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Select item 106872011.

High cell-free DNA is associated with disease progression, inflammasome activation and elevated levels of inflammasome-related cytokine IL-18 in patients with myelofibrosis

Geraldine De Luca, Paola R. Lev, Maria F. Camacho, Nora P. Goette, Federico Sackmann, Miguel A. Castro Ríos, Beatriz Moiraghi, Veronica Cortes Guerrieri, Georgina Bendek, Emiliano Carricondo, Alicia Enrico, Veronica Vallejo, Ana Varela, Marina Khoury, Marina Gutierrez, Irene B. Larripa, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller

Front Immunol. 2023; 14: 1161832. Published online 2023 Nov 16. doi: 10.3389/fimmu.2023.1161832

PMCID:: PMC10687201

Abstract Article PDF–3.0M

Select item 106517662.

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy

Annatina S. Schnegg-Kaufmann, Julie A. I. Thoms, Golam Sarower Bhuyan, Henry R. Hampton, Lachlin Vaughan, Kayleigh Rutherford, Purvi M. Kakadia, Hui Mei Lee, Emma M. V. Johansson, Timothy W. Failes, Greg M. Arndt, Jason Koval, Robert Lindeman, Pauline Warburton, Alba Rodriguez-Meira, Adam J. Mead, Ashwin Unnikrishnan, Sarah Davidson, Mark N. Polizzotto, Mark Hertzberg, Elli Papaemmanuil, Stefan K. Bohlander, Omid R. Faridani, Christopher J. Jolly, Fabio Zanini, John E. Pimanda

Blood. 2023 Mar 16; 141(11): 1316–1321. Published online 2022 Dec 12. doi: 10.1182/blood.2022018602

PMCID:: PMC10651766

Abstract Article

Select item 104451243.

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice

Joshua H. Bourne, Joana Campos, Sophie J. Hopkin, Katharine Whitworth, James Palis, Yotis A. Senis, Julie Rayes, Asif J. Iqbal, Alexander Brill

Front Immunol. 2023; 14: 1226196. Published online 2023 Aug 9. doi: 10.3389/fimmu.2023.1226196

PMCID:: PMC10445124

Abstract Article PDF–1.6M

Select item 104296534.

Fusobacterium nucleatum Promotes Megakaryocyte Maturation in Patients with Gastric Cancer via Inducing the Production of Extracellular Vesicles Containing 14-3-3ε

Chang Liu, He Zhang, Tiepeng Li, Zhiqiang Jiang, Yiqiang Yuan, Xiaobing Chen

Infect Immun. 2023 Aug; 91(8): e00102-23. Published online 2023 Jul 5. doi: 10.1128/iai.00102-23

PMCID:: PMC10429653

Abstract Article PDF–2.1M

Select item 103732585.

Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis

Wenjing Lei, Zhuoliang Liu, Zhiyuan Su, Panpan Meng, Chun Zhou, Xiaomei Chen, Zheng Hu, An Xiao, Miaomiao Zhou, Liping Huang, Yiyue Zhang, Xianhui Qin, Junping Wang, Fengxin Zhu, Jing Nie

J Hematol Oncol. 2023; 16: 84. Published online 2023 Jul 27. doi: 10.1186/s13045-023-01481-x

PMCID:: PMC10373258

Abstract Article PDF–5.3M

Select item 103329816.

Focal Segmental Glomerulosclerosis Associated with Essential Thrombocythemia

Hisashi Sugimoto, Naoki Sawa, Hajime Yamagiwa, Masahiro Kawada, Daisuke Ikuma, Yuki Oba, Hiroki Mizuno, Akinari Sekine, Masayuki Yamanouchi, Eiko Hasegawa, Tatsuya Suwabe, Aya Nishida, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Yutaka Yamaguchi, Yoshifumi Ubara

Intern Med. 2023 Jun 15; 62(12): 1789–1794. Published online 2022 Oct 26. doi: 10.2169/internalmedicine.0767-22

PMCID:: PMC10332981

Abstract Article PDF–1.2M

Select item 101535277.

Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia

Valeria Capaci, Etai Adam, Ifat Bar-Joseph, Michela Faleschini, Alessandro Pecci, Anna Savoia

Haematologica. 2023 May 1; 108(5): 1385–1393. Published online 2022 Oct 13. doi: 10.3324/haematol.2022.281392

PMCID:: PMC10153527

Abstract Article PDF–1.3M

Select item 101398668.

Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels

Amanda E. Au, Jason Corbin, Marion Lebois, Pradnya Gangatirkar, Fatme Yassinson, Stephanie R. Hyslop, Ping Cannon, Kylie D. Mason, Connie S. N. Li-Wai-Suen, Alexandra L. Garnham, Diane Moujalled, Luisa Cimmino, Warren S. Alexander, Emma C. Josefsson

Blood Adv. 2023 Apr 25; 7(8): 1560–1571. Published online 2022 Sep 9. doi: 10.1182/bloodadvances.2022007849

PMCID:: PMC10139866

Abstract Article PDF–1.0M

Select item 98135349.

Treatment of congenital thrombocytopenia and decreased collagen reactivity in G6b-B–deficient mice

Alexandra Mazharian, Blandine Maître, Alicia Bornert, Desline Hennequin, Marc Lourenco-Rodrigues, Mitchell J. Geer, Christopher W. Smith, Silke Heising, Michaela Walter, Florian Montel, Lucy S. K. Walker, Henri de la Salle, Steve P. Watson, Christian Gachet, Yotis A. Senis

Blood Adv. 2023 Jan 10; 7(1): 46–59. Published online 2022 Oct 27. doi: 10.1182/bloodadvances.2022008873

PMCID:: PMC9813534

Abstract Article PDF–1.5M

Select item 980021410.

阻断PAK1激酶活性对急性巨核细胞白血病细胞分化及凋亡的影响

王淑瑾, 王春晴, 胡雪婷, 于翔茹, 付春玲

Zhonghua Xue Ye Xue Za Zhi. 2022 Jun; 43(6): 499–505. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2022.06.010

PMCID:: PMC9800214

Abstract Article PDF–1.3M

Select item 968841411.

JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network

Jialing Wang, Xiaodan Liu, Haixia Wang, Lili Qin, Anhua Feng, Daoxin Qi, Haihua Wang, Yao Zhao, Lihua Kong, Haiying Wang, Lin Wang, Zhenbo Hu, Xin Xu

Cells. 2022 Nov; 11(22): 3660. Published online 2022 Nov 18. doi: 10.3390/cells11223660

PMCID:: PMC9688414

Abstract Article PDF–3.2M

Select item 967044012.

A case of ischemic stroke with hemorrhagic transformation associated with essential thrombocythemia and JAK-2 V617F mutation

Ran Yan, Donghua Mi, Xin Qiu, Zixiao Li

BMC Neurol. 2022; 22: 437. Published online 2022 Nov 17. doi: 10.1186/s12883-022-02964-z

PMCID:: PMC9670440

Abstract Article PDF–981K

Select item 963166313.

Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans

Dmitri V. Gnatenko, Zhaoyan Liu, Patrick Hearing, Sook-Young Sohn, Yetao Hu, Anna Falanga, Song Wu, Lisa E. Malone, Wei Zhu, Wadie F. Bahou

Blood Adv. 2022 Aug 23; 6(16): 4884–4900. Published online 2022 Aug 22. doi: 10.1182/bloodadvances.2021005648

PMCID:: PMC9631663

Abstract Article PDF–2.4M

Select item 963164514.

Verónica Palma-Barqueros, Nuria Revilla, Carlo Zaninetti, Ana María Galera, Ana Sánchez-Fuentes, Ana Zámora-Cánovas, Natalia Bohdan, José Padilla, Ana Marín-Quilez, Agustín Rodriguez-Alen, José Luis Fuster, Andreas Greinacher, Vicente Vicente, José María Bastida, José Rivera, María Luisa Lozano

Blood Adv. 2022 Sep 13; 6(17): 5244–5255. Published online 2022 Sep 12. doi: 10.1182/bloodadvances.2021005446

PMCID:: PMC9631645

Abstract Article PDF–1.7M

Select item 942532215.

