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Select item 108171281.

Association between ELMO1 gene polymorphisms and diabetic kidney disease: A systematic review and meta-analysis

Alireza Azarboo, Shaghayegh Hosseinkhani, Amirhossein Ghaseminejad-Raeini, Hossein Aazami, Sayed Mohammad Mohammadi, Saba Zeidi, Farideh Razi, Fatemeh Bandarian

PLoS One. 2024; 19(1): e0295607. Published online 2024 Jan 26. doi: 10.1371/journal.pone.0295607

PMCID:: PMC10817128

Article PDF–1.4M

Select item 98996192.

Engulfment and cell motility protein 1 fosters reprogramming of tumor‐associated macrophages in colorectal cancer

Bo Wen, Sheng Li, Lei Ruan, Yanping Yang, Zilin Chen, Bin Zhang, Xin Yang, Haiqing Jie, Shujuan Li, Ziwei Zeng, Sisi Liu

Cancer Sci. 2023 Feb; 114(2): 410–422. Published online 2022 Dec 7. doi: 10.1111/cas.15628

PMCID:: PMC9899619

Article PDF–39M

Select item 65426343.

ELMO1 variants and susceptibility to diabetic nephropathy in American Indians

Robert L. Hanson, Meredith P. Millis, Naomi J. Young, Sayuko Kobes, Robert G. Nelson, William C. Knowler, Johanna K. DiStefano

Mol Genet Metab. Author manuscript; available in PMC 2019 May 30.

Published in final edited form as: Mol Genet Metab. 2010 Dec; 101(4): 383–390. Published online 2010 Aug 19. doi: 10.1016/j.ymgme.2010.08.014

PMCID:: PMC6542634

Article PDF–794K

Select item 46409024.

An Evolutionarily Conserved Autoinhibitory Molecular Switch in ELMO Proteins Regulates Rac Signaling

Manishha Patel, Yoran Margaron, Nadine Fradet, Qi Yang, Brian Wilkes, Michel Bouvier, Kay Hofmann, Jean-François Côté

Curr Biol. Author manuscript; available in PMC 2015 Nov 10.

Published in final edited form as: Curr Biol. 2010 Nov 23; 20(22): 2021–2027. Published online 2010 Oct 28. doi: 10.1016/j.cub.2010.10.028

PMCID:: PMC4640902

Article PDF–1.4M

Select item 42161155.

ELMO1 Is Upregulated in AML CD34+ Stem/Progenitor Cells, Mediates Chemotaxis and Predicts Poor Prognosis in Normal Karyotype AML

Marta E. Capala, Edo Vellenga, Jan Jacob Schuringa

PLoS One. 2014; 9(10): e111568. Published online 2014 Oct 31. doi: 10.1371/journal.pone.0111568

PMCID:: PMC4216115

Article PDF–1.0M

Select item 28673396.

ELMO1 and Dock180, a Bipartite Rac1 Guanine Nucleotide Exchange Factor, Promote Human Glioma Cell Invasion

Michael J. Jarzynka, Bo Hu, Kwok-Min Hui, Ifat Bar-Joseph, Weisong Gu, Takanori Hirose, Lisa B. Haney, Kodi S. Ravichandran, Ryo Nishikawa, Shi-Yuan Cheng

Cancer Res. Author manuscript; available in PMC 2010 May 11.

Published in final edited form as: Cancer Res. 2007 Aug 1; 67(15): 7203–7211. doi: 10.1158/0008-5472.CAN-07-0473

PMCID:: PMC2867339

Article PDF–2.2M

Select item 27780567.

Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans

T. S. Leak, P.S. Perlegas, S.G. Smith, K.L. Keene, P.J. Hicks, C.D. Langefeld, J.C. Mychaleckyj, S.S. Rich, J.K. Kirk, B.I. Freedman, D.W. Bowden, M.M. Sale

Ann Hum Genet. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: Ann Hum Genet. 2009 Mar; 73(2): 152–159. Published online 2009 Jan 23. doi: 10.1111/j.1469-1809.2008.00498.x

PMCID:: PMC2778056

Article PDF–349K

Select item 27681698.

