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Select item 108975211.

UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas

Shiqin Liu, Timothy Chai, Fernando Garcia-Marques, Qingqing Yin, En-Chi Hsu, Michelle Shen, Angus Martin Shaw Toland, Abel Bermudez, Alifiani B. Hartono, Christopher F. Massey, Chung S. Lee, Liwei Zheng, Maya Baron, Caden J. Denning, Merve Aslan, Holly M. Nguyen, Rosalie Nolley, Amina Zoubeidi, Millie Das, Christian A. Kunder, Brooke E. Howitt, H. Tom Soh, Irving L. Weissman, Michael A. Liss, Arnold I. Chin, James D. Brooks, Eva Corey, Sharon J. Pitteri, Jiaoti Huang, Tanya Stoyanova

Cell Rep Med. 2024 Feb 20; 5(2): 101381. Published online 2024 Jan 19. doi: 10.1016/j.xcrm.2023.101381

PMCID:: PMC10897521

Abstract Article PDF–7.7M

Select item 103825052.

UCHL1 facilitates protein aggregates clearance to enhance neural stem cell activation in spinal cord injury

Lu Ding, Weiwei Chu, Yu Xia, Ming Shi, Tian Li, Feng-Quan Zhou, David Y. B. Deng

Cell Death Dis. 2023 Jul; 14(7): 479. Published online 2023 Jul 28. doi: 10.1038/s41419-023-06003-8

PMCID:: PMC10382505

Abstract Article PDF–18M

Select item 99535233.

Pivotal Role of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) in Uterine Leiomyoma

Tomoo Suzuki, Yidan Dai, Masanori Ono, Junya Kojima, Toru Sasaki, Hiroshi Fujiwara, Naoaki Kuji, Hirotaka Nishi

Biomolecules. 2023 Feb; 13(2): 193. Published online 2023 Jan 18. doi: 10.3390/biom13020193

PMCID:: PMC9953523

Abstract Article PDF–2.1M

Select item 92938984.

Ubiquitin carboxyl-terminal esterase L1 is not elevated in the serum of concussed rugby players: an observational cross-sectional study

Jazmin O. Harrell, Jessica E. Morgan, Steven D. Beck, Iustin C. Scobercea, Julien S. Baker, Allan Knox, Jorge M. Serrador, Matthew J. Rogatzki

Sci Rep. 2022; 12: 12230. Published online 2022 Jul 18. doi: 10.1038/s41598-022-16447-1

PMCID:: PMC9293898

Abstract Article PDF–964K

Select item 90926735.

UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

Jianbo Yao, Abdusemer Reyimu, Ao Sun, Zaxi Duoji, Wubi Zhou, Song Liang, Suxia Hu, Xiang Wang, Jingjing Dai, Xiaoguang Xu

World J Surg Oncol. 2022; 20: 153. Published online 2022 May 11. doi: 10.1186/s12957-022-02620-3

PMCID:: PMC9092673

Abstract Article PDF–1.4M

Select item 90063806.

Ubiquitin C-terminal hydrolase L1 promotes lymph node metastasis in small cell neuroendocrine carcinomas of the cervix

Yunqiang Zhang, Jingxin Ding, Xuyin Zhang, Keqin Hua

J Int Med Res. 2022 Apr; 50(4): 03000605221087620. Published online 2022 Apr 11. doi: 10.1177/03000605221087620

PMCID:: PMC9006380

Abstract Article PDF–1.1M

Select item 82622417.

Targeting UCHL1 Induces Cell Cycle Arrest in High-Risk Multiple Myeloma with t(4;14)

Parin Kamseng, Teerapong Siriboonpiputtana, Teeraya Puavilai, Suporn Chuncharunee, Karan Paisooksantivatana, Takol Chareonsirisuthigul, Mutita Junking, Wannasiri Chiraphapphaiboon, Pa-thai Yenchitsomanus, Budsaba Rerkamnuaychoke

Pathol Oncol Res. 2021; 27: 606567. Published online 2021 Mar 31. doi: 10.3389/pore.2021.606567

PMCID:: PMC8262241

Abstract Article PDF–2.9M

Select item 72550028.

The deubiquitinating enzyme UCHL1 promotes resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase

Xinyuan Ding, Yuting Gu, Min Jin, Xin Guo, Sudong Xue, Caihong Tan, Jiefang Huang, Wanlin Yang, Mingxing Xue, Qianjun Zhou, Wenjuan Wang, Yanyun Zhang

Theranostics. 2020; 10(13): 6048–6060. Published online 2020 May 15. doi: 10.7150/thno.42096

PMCID:: PMC7255002

Abstract Article PDF–3.3M

Select item 70045279.

Ubiquitin C‐terminal hydrolase‐L1 has prognostic relevance and is a therapeutic target for high‐grade neuroendocrine lung cancers

Yoshihisa Shimada, Yujin Kudo, Sachio Maehara, Jun Matsubayashi, Yoichi Otaki, Naohiro Kajiwara, Tatsuo Ohira, John D. Minna, Norihiko Ikeda

Cancer Sci. 2020 Feb; 111(2): 610–620. Published online 2020 Jan 19. doi: 10.1111/cas.14284

PMCID:: PMC7004527

Abstract Article PDF–1.3M

Select item 675711710.

Serum ubiquitin C‐terminal hydrolase L1 predicts cognitive impairment in patients with acute organophosphorus pesticide poisoning

Li Pang, Junlan Liu, Wei Li, Yan Xia, Jihong Xing

J Clin Lab Anal. 2019 Sep; 33(7): e22947. Published online 2019 Jun 14. doi: 10.1002/jcla.22947

PMCID:: PMC6757117

Abstract Article PDF–523K

Select item 620319211.