The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse

Sachiko Kanaji, Yosuke Morodomi, Hartmut Weiler, Alessandro Zarpellon, Robert R. Montgomery, Zaverio M. Ruggeri, Taisuke Kanaji

Haematologica. 2022 Sep 1; 107(9): 2133–2143. Published online 2022 Feb 10. doi: 10.3324/haematol.2021.280561

PMCID:: PMC9425322

Abstract Article PDF–1.9M

Select item 919759316.

Characterization of the Role of Integrin α5β1 in Platelet Function, Hemostasis, and Experimental Thrombosis

Emily Janus-Bell, Alexandra Yakusheva, Cyril Scandola, Nicolas Receveur, Usman Muhammad Ahmed, Clarisse Mouriaux, Catherine Bourdon, Cécile Loubière, Anita Eckly, Yotis A. Senis, Mikhail A. Panteleev, Christian Gachet, Pierre H. Mangin

Thromb Haemost. 2022 May; 122(5): 767–776. Published online 2021 Nov 10. doi: 10.1055/a-1659-6214

PMCID:: PMC9197593

Abstract Article PDF–3.0M

Select item 821164217.

M2 macrophages, but not M1 macrophages, support megakaryopoiesis by upregulating PI3K-AKT pathway activity

Hong-Yan Zhao, Yuan-Yuan Zhang, Tong Xing, Shu-Qian Tang, Qi Wen, Zhong-Shi Lyu, Meng Lv, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Yuan Kong, Xiao-Jun Huang

Signal Transduct Target Ther. 2021; 6: 234. Published online 2021 Jun 18. doi: 10.1038/s41392-021-00627-y

PMCID:: PMC8211642

Abstract Article PDF–6.4M

Select item 819059618.

Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model

Sara Borst, Catriana C. Nations, Joshua G. Klein, Giulia Pavani, Jean Ann Maguire, Rodney M. Camire, Michael W. Drazer, Lucy A. Godley, Deborah L. French, Mortimer Poncz, Paul Gadue

Stem Cell Reports. 2021 Jun 8; 16(6): 1458–1467. Published online 2021 May 20. doi: 10.1016/j.stemcr.2021.04.013

PMCID:: PMC8190596

Abstract Article PDF–2.2M

Select item 801122619.

Myeloproliferative neoplasm-driving Calr frameshift promotes the development of pulmonary hypertension in mice

Keiji Minakawa, Tetsuro Yokokawa, Koki Ueda, Osamu Nakajima, Tomofumi Misaka, Yusuke Kimishima, Kento Wada, Yusuke Tomita, Saori Miura, Yuka Sato, Kosaku Mimura, Koichi Sugimoto, Kazuhiko Nakazato, Kenneth E. Nollet, Kazuei Ogawa, Takayuki Ikezoe, Yuko Hashimoto, Yasuchika Takeishi, Kazuhiko Ikeda

J Hematol Oncol. 2021; 14: 52. Published online 2021 Mar 30. doi: 10.1186/s13045-021-01064-8

PMCID:: PMC8011226

Abstract Article PDF–1.0M

Select item 797831120.

Aurka loss in CD19⁺ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production

Xin Chen, Chennan Wang, Na Sun, Shuai Pan, Rongqing Li, Xueqin Li, Jie Zhao, Huan Tong, Yangyang Tang, Jing Han, Jianlin Qiao, Hongbin Qiu, Hui Wang, Jing Yang, Takayuki Ikezoe

Theranostics. 2021; 11(10): 4655–4671. Published online 2021 Mar 4. doi: 10.7150/thno.49007

PMCID:: PMC7978311

Abstract Article PDF–2.3M

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PMC Articles for MedGen (Select 870733) (108)
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PREDICTED: Homo sapiens huntingtin interacting protein 1 (HIP1), transcript vari...
PREDICTED: Homo sapiens huntingtin interacting protein 1 (HIP1), transcript variant X1, mRNA
gi|2462613979|ref|XM_054358039.1|

Nucleotide
CCDC144NL-AS1 CCDC144NL antisense RNA 1 [Homo sapiens]
CCDC144NL-AS1 CCDC144NL antisense RNA 1 [Homo sapiens]
Gene ID:440416

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Gene Links for GEO Profiles (Select 115439624) (1)
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Chromosome neighbors for GEO Profiles (Select 93656110) (20)
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