Confirmation of Genetic Associations at ELMO1 in the GoKinD Collection Supports Its Role as a Susceptibility Gene in Diabetic Nephropathy

Marcus G. Pezzolesi, Pisut Katavetin, Masahiko Kure, G. David Poznik, Jan Skupien, Josyf C. Mychaleckyj, Stephen S. Rich, James H. Warram, Andrzej S. Krolewski

Diabetes. 2009 Nov; 58(11): 2698–2702. Published online 2009 Aug 3. doi: 10.2337/db09-0641

PMCID:: PMC2768169

Article PDF–104K

Select item 84331499.

TNF-α-mediated m⁶A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis

Zhongyu Xie, Wenhui Yu, Guan Zheng, Jinteng Li, Shuizhong Cen, Guiwen Ye, Zhaofeng Li, Wenjie Liu, Ming Li, Jiajie Lin, Zepeng Su, Yunshu Che, Feng Ye, Peng Wang, Yanfeng Wu, Huiyong Shen

Nat Commun. 2021; 12: 5373. Published online 2021 Sep 10. doi: 10.1038/s41467-021-25710-4

PMCID:: PMC8433149

Article PDF–3.4M

Select item 808490210.

ELMO1 and APOA1 as Candidate Genes for Sickle Cell Nephropathy

Santosh L. Saraf, Xu Zhang, Binal N. Shah, Rasha Raslan, Bamidele O. Tayo, James P. Lash, Nora Franceschini, Victor R. Gordeuk

Br J Haematol. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Br J Haematol. 2021 May; 193(3): 628–632. Published online 2020 Nov 20. doi: 10.1111/bjh.17224

PMCID:: PMC8084902

Article PDF–672K

Select item 758924611.

The single nucleotide polymorphism rs11643718 in SLC12A3 is associated with the development of diabetic kidney disease in Chinese people with type 2 diabetes

J.‐F. Yang, X.‐F. Xiong, Y. Xiao, L. Wei, L. Li, M. Yang, Y.‐C. Han, H. Zhao, C.‐R. Li, N. Jiang, S. Xiong, L.‐F. Zeng, Z.‐G. Zhou, S.‐P. Liu, N.‐S. Wang, Y. Fan, L. Sun

Diabet Med. 2020 Nov; 37(11): 1879–1889. Published online 2020 Jul 23. doi: 10.1111/dme.14364

PMCID:: PMC7589246

Article PDF–1.7M

Select item 735199912.

Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

Leifu Chang, Jing Yang, Chang Hwa Jo, Andreas Boland, Ziguo Zhang, Stephen H. McLaughlin, Afnan Abu-Thuraia, Ryan C. Killoran, Matthew J. Smith, Jean-Francois Côté, David Barford

Nat Commun. 2020; 11: 3464. Published online 2020 Jul 10. doi: 10.1038/s41467-020-17271-9

PMCID:: PMC7351999

Article PDF–5.8M

Select item 440675013.

Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets

John W. Whitaker, David L. Boyle, Beatrix Bartok, Scott T. Ball, Steffen Gay, Wei Wang, Gary S. Firestein

PLoS One. 2015; 10(4): e0124254. Published online 2015 Apr 22. doi: 10.1371/journal.pone.0124254

Correction in:: PLoS One. 2015; 10(8): e0136334.

PMCID:: PMC4406750

Article PDF–11M

Select item 329531014.

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

Kyoko Hanawa-Suetsugu, Mutsuko Kukimoto-Niino, Chiemi Mishima-Tsumagari, Ryogo Akasaka, Noboru Ohsawa, Shun-ichi Sekine, Takuhiro Ito, Naoya Tochio, Seizo Koshiba, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, Akihiko Nishikimi, Takehito Uruno, Tomoya Katakai, Tatsuo Kinashi, Daisuke Kohda, Yoshinori Fukui, Shigeyuki Yokoyama

Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9): 3305-3310. Published online 2012 Feb 13. doi: 10.1073/pnas.1113512109

PMCID:: PMC3295310

Article PDF–1.7M

Select item 244156815.

