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Select item 47133641.

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

J D Mosley, C M Shaffer, S L Van Driest, P E Weeke, Q S Wells, J H Karnes, D R Velez Edwards, W-Q Wei, P L Teixeira, L Bastarache, D C Crawford, R Li, T A Manolio, E P Bottinger, C A McCarty, J G Linneman, M H Brilliant, J A Pacheco, W Thompson, R L Chisholm, G P Jarvik, D R Crosslin, D S Carrell, E Baldwin, J Ralston, E B Larson, J Grafton, A Scrol, H Jouni, I J Kullo, G Tromp, K M Borthwick, H Kuivaniemi, D J Carey, M D Ritchie, Y Bradford, S S Verma, C G Chute, A Veluchamy, M K Siddiqui, C N A Palmer, A Doney, S H MahmoudPour, A H Maitland-van der Zee, A D Morris, J C Denny, D M Roden

Pharmacogenomics J. 2016 Jun; 16(3): 231–237. Published online 2015 Jul 14. doi: 10.1038/tpj.2015.51

PMCID:: PMC4713364

Article PDF–420K

Select item 31055412.

RNA polymerase III drives alternative splicing of the potassium channel–interacting protein contributing to brain complexity and neurodegeneration

Sara Massone, Irene Vassallo, Manuele Castelnuovo, Gloria Fiorino, Elena Gatta, Mauro Robello, Roberta Borghi, Massimo Tabaton, Claudio Russo, Giorgio Dieci, Ranieri Cancedda, Aldo Pagano

J Cell Biol. 2011 May 30; 193(5): 851–866. doi: 10.1083/jcb.201011053

PMCID:: PMC3105541

Article PDF–3.3M

Select item 36634983.

Auxiliary KChIP4a Suppresses A-type K⁺ Current through Endoplasmic Reticulum (ER) Retention and Promoting Closed-state Inactivation of Kv4 Channels

Yi-Quan Tang, Ping Liang, Jingheng Zhou, Yanxin Lu, Lei Lei, Xiling Bian, KeWei Wang

J Biol Chem. 2013 May 24; 288(21): 14727–14741. Published online 2013 Apr 10. doi: 10.1074/jbc.M113.466052

PMCID:: PMC3663498

Article PDF–4.6M

Select item 35729534.

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

Blanca E. Himes, Keith Sheppard, Annerose Berndt, Adriana S. Leme, Rachel A. Myers, Christopher R. Gignoux, Albert M. Levin, W. James Gauderman, James J. Yang, Rasika A. Mathias, Isabelle Romieu, Dara G. Torgerson, Lindsey A. Roth, Scott Huntsman, Celeste Eng, Barbara Klanderman, John Ziniti, Jody Senter-Sylvia, Stanley J. Szefler, Robert F. Lemanske, Jr, Robert S. Zeiger, Robert C. Strunk, Fernando D. Martinez, Homer Boushey, Vernon M. Chinchilli, Elliot Israel, David Mauger, Gerard H. Koppelman, Dirkje S. Postma, Maartje A. E. Nieuwenhuis, Judith M. Vonk, John J. Lima, Charles G. Irvin, Stephen P. Peters, Michiaki Kubo, Mayumi Tamari, Yusuke Nakamura, Augusto A. Litonjua, Kelan G. Tantisira, Benjamin A. Raby, Eugene R. Bleecker, Deborah A. Meyers, Stephanie J. London, Kathleen C. Barnes, Frank D. Gilliland, L. Keoki Williams, Esteban G. Burchard, Dan L. Nicolae, Carole Ober, Dawn L. DeMeo, Edwin K. Silverman, Beverly Paigen, Gary Churchill, Steve D. Shapiro, Scott T. Weiss

PLoS One. 2013; 8(2): e56179. Published online 2013 Feb 14. doi: 10.1371/journal.pone.0056179

PMCID:: PMC3572953

Article PDF–783K

Select item 40671955.

The Stoichiometry and Biophysical Properties of the Kv4 Potassium Channel Complex with K⁺ Channel-interacting Protein (KChIP) Subunits Are Variable, Depending on the Relative Expression Level

Masahiro Kitazawa, Yoshihiro Kubo, Koichi Nakajo

J Biol Chem. 2014 Jun 20; 289(25): 17597–17609. Published online 2014 May 8. doi: 10.1074/jbc.M114.563452

PMCID:: PMC4067195

Article PDF–3.2M

Select item 32479856.

Structural Requirements for Interaction of Peroxisomal Targeting Signal 2 and Its Receptor PEX7

Markus Kunze, Georg Neuberger, Sebastian Maurer-Stroh, Jianmin Ma, Thomas Eck, Nancy Braverman, Johannes A. Schmid, Frank Eisenhaber, Johannes Berger

J Biol Chem. 2011 Dec 30; 286(52): 45048–45062. Published online 2011 Nov 5. doi: 10.1074/jbc.M111.301853

PMCID:: PMC3247985

Article PDF–4.4M

Select item 26029207.

