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Select item 101181901.

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro

Daniel Koch, Ay Lin Kho, Atsushi Fukuzawa, Alexander Alexandrovich, Kutti J. Vanaanen, Andrew Beavil, Mark Pfuhl, Martin Rees, Mathias Gautel

PLoS One. 2023; 18(4): e0284453. Published online 2023 Apr 20. doi: 10.1371/journal.pone.0284453

PMCID:: PMC10118190

Article PDF–2.6M

Select item 68645902.

Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex

Andreas Gerondopoulos, Helen Strutt, Nicola L. Stevenson, Tomoaki Sobajima, Tim P. Levine, David J. Stephens, David Strutt, Francis A. Barr

Curr Biol. 2019 Oct 7; 29(19): 3323–3330.e8. doi: 10.1016/j.cub.2019.07.090

PMCID:: PMC6864590

Article

Select item 64592803.

Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy

Manish Mishra, Arul J. Duraisamy, Sudarshan Bhattacharjee, Renu A. Kowluru

Antioxid Redox Signal. 2019 May 1; 30(13): 1621–1634. Published online 2019 Mar 19. doi: 10.1089/ars.2018.7542

PMCID:: PMC6459280

Article PDF–1.0M

Select item 51322614.

Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone Proteins Piccolo and Bassoon

Ryan T. Terry-Lorenzo, Viviana I. Torres, Dhananjay Wagh, Jose Galaz, Selene K. Swanson, Laurence Florens, Michael P. Washburn, Clarissa L. Waites, Eckart D. Gundelfinger, Richard J. Reimer, Craig C. Garner

PLoS One. 2016; 11(12): e0167535. Published online 2016 Dec 1. doi: 10.1371/journal.pone.0167535

PMCID:: PMC5132261

Article PDF–3.2M

Select item 31292155.

Characterization of RIN3 as a Guanine Nucleotide Exchange Factor for the Rab5 Subfamily GTPase Rab31

Hiroaki Kajiho, Kyoko Sakurai, Tomohiro Minoda, Manabu Yoshikawa, Satoshi Nakagawa, Shinichi Fukushima, Kenji Kontani, Toshiaki Katada

J Biol Chem. 2011 Jul 8; 286(27): 24364–24373. Published online 2011 May 17. doi: 10.1074/jbc.M110.172445

PMCID:: PMC3129215

Article PDF–3.4M

Select item 30335176.

Mutations and Deletions in PCDH19 Account for Various Familial or Isolated Epilepsies in Females

Christel Depienne, Oriane Trouillard, Delphine Bouteiller, Isabelle Gourfinkel-An, Karine Poirier, François Rivier, Patrick Berquin, Rima Nabbout, Denys Chaigne, Dominique Steschenko, Agnès Gautier, Dorota Hoffman-Zacharska, Annie Lannuzel, Marilyn Lackmy-Port-Lis, Hélène Maurey, Anne Dusser, Marie Bru, Brigitte Gilbert-Dussardier, Agathe Roubertie, Anna Kaminska, Sandra Whalen, Cyril Mignot, Stéphanie Baulac, Gaetan Lesca, Alexis Arzimanoglou, Eric LeGuern

Hum Mutat. 2011 Jan; 32(1): E1959–E1975. doi: 10.1002/humu.21373

PMCID:: PMC3033517

Article PDF–577K

Select item 26937267.

Co-activation of G-Protein Signaling by Cell-Surface Receptors and an Intracellular Exchange-Factor

Michael J. Lee, Henrik G. Dohlman

Curr Biol. Author manuscript; available in PMC 2009 Jun 9.

Published in final edited form as: Curr Biol. 2008 Feb 12; 18(3): 211–215. doi: 10.1016/j.cub.2008.01.007

PMCID:: PMC2693726

Article PDF–697K

Select item 157688.

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia

Peter J. Kourlas, Matthew P. Strout, Brian Becknell, Maria Luisa Veronese, Carlo M. Croce, Karl S. Theil, Ralf Krahe, Tapani Ruutu, Sakari Knuutila, Clara D. Bloomfield, Michael A. Caligiuri

Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5): 2145–2150. Published online 2000 Feb 11. doi: 10.1073/pnas.040569197

PMCID:: PMC15768

Article PDF–213K

Select item 98463779.

Outcomes of Candida and Non-Candida Aortic Graft Infection

Safwan Omran, Steffen Gröger, Bashaer Shafei, Larissa Schawe, Leon Bruder, Haidar Haidar, Andreas Greiner

Vasc Endovascular Surg. 2023 Feb; 57(2): 97–105. Published online 2022 Sep 23. doi: 10.1177/15385744221129236

PMCID:: PMC9846377

Article PDF–864K

Select item 942170610.

Genetic Landscape of SCN1A Variants in a Turkish Cohort with GEFS+ Spectrum and Dravet Syndrome

Ayberk Türkyılmaz, Emine Tekin, Oğuzhan Yaralı, Alper Han Çebi

Mol Syndromol. 2022 Jul; 13(4): 270–281. Published online 2022 Feb 22. doi: 10.1159/000521330

PMCID:: PMC9421706

Article PDF–198K

Select item 931564911.