Identification of Tyrosine Residues on ELMO1 That Are Phosphorylated by the Src-Family Kinase Hck

Noriko Yokoyama, Colin D. deBakker, Francesca Zappacosta, Michael J. Huddleston, Roland S. Annan, Kodi S. Ravichandran, W. Todd Miller

Biochemistry. Author manuscript; available in PMC 2008 Jun 27.

Published in final edited form as: Biochemistry. 2005 Jun 21; 44(24): 8841–8849. doi: 10.1021/bi0500832

PMCID:: PMC2441568

Article PDF–1.3M

Select item 805725816.

RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis

Artem Kalinichenko, Giovanna Perinetti Casoni, Loïc Dupré, Luca Trotta, Jakob Huemer, Donatella Galgano, Yolla German, Ben Haladik, Julia Pazmandi, Marini Thian, Özlem Yüce Petronczki, Samuel C. Chiang, Mervi Taskinen, Anne Hekkala, Saila Kauppila, Outi Lindgren, Terhi Tapiainen, Michael J. Kraakman, Kim Vettenranta, Alexis J. Lomakin, Janna Saarela, Mikko R. J. Seppänen, Yenan T. Bryceson, Kaan Boztug

Blood. 2021 Apr 15; 137(15): 2033–2045. Prepublished online 2021 Jan 29. doi: 10.1182/blood.2020008738

PMCID:: PMC8057258

Article

Select item 367871917.

Exome and whole genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

Austin M. Dulak, Petar Stojanov, Shouyong Peng, Michael S. Lawrence, Cameron Fox, Chip Stewart, Santhoshi Bandla, Yu Imamura, Steven E. Schumacher, Erica Shefler, Aaron McKenna, Kristian Cibulskis, Andrey Sivachenko, Scott L. Carter, Gordon Saksena, Douglas Voet, Alex H. Ramos, Daniel Auclair, Kristin Thompson, Carrie Sougnez, Robert C. Onofrio, Candace Guiducci, Rameen Beroukhim, David Zhou, Lin Lin, Jules Lin, Rishindra Reddy, Andrew Chang, James D. Luketich, Arjun Pennathur, Shuji Ogino, Todd R. Golub, Stacey B. Gabriel, Eric S. Lander, David G. Beer, Tony E. Godfrey, Gad Getz, Adam J. Bass

Nat Genet. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Nat Genet. 2013 May; 45(5): 478–486. Published online 2013 Mar 24. doi: 10.1038/ng.2591

PMCID:: PMC3678719

Article PDF–1.3M

Select item 295683818.

Upregulation of fibronectin expression by COX-2 is mediated by interaction with ELMO1

Chen Yang, Andrey Sorokin

Cell Signal. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Cell Signal. 2011 Jan; 23(1): 99–104. Published online 2010 Aug 21. doi: 10.1016/j.cellsig.2010.08.008

PMCID:: PMC2956838

Article PDF–364K

Select item 257515019.

An α-Helical Extension of the ELMO1 Pleckstrin Homology Domain Mediates Direct Interaction to DOCK180 and Is Critical in Rac Signaling

David Komander, Manishha Patel, Mélanie Laurin, Nadine Fradet, Ariane Pelletier, David Barford, Jean-François Côté

Mol Biol Cell. 2008 Nov; 19(11): 4837–4851. doi: 10.1091/mbc.E08-04-0345

PMCID:: PMC2575150

Article PDF–2.4M

Select item 412706620.

Essential role of Elmo1 in Dock2-dependent lymphocyte migration

Catherine Stevenson, Gonzalo de la Rosa, Christopher S. Anderson, Patrick S. Murphy, Tara Capece, Minsoo Kim and Michael R. Elliott

J Immunol. Author manuscript; available in PMC 2015 Jun 15.

Published in final edited form as: J Immunol. 2014 Jun 15; 192(12): 6062–6070. Published online 2014 May 12. doi: 10.4049/jimmunol.1303348

PMCID:: PMC4127066

Article PDF–1.5M

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