xiong, Shu Zhang, Qing Zhou, Zhishui Chen, Jinxiu Li, Bi‐Wen Mo, Huilan Zhang, Weining Xiong, Cong‐Yi Wang

Cell Prolif. 2020 Feb; 53(2): e12742. Published online 2020 Jan 14. doi: 10.1111/cpr.12742

PMCID:: PMC7046303

Abstract Article PDF–1.6M

Select item 69768572.

Clinical and Hematological Relevance of JAK2V617F, CALR, and MPL Mutations in Vietnamese Patients with Essential Thrombocythemia

Hoang Anh Vu, Tran Thi Thao, Cao Van Dong, Nguyen Lam Vuong, Ho Quoc Chuong, Phan Nguyen Thanh Van, Huynh Nghia, Nguyen Tan Binh, Phu Chi Dung, Phan Thi Xinh

Asian Pac J Cancer Prev. 2019; 20(9): 2775–2780. doi: 10.31557/APJCP.2019.20.9.2775

PMCID:: PMC6976857

Abstract Article PDF–404K

Select item 67865613.

A conditional inducible JAK2^V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression

Emilie A. Chapeau, Emeline Mandon, Jason Gill, Vincent Romanet, Nicolas Ebel, Violetta Powajbo, Rita Andraos-Rey, Zhiyan Qian, Miltos Kininis, Sabine Zumstein-Mecker, Moriko Ito, Nancy E. Hynes, Ralph Tiedt, Francesco Hofmann, Leonid Eshkind, Ernesto Bockamp, Bernd Kinzel, Matthias Mueller, Masato Murakami, Fabienne Baffert, Thomas Radimerski

PLoS One. 2019; 14(10): e0221635. Published online 2019 Oct 10. doi: 10.1371/journal.pone.0221635

PMCID:: PMC6786561

Abstract Article PDF–3.7M

Select item 21922574.

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

J Exp Med. 1995 Dec 1; 182(6): 1801–1806. doi: 10.1084/jem.182.6.1801

PMCID:: PMC2192257

Summary PDF–688K

Select item 3598935.

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

A F Wilks, A G Harpur, R R Kurban, S J Ralph, G Zürcher, A Ziemiecki

Mol Cell Biol. 1991 Apr; 11(4): 2057–2065. doi: 10.1128/mcb.11.4.2057

PMCID:: PMC359893

Summary Page Browse PDF–2.0M

Select item 65961876.

An Image-Based miRNA Screen Identifies miRNA-135s As Regulators of CNS Axon Growth and Regeneration by Targeting Krüppel-like Factor 4

Eljo Y. van Battum, Marieke G. Verhagen, Vamshidhar R. Vangoor, Yuki Fujita, Alwin A.H.A. Derijck, Eoghan O'Duibhir, Giuliano Giuliani, Thijs de Gunst, Youri Adolfs, Daphne Lelieveld, David Egan, Roel Q.J. Schaapveld, Toshihide Yamashita, R. Jeroen Pasterkamp

J Neurosci. 2018 Jan 17; 38(3): 613–630. doi: 10.1523/JNEUROSCI.0662-17.2017

PMCID:: PMC6596187

Abstract Article PDF–4.2M

Select item 63654907.

Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia

Nicholas C. P. Cross, Yvette Hoade, William J. Tapper, Gonzalo Carreno-Tarragona, Tiziana Fanelli, Mohamad Jawhar, Nicole Naumann, Iwo Pieniak, Johannes Lübke, Sahra Ali, Kaljit Bhuller, Sonja Burgstaller, Catherine Cargo, Jamie Cavenagh, Andrew S. Duncombe, Emma Das-Gupta, Paul Evans, Peter Forsyth, Philip George, Charlotte Grimley, Fergus Jack, Laura Munro, Varun Mehra, Kavita Patel, Ali Rismani, Gabriela Sciuccati, Rowena Thomas-Dewing, Patrick Thornton, Andres Virchis, Simon Watt, Louise Wallis, Alastair Whiteway, Kris Zegocki, Barbara J. Bain, Andreas Reiter, Andrew Chase

Leukemia. 2019; 33(2): 415–425. Published online 2018 Dec 20. doi: 10.1038/s41375-018-0342-3

PMCID:: PMC6365490

Abstract Article PDF–1.5M

Select item 58439978.