Integrating Activity-Guided Strategy and Fingerprint Analysis to Target Potent Cytotoxic Brefeldin A from a Fungal Library of the Medicinal Mangrove Acanthus ilicifolius

Cui-Fang Wang, Jie Ma, Qian-Qian Jing, Xi-Zhen Cao, Lu Chen, Rong Chao, Ji-Yong Zheng, Chang-Lun Shao, Xiao-Xi He, Mei-Yan Wei

Mar Drugs. 2022 Jul; 20(7): 432. Published online 2022 Jun 29. doi: 10.3390/md20070432

PMCID:: PMC9315649

Article PDF–2.8M

Select item 334030112.

Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells

Miguel A Mendoza-Catalán, Gema R Cristóbal-Mondragón, Jesús Adame-Gómez, Heidi N del Valle-Flores, José Fco Coppe, Laura Sierra-López, Mirna A Romero-Hernández, Luz del Carmen Alarcón-Romero, Berenice Illades-Aguiar, Eduardo Castañeda-Saucedo

BMC Cancer. 2012; 12: 116. Published online 2012 Mar 23. doi: 10.1186/1471-2407-12-116

PMCID:: PMC3340301

Article PDF–1.7M

Select item 1072414113.

Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles

Suchet Nanda, Abram Calderon, Arya Sachan, Thanh-Thuy Duong, Johannes Koch, Xiaoyi Xin, Djamschid Solouk-Stahlberg, Yao-Wen Wu, Perihan Nalbant, Leif Dehmelt

Nat Commun. 2023; 14: 8356. Published online 2023 Dec 15. doi: 10.1038/s41467-023-43875-y

PMCID:: PMC10724141

Article PDF–7.0M

Select item 983366414.

Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement

Robert A. Law, Alexander Kiepas, Habben E. Desta, Emiliano Perez Ipiña, Maria Parlani, Se Jong Lee, Christopher L. Yankaskas, Runchen Zhao, Panagiotis Mistriotis, Nianchao Wang, Zhizhan Gu, Petr Kalab, Peter Friedl, Brian A. Camley, Konstantinos Konstantopoulos

Sci Adv. 2023 Jan; 9(2): eabq6480. Published online 2023 Jan 11. doi: 10.1126/sciadv.abq6480

PMCID:: PMC9833664

Article PDF–1.8M

Select item 932298715.

Phenotypic and Genotypic Spectrum of Early-Onset Developmental and Epileptic Encephalopathies—Data from a Romanian Cohort

Anca-Lelia Riza, Ioana Streață, Eugenia Roza, Magdalena Budișteanu, Catrinel Iliescu, Carmen Burloiu, Mihaela-Amelia Dobrescu, Stefania Dorobanțu, Adina Dragoș, Andra Grigorescu, Tiberiu Tătaru, Mihai Ioana, Raluca Teleanu

Genes (Basel) 2022 Jul; 13(7): 1253. Published online 2022 Jul 15. doi: 10.3390/genes13071253

PMCID:: PMC9322987

Article PDF–315K

Select item 756533616.

Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast

Iker Lamas, Nathalie Weber, Sophie G. Martin

Cells. 2020 Sep; 9(9): 2089. Published online 2020 Sep 12. doi: 10.3390/cells9092089

PMCID:: PMC7565336

Article PDF–2.4M

Select item 722677217.

Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics

Daji Guo, Xiaoman Yang, Lei Shi

Cells. 2020 Apr; 9(4): 835. Published online 2020 Mar 31. doi: 10.3390/cells9040835

PMCID:: PMC7226772

Article PDF–1020K

Select item 671946118.

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

Mihai L. Azoitei, Jungsik Noh, Daniel J. Marston, Philippe Roudot, Christopher B. Marshall, Timothy A. Daugird, Sidney L. Lisanza, María-José Sandí, Mitsu Ikura, John Sondek, Robert Rottapel, Klaus M. Hahn, Gaudenz Danuser

J Cell Biol. 2019 Sep 2; 218(9): 3077–3097. Published online 2019 Aug 16. doi: 10.1083/jcb.201812073

PMCID:: PMC6719461

Article PDF–5.6M

Select item 653971919.

Involvement of BIG5 and BIG3 in BRI1 Trafficking Reveals Diverse Functions of BIG-subfamily ARF-GEFs in Plant Growth and Gravitropism

Shan Xue, Junjie Zou, Yangfan Liu, Ming Wang, Chunxia Zhang, Jie Le

Int J Mol Sci. 2019 May; 20(9): 2339. Published online 2019 May 11. doi: 10.3390/ijms20092339

PMCID:: PMC6539719

Article PDF–3.3M

Select item 543592820.

Rgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast

Elvira Manjón, Tomás Edreira, Sofía Muñoz, Yolanda Sánchez

Nucleic Acids Res. 2017 May 19; 45(9): 5269–5284. Published online 2017 Mar 15. doi: 10.1093/nar/gkx176

PMCID:: PMC5435928

Article PDF–7.7M

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