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Select item 90445871.

Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway

Jie Zhang, Zhangchao Guo, Qiangli Xie, Chuanhong Zhong, Xiangyu Gao, Qiumei Yang

BMC Cancer. 2022; 22: 457. Published online 2022 Apr 26. doi: 10.1186/s12885-022-09569-2

PMCID:: PMC9044587

Article PDF–4.4M

Select item 86851722.

Association between Smoking Habits and Tryptophan Hydroxylase Gene C218A Polymorphism among the Japanese Population

Shoichi Mizuno, Hidemi Ito, Nobuyuki Hamajima, Akiko Tamakoshi, Kaoru Hirose, Kazuo Tajima

J Epidemiol. 2004; 14(3): 94–99. Published online 2005 Mar 18. doi: 10.2188/jea.14.94

PMCID:: PMC8685172

Article PDF–38K

Select item 85887063.

TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan hydroxylase 1 concentrations in acute pancreatitis patients

Jadwiga Snarska, Ewa Fiedorowicz, Dominika Rozmus, Konrad Wroński, Maria Latacz, Natalia Kordulewska, Janusz Płomiński, Roman Grzybowski, Huub F.J. Savelkoul, Elżbieta Kostyra, Anna Cieślińska

BMC Gastroenterol. 2021; 21: 426. Published online 2021 Nov 12. doi: 10.1186/s12876-021-02012-z

PMCID:: PMC8588706

Article PDF–1.6M

Select item 78379094.

Association study of single nucleotide polymorphism in tryptophan hydroxylase 1 gene with adolescent idiopathic scoliosis: A meta-analysis

Junyu Li, Zexi Yang, Miao Yu

Medicine (Baltimore) 2021 Jan 22; 100(3): e23733. Published online 2021 Jan 22. doi: 10.1097/MD.0000000000023733

PMCID:: PMC7837909

Article PDF–1.0M

Select item 69286145.

An Ancient Mutation in the TPH1 Gene is Consistent with the Changes in Mammalian Reproductive Rhythm

Chenhui Liu, Xunping Jiang, Guiqiong Liu, Teketay Wassie, Shishay Girmay

Int J Mol Sci. 2019 Dec; 20(23): 6065. Published online 2019 Dec 2. doi: 10.3390/ijms20236065

PMCID:: PMC6928614

Article PDF–1.4M

Select item 50852236.

Androgen suppresses testicular cancer cell growth in vitro and in vivo

Hideo Nakagawa, Takashi Ueda, Saya Ito, Takumi Shiraishi, Hidefumi Taniguchi, Naruhiro Kayukawa, Hiroyuki Nakanishi, So Ushijima, Motohiro Kanazawa, Terukazu Nakamura, Yoshio Naya, Fumiya Hongo, Kazumi Kamoi, Koji Okihara, Osamu Ukimura

Oncotarget. 2016 Jun 7; 7(23): 35224–35232. Published online 2016 Apr 29. doi: 10.18632/oncotarget.9109

PMCID:: PMC5085223

Article PDF–2.8M

Select item 49355737.

The Regulatory Domain of Human Tryptophan Hydroxylase 1 Forms a Stable Dimer

Shengnan Zhang, Cynthia S. Hinck, Paul F. Fitzpatrick

Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Aug 5.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Aug 5; 476(4): 457–461. Published online 2016 May 30. doi: 10.1016/j.bbrc.2016.05.144

PMCID:: PMC4935573

Article PDF–1.5M

Select item 44405508.

Increased risk of suicide attempt in mood disorders and TPH1 genotype

Hanga Galfalvy, Yung-yu Huang, Maria A. Oquendo, Dianne Currier, J. John Mann

J Affect Disord. Author manuscript; available in PMC 2015 May 21.

Published in final edited form as: J Affect Disord. 2009 Jun; 115(3): 331–338. Published online 2008 Oct 31. doi: 10.1016/j.jad.2008.09.019

PMCID:: PMC4440550

Article PDF–304K

Select item 40676979.

Identification of a Functional TPH1 Polymorphism Associated with Irritable Bowel Syndrome Bowel Habit Subtypes

Helmut Grasberger, Lin Chang, Wendy Shih, Angela P. Presson, Gregory S. Sayuk, Rodney D. Newberry, Iordanis Karagiannides, Charalabos Pothoulakis, Emeran Mayer, Juanita L. Merchant

Am J Gastroenterol. Author manuscript; available in PMC 2014 Jun 24.

Published in final edited form as: Am J Gastroenterol. 2013 Nov; 108(11): 1766–1774. Published online 2013 Sep 24. doi: 10.1038/ajg.2013.304

PMCID:: PMC4067697

Article PDF–793K

Select item 376640510.

TPH Gene Polymorphisms Are Associated With Disease Perception and Quality of Life in Women With Irritable Bowel Syndrome

Sang-Eun Jun, Ruth Kohen, Kevin C. Cain, Monica E. Jarrett, Margaret M. Heitkemper

Biol Res Nurs. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Biol Res Nurs. 2014 Jan; 16(1): 10.1177/1099800412466694. Published online 2012 Nov 20. doi: 10.1177/1099800412466694

PMCID:: PMC3766405

Article PDF–108K

Select item 370428411.