The deubiquitinating enzyme UCHL1 is a favorable prognostic marker in neuroblastoma as it promotes neuronal differentiation

Yuting Gu, Fan Lv, Mingxing Xue, Kai Chen, Cheng Cheng, Xinyuan Ding, Min Jin, Guofeng Xu, Yanyun Zhang, Zhixiang Wu, Leizhen Zheng, Yeming Wu

J Exp Clin Cancer Res. 2018; 37: 258. Published online 2018 Oct 25. doi: 10.1186/s13046-018-0931-z

PMCID:: PMC6203192

Abstract Article PDF–5.7M

Select item 608348612.

UCHL1/PGP 9.5 Dynamic in Neuro-Immune-Cutaneous Milieu: Focusing on Axonal Nerve Terminals and Epidermal Keratinocytes in Psoriatic Itch

Piotr Kupczyk, Adam Reich, Mariusz Gajda, Marcin Hołysz, Edyta Wysokińska, Maria Paprocka, Dmitry Nevozhay, Grzegorz Chodaczek, Paweł P. Jagodziński, Piotr Ziółkowski, Jacek C. Szepietowski

Biomed Res Int. 2018; 2018: 7489316. Published online 2018 Jul 25. doi: 10.1155/2018/7489316

PMCID:: PMC6083486

Abstract Article PDF–4.9M

Select item 595401813.

Long non-coding RNA expression patterns in lung tissues of chronic cigarette smoke induced COPD mouse model

Haiyun Zhang, Dejun Sun, Defu Li, Zeguang Zheng, Jingyi Xu, Xue Liang, Chenting Zhang, Sheng Wang, Jian Wang, Wenju Lu

Sci Rep. 2018; 8: 7609. Published online 2018 May 15. doi: 10.1038/s41598-018-25702-3

Correction in:: Sci Rep. 2019; 9: 7398.

PMCID:: PMC5954018

Abstract Article PDF–2.2M

Select item 590941814.

Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma

Guangshan Yang, Gaofei Fan, Tengyue Zhang, Kelong Ma, Jin Huang, Miao Liu, Xiaolu Teng, Kun Xu, Pingsheng Fan, Dongmiao Cheng

Med Sci Monit. 2018; 24: 2072–2082. Published online 2018 Apr 8. doi: 10.12659/MSM.908925

PMCID:: PMC5909418

Abstract Article PDF–1.5M

Select item 579875715.

Overexpression of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in boys with cryptorchidism

Dorota Toliczenko-Bernatowicz, Ewa Matuszczak, Marzena Tylicka, Beata Szymańska, Marta Komarowska, Ewa Gorodkiewicz, Wojciech Debek, Adam Hermanowicz

PLoS One. 2018; 13(2): e0191806. Published online 2018 Feb 5. doi: 10.1371/journal.pone.0191806

PMCID:: PMC5798757

Abstract Article PDF–799K

Select item 549367916.

Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes

Ju-Chien Cheng, Ching-Ping Tseng, Mei-Huei Liao, Cheng-Yuan Peng, Jau-Song Yu, Po-Heng Chuang, Jing-Tang Huang, Jeremy J. W. Chen

Sci Rep. 2017; 7: 4448. Published online 2017 Jun 30. doi: 10.1038/s41598-017-04259-7

PMCID:: PMC5493679

Abstract Article PDF–1.7M

Select item 541760117.

Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma

Patricia C. Sanchez-Diaz, Judy C. Chang, Emily S. Moses, Tu Dao, Yidong Chen, Jaclyn Y. Hung

PLoS One. 2017; 12(5): e0176879. Published online 2017 May 4. doi: 10.1371/journal.pone.0176879

PMCID:: PMC5417601

Abstract Article PDF–1.8M

Select item 519247618.

Characterization of the Folding of a 5₂-Knotted Protein Using Engineered Single-Tryptophan Variants

Hongyu Zhang, Sophie E. Jackson

Biophys J. 2016 Dec 20; 111(12): 2587–2599. Published online 2016 Dec 20. doi: 10.1016/j.bpj.2016.10.029

PMCID:: PMC5192476

Abstract Article PDF–1.3M

Select item 487800419.

Automated PGP9.5 immunofluorescence staining: a valuable tool in the assessment of small fiber neuropathy?

Nathalie Van Acker, Michael Ragé, Ellen Sluydts, Michiel W. M. Knaapen, Martine De Bie, Maarten Timmers, Erik Fransen, Carla Duymelinck, Stefanie De Schepper, Praveen Anand, Theo Meert, Léon Plaghki, Patrick Cras

BMC Res Notes. 2016; 9: 280. Published online 2016 May 23. doi: 10.1186/s13104-016-2085-4

PMCID:: PMC4878004

Abstract Article PDF–1.1M

Select item 486644220.

Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease

Caroline L. Wilson, Lindsay B. Murphy, Jack Leslie, Stuart Kendrick, Jeremy French, Christopher R. Fox, Neil S. Sheerin, Andrew Fisher, John H. Robinson, Dina G. Tiniakos, Douglas A. Gray, Fiona Oakley, Derek A. Mann

J Hepatol. Author manuscript; available in PMC 2016 May 13.

Published in final edited form as: J Hepatol. 2015 Dec; 63(6): 1421–1428. Published online 2015 Aug 8. doi: 10.1016/j.jhep.2015.07.034

PMCID:: PMC4866442

Abstract Article PDF–2.0M

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