Sequencing of circulating tumor DNA for dynamic monitoring of gene mutations in advanced non-small cell lung cancer

Ruilian Xu, Guolin Zhong, Tanxiao Huang, Wan He, Cheng Kong, Xiaoni Zhang, Ying Wang, Ming Liu, Mingyan Xu, Shifu Chen

Oncol Lett. 2018 Mar; 15(3): 3726–3734. Published online 2018 Jan 16. doi: 10.3892/ol.2018.7808

PMCID:: PMC5843997

Abstract Article PDF–1.5M

Select item 58008869.

Regulation of Oxidative Stress in Pulmonary Artery Endothelium. Modulation of Extracellular Superoxide Dismutase and NOX4 Expression Using Histone Deacetylase Class I Inhibitors

Igor N. Zelko, Rodney J. Folz

Am J Respir Cell Mol Biol. 2015 Oct; 53(4): 513–524. doi: 10.1165/rcmb.2014-0260OC

PMCID:: PMC5800886

Abstract Article PDF–1.0M

Select item 573276510.

Fusion of the genes ataxin 2 like, ATXN2L, and Janus kinase 2, JAK2, in cutaneous CD4 positive T-cell lymphoma

Ioannis Panagopoulos, Ludmila Gorunova, Signe Spetalen, Assia Bassarova, Klaus Beiske, Francesca Micci, Sverre Heim

Oncotarget. 2017 Nov 28; 8(61): 103775–103784. Published online 2017 Oct 10. doi: 10.18632/oncotarget.21790

PMCID:: PMC5732765

Abstract Article PDF–3.3M

Select item 570718511.

Detection of Mutations in Myeloid Malignancies through Paired-Sample Analysis of Microdroplet-PCR Deep Sequencing Data

Donavan T. Cheng, Janice Cheng, Talia N. Mitchell, Aijazuddin Syed, Ahmet Zehir, Nana Yaa T. Mensah, Alifya Oultache, Khedoudja Nafa, Ross L. Levine, Maria E. Arcila, Michael F. Berger, Cyrus V. Hedvat

J Mol Diagn. 2014 Sep; 16(5): 504–518. doi: 10.1016/j.jmoldx.2014.05.006

PMCID:: PMC5707185

Abstract Article PDF–1.3M

Select item 565186112.

Identification of differentially expressed circular RNAs in human monocyte derived macrophages response to Mycobacterium tuberculosis infection

Zikun Huang, Rigu Su, Zhen Deng, Jianqing Xu, Yiping Peng, Qing Luo, Junming Li

Sci Rep. 2017; 7: 13673. Published online 2017 Oct 20. doi: 10.1038/s41598-017-13885-0

PMCID:: PMC5651861

Abstract Article PDF–2.0M

Select item 510113213.

Upregulation of Interferon-inducible and damage response pathways in chronic graft-versus-host disease

Frances T. Hakim, Sarfraz Memon, Ping Jin, Matin M. Imanguli, Huan Wang, Najibah Rehman, Xiao-Yi Yan, Jeremy Rose, Jacqueline W. Mays, Susan Dhamala, Veena Kapoor, William Telford, John Dickinson, Sean Davis, David Halverson, Haley B. Naik, Kristin Baird, Daniel Fowler, David Stroncek, Edward W. Cowen, Steven Z. Pavletic, Ronald E. Gress

J Immunol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: J Immunol. 2016 Nov 1; 197(9): 3490–3503. Published online 2016 Sep 30. doi: 10.4049/jimmunol.1601054

PMCID:: PMC5101132

Abstract Article PDF–1.8M

Select item 491479614.