TPH1 A218C polymorphism and temperament in major depression

Kadri Andre, Olli Kampman, Merja Viikki, Ari Illi, Eija Setälä-Soikkeli, Outi Poutanen, Nina Mononen, Esa Leinonen, Terho Lehtimäki

BMC Psychiatry. 2013; 13: 118. Published online 2013 Apr 18. doi: 10.1186/1471-244X-13-118

PMCID:: PMC3704284

Article PDF–235K

Select item 324189612.

Interaction between Tryptophan Hydroxylase I (TPH1) Polymorphisms and Childhood Abuse is Associated with Increased Risk for Borderline Personality Disorder in Adulthood

Scott T. Wilson, Barbara Stanley, David A. Brent, Maria A. Oquendo, Yung-yu Huang, Fatemeh Haghighi, Colin A. Hodgkinson, J. John Mann

Psychiatr Genet. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Psychiatr Genet. 2012 Feb; 22(1): 15–24. doi: 10.1097/YPG.0b013e32834c0c4c

PMCID:: PMC3241896

Article PDF–473K

Select item 279997413.

No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population

Youl-Ri Kim, Joo Young Lee, Sung Kil Min

Yonsei Med J. 2010 Jan 1; 51(1): 27–32. Published online 2009 Dec 29. doi: 10.3349/ymj.2010.51.1.27

PMCID:: PMC2799974

Article PDF–137K

Select item 279603614.

An Association Study of the A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene with Eating Disorders in a Korean Population: A Pilot Study

Youl-Ri Kim, Jong-Min Woo, Si Young Heo, Jeong Hyun Kim, Soo-Jin Lim, Bum-Hee Yu

Psychiatry Investig. 2009 Mar; 6(1): 44–49. Published online 2009 Mar 31. doi: 10.4306/pi.2009.6.1.44

PMCID:: PMC2796036

Article PDF–420K

Select item 267401815.

The Tryptophan Hydroxylase-1 A218C polymorphism is associated with diagnosis, but not suicidal behavior, in borderline personality disorder

Scott T. Wilson, Barbara Stanley, David A. Brent, Maria A. Oquendo, Yung-yu Huang, J. John Mann

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Mar 5.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5; 150B(2): 202–208. doi: 10.1002/ajmg.b.30788

PMCID:: PMC2674018

Article PDF–89K

Select item 256464416.

Association of TPH1 with suicidal behaviour and psychiatric disorders in the Chinese population

X Liu, H Li, W Qin, G He, D Li, Y Shen, J Shen, N Gu, G Feng, L He

J Med Genet. 2006 Feb; 43(2): e4. doi: 10.1136/jmg.2004.029397

PMCID:: PMC2564644

Article PDF–242K

Select item 168289917.

Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism.

D A Nielsen, M Dean, D Goldman

Am J Hum Genet. 1992 Dec; 51(6): 1366–1371.

PMCID:: PMC1682899

Summary Page Browse PDF–1.0M

Select item 33119818.

Complete coding sequence of human tryptophan hydroxylase.

S Boularand, M C Darmon, Y Ganem, J M Launay, J Mallet

Nucleic Acids Res. 1990 Jul 25; 18(14): 4257. doi: 10.1093/nar/18.14.4257

PMCID:: PMC331198

Summary Page Browse PDF–211K

Select item 1095461119.

A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis

Teresa Zelante, Giuseppe Paolicelli, Francesca Fallarino, Marco Gargaro, Gianluca Vascelli, Marco De Zuani, Jan Fric, Petra Laznickova, Marcela Hortova Kohoutkova, Antonio Macchiarulo, Daniela Dolciami, Giuseppe Pieraccini, Lorenzo Gaetani, Giulia Scalisi, Caterina Trevisan, Barbara Frossi, Carlo Pucillo, Antonella De Luca, Emilia Nunzi, Roberta Spaccapelo, Marilena Pariano, Monica Borghi, Francesca Boscaro, Riccardo Romoli, Andrea Mancini, Lucia Gentili, Giorgia Renga, Claudio Costantini, Matteo Puccetti, Stefano Giovagnoli, Maurizio Ricci, Martina Antonini, Paolo Calabresi, Paolo Puccetti, Massimiliano Di Filippo, Luigina Romani

Sci Rep. 2024; 14: 6651. Published online 2024 Mar 20. doi: 10.1038/s41598-024-57400-8

PMCID:: PMC10954611

Article PDF–2.1M

Select item 644378020.

Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

Dan-Qian Chen, Gang Cao, Hua Chen, Christos P. Argyopoulos, Hui Yu, Wei Su, Lin Chen, David C. Samuels, Shougang Zhuang, George P. Bayliss, Shilin Zhao, Xiao-Yong Yu, Nosratola D. Vaziri, Ming Wang, Dan Liu, Jia-Rong Mao, Shi-Xing Ma, Jin Zhao, Yuan Zhang, You-Quan Shang, Huining Kang, Fei Ye, Xiao-Hong Cheng, Xiang-Ri Li, Li Zhang, Mei-Xia Meng, Yan Guo, Ying-Yong Zhao

Nat Commun. 2019; 10: 1476. Published online 2019 Apr 1. doi: 10.1038/s41467-019-09329-0

PMCID:: PMC6443780

Article PDF–4.6M

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