Multiple Kv Channel-interacting Proteins Contain an N-terminal Transmembrane Domain That Regulates Kv4 Channel Trafficking and Gating

Henry H. Jerng, Paul J. Pfaffinger

J Biol Chem. 2008 Dec 19; 283(51): 36046–36059. doi: 10.1074/jbc.M806852200

PMCID:: PMC2602920

Article PDF–2.0M

Select item 24745598.

Specific effects of KChIP3/calsenilin/DREAM, but not KChIPs 1, 2 and 4, on calcium signalling and regulated secretion in PC12 cells

Neil Venn, Lee P. Haynes, Robert D. Burgoyne

Biochem J. 2008 Jul 1; 413(Pt 1): 71–80. Prepublished online 2008 Apr 7. Published online 2008 Jun 12. doi: 10.1042/BJ20080441

PMCID:: PMC2474559

Article PDF–1.1M

Select item 30150949.

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

Leonid Padyukov, Mark Seielstad, Rick T H Ong, Bo Ding, Johan Rönnelid, Maria Seddighzadeh, Lars Alfredsson, Lars Klareskog, the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) Study Group

Ann Rheum Dis. 2011 Feb; 70(2): 259–265. Published online 2010 Dec 14. doi: 10.1136/ard.2009.126821

PMCID:: PMC3015094

Article PDF–466K

Select item 282381010.

KChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation

Lin Lin, Wei Sun, Andrew M. Wikenheiser, Faith Kung, Dax A. Hoffman

Mol Cell Neurosci. Author manuscript; available in PMC 2011 Mar 1.

Published in final edited form as: Mol Cell Neurosci. 2010 Mar; 43(3): 315–325. Published online 2010 Jan 4. doi: 10.1016/j.mcn.2009.12.005

PMCID:: PMC2823810

Article PDF–1.8M

Select item 11779911.

Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain

Mats H. Holmqvist, Jie Cao, Ricardo Hernandez-Pineda, Michael D. Jacobson, Karen I. Carroll, M. Amy Sung, Maria Betty, Pei Ge, Kevin J. Gilbride, Melissa E. Brown, Mark E. Jurman, Deborah Lawson, Inmaculada Silos-Santiago, Yu Xie, Manuel Covarrubias, Kenneth J. Rhodes, Peter S. Distefano, W. Frank An

Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2): 1035–1040. doi: 10.1073/pnas.022509299

PMCID:: PMC117799

Article PDF–442K

Select item 243059612.

Molecular Genetics of Successful Smoking Cessation: Convergent Genome-Wide Association Study Results

George R. Uhl, Qing-Rong Liu, Tomas Drgon, Catherine Johnson, Donna Walther, Jed E. Rose, Sean P. David, Ray Niaura, Caryn Lerman

Arch Gen Psychiatry. Author manuscript; available in PMC 2008 Jun 17.

Published in final edited form as: Arch Gen Psychiatry. 2008 Jun; 65(6): 683–693. doi: 10.1001/archpsyc.65.6.683

PMCID:: PMC2430596

Article PDF–1.0M

Select item 356108413.

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan

PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225

PMCID:: PMC3561084

Article PDF–1.0M

Select item 488219014.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Article PDF–1.9M

Select item 352258715.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Article PDF–130K

Select item 184794816.

Large-scale mapping of human protein–protein interactions by mass spectrometry

Rob M Ewing, Peter Chu, Fred Elisma, Hongyan Li, Paul Taylor, Shane Climie, Linda McBroom-Cerajewski, Mark D Robinson, Liam O'Connor, Michael Li, Rod Taylor, Moyez Dharsee, Yuen Ho, Adrian Heilbut, Lynda Moore, Shudong Zhang, Olga Ornatsky, Yury V Bukhman, Martin Ethier, Yinglun Sheng, Julian Vasilescu, Mohamed Abu-Farha, Jean-Philippe Lambert, Henry S Duewel, Ian I Stewart, Bonnie Kuehl, Kelly Hogue, Karen Colwill, Katharine Gladwish, Brenda Muskat, Robert Kinach, Sally-Lin Adams, Michael F Moran, Gregg B Morin, Thodoros Topaloglou, Daniel Figeys

Mol Syst Biol. 2007; 3: 89. Published online 2007 Mar 13. doi: 10.1038/msb4100134

PMCID:: PMC1847948

Article PDF–440K

Select item 319082617.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Article PDF–5.7M

Select item 289646418.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Article PDF–2.4M

Select item 461721119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Article PDF–2.2M

Select item 716998320.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Article PDF–5.4M

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