Dose- and Time-Dependent Transcriptional Response of Ishikawa Cells Exposed to Genistein

Jorge M. Naciff, Zubin S. Khambatta, Gregory J. Carr, Jay P. Tiesman, David W. Singleton, Sohaib A. Khan, George P. Daston

Toxicol Sci. 2016 May; 151(1): 71–87. Published online 2016 Feb 10. doi: 10.1093/toxsci/kfw024

PMCID:: PMC4914796

Abstract Article PDF–285K

Select item 415209415.

Absence of 19 known hotspot oncogenic mutations in soft tissue clear cell sarcoma: two cases report with review of the literature

Chunxia Liu, Yan Ren, Xiaoying Li, Yuwen Cao, Yunzhao Chen, Xiaobin Cui, Li Li, Feng Li

Int J Clin Exp Pathol. 2014; 7(8): 5242–5249. Published online 2014 Jul 15.

PMCID:: PMC4152094

Abstract Article PDF–1.2M

Select item 412342016.

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

Andrew N. Harman, Joey Lai, Stuart Turville, Shamith Samarajiwa, Lachlan Gray, Valerie Marsden, Sarah Mercier, Kate Jones, Najla Nasr, Arjun Rustagi, Helen Cumming, Heather Donaghy, Johnson Mak, Michael Gale, Jr, Melissa Churchill, Paul Hertzog, Anthony L. Cunningham

Blood. 2011 Jul 14; 118(2): 298–308. Prepublished online 2011 Mar 16. doi: 10.1182/blood-2010-07-297721

Correction in:: Blood. 2011 Dec 22; 118(26): 6992.

PMCID:: PMC4123420

Abstract Article

Select item 383451617.

Differential Gene Expression Analysis in K562 Human Leukemia Cell Line Treated with Benzene

Sulji Choi, Ji-Young Kim, Jai-Dong Moon, Hee Jo Baek, Hoon Kook, Sang-Beom Seo

Toxicol Res. 2011 Mar; 27(1): 43–48. doi: 10.5487/TR.2011.27.1.043

PMCID:: PMC3834516

Abstract Article PDF–1.7M

Select item 372811918.

Design and application of a novel PNA probe for the detection at single cell level of JAK2^V617F mutation in Myeloproliferative Neoplasms

Enrico Bracco, Valentina Rosso, Anna Serra, Francesca Carnuccio, Valentina Gaidano, Paolo Nicoli, Pellegrino Musto, Giuseppe Saglio, Francesco Frassoni, Daniela Cilloni

BMC Cancer. 2013; 13: 348. Published online 2013 Jul 18. doi: 10.1186/1471-2407-13-348

PMCID:: PMC3728119

Abstract Article PDF–511K

Select item 362430919.

MicroRNA-27a Regulates Lipid Metabolism and Inhibits Hepatitis C Virus Replication in Human Hepatoma Cells

Takayoshi Shirasaki, Masao Honda, Tetsuro Shimakami, Rika Horii, Taro Yamashita, Yoshio Sakai, Akito Sakai, Hikari Okada, Risa Watanabe, Seishi Murakami, MinKyung Yi, Stanley M. Lemon, Shuichi Kaneko

J Virol. 2013 May; 87(9): 5270–5286. doi: 10.1128/JVI.03022-12

PMCID:: PMC3624309

Abstract Article PDF–4.9M

Select item 355311220.

t(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 via STAT5

Stefan Ehrentraut, Stefan Nagel, Michaela E. Scherr, Björn Schneider, Hilmar Quentmeier, Robert Geffers, Maren Kaufmann, Corinna Meyer, Monika Prochorec-Sobieszek, Rhett P. Ketterling, Ryan A. Knudson, Andrew L. Feldman, Marshall E. Kadin, Hans G. Drexler, Roderick A. F. MacLeod

PLoS One. 2013; 8(1): e53767. Published online 2013 Jan 23. doi: 10.1371/journal.pone.0053767

PMCID:: PMC3553112

Abstract Article PDF–1.6M

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