PMC Links for Gene (Select 6566) - PMC

Magdalena Dzitkowska-Zabielska, Aleksandra Bojarczuk, Małgorzata Borczyk, Marcin Piechota, Michał Korostyński, Jakub Grzegorz Adamczyk, Grzegorz Trybek, Myosotis Massidda, Paweł Cięszczyk

Genes (Basel) 2022 May; 13(5): 870. Published online 2022 May 12. doi: 10.3390/genes13050870

PMCID:: PMC9142056

Abstract Article PDF–282K

Select item 88671954.

A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes‐Associated Breast Cancer

Qiongyu Hao, Zhimin Huang, Qun Li, Dingxie Liu, Piwen Wang, Kun Wang, Jieqing Li, Wei Cao, Wenhong Deng, Ke Wu, Rui Su, Zhongmin Liu, Jay Vadgama, Yong Wu

Adv Sci (Weinh) 2022 Feb; 9(6): 2102303. Published online 2022 Jan 12. doi: 10.1002/advs.202102303

PMCID:: PMC8867195

Abstract Article PDF–2.0M

Select item 79707075.

Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition

Aaminah Khan, Emanuele Valli, Hayley Lam, David A. Scott, Jayne Murray, Georgina Eden, Laura D. Gamble, Rupinder Pandher, Claudia L. Flemming, Sophie Allan, Andrei L. Osterman, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Denise M.T. Yu

Oncogene. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Oncogene. 2020 Apr; 39(17): 3555–3570. Published online 2020 Mar 2. doi: 10.1038/s41388-020-1235-2

PMCID:: PMC7970707

Abstract Article PDF–1.7M

Select item 79073486.

Monocarboxylate transporter-1 (MCT1) protein expression in head and neck cancer affects clinical outcome

Martin Leu, J. Kitz, Y. Pilavakis, S. Hakroush, H. A. Wolff, M. Canis, S. Rieken, M. A. Schirmer

Sci Rep. 2021; 11: 4578. Published online 2021 Feb 25. doi: 10.1038/s41598-021-84019-w

PMCID:: PMC7907348

Abstract Article PDF–899K

Select item 74867677.

Hyperpolarized [1-¹³C]pyruvate-to-[1-¹³C]lactate conversion is rate-limited by monocarboxylate transporter-1 in the plasma membrane

Yi Rao, Seth Gammon, Niki M. Zacharias, Tracy Liu, Travis Salzillo, Yuanxin Xi, Jing Wang, Pratip Bhattacharya, David Piwnica-Worms

Proc Natl Acad Sci U S A. 2020 Sep 8; 117(36): 22378–22389. Published online 2020 Aug 24. doi: 10.1073/pnas.2003537117

PMCID:: PMC7486767

Abstract Article PDF–1.6M

Select item 73463108.

Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene

Marianna Avitabile, Mariangela Succoio, Alessandro Testori, Antonella Cardinale, Zalman Vaksman, Vito Alessandro Lasorsa, Sueva Cantalupo, Matteo Esposito, Flora Cimmino, Annalaura Montella, Daniela Formicola, Jan Koster, Virginia Andreotti, Paola Ghiorzo, Maria Fiammetta Romano, Stefania Staibano, Massimiliano Scalvenzi, Fabrizio Ayala, Hakon Hakonarson, Maria Valeria Corrias, Marcella Devoto, Matthew H Law, Mark M Iles, Kevin Brown, Sharon Diskin, Nicola Zambrano, Achille Iolascon, Mario Capasso

Carcinogenesis. 2020 May; 41(3): 284–295. Published online 2019 Sep 7. doi: 10.1093/carcin/bgz153

PMCID:: PMC7346310

Abstract Article PDF–8.9M

Select item 70844259.

Monocarboxylate Transporter 1 (MCT1) in Liver Pathology

Marek Droździk, Sylwia Szeląg-Pieniek, Justyna Grzegółkowska, Joanna Łapczuk-Romańska, Mariola Post, Pawel Domagała, Janusz Miętkiewski, Stefan Oswald, Mateusz Kurzawski

Int J Mol Sci. 2020 Mar; 21(5): 1606. Published online 2020 Feb 26. doi: 10.3390/ijms21051606

PMCID:: PMC7084425

Abstract Article PDF–3.3M

Select item 694938210.

Hyperpolarized MRI of human prostate cancer reveals increased lactate with tumor grade driven by monocarboxylate transporter 1

Kristin L. Granlund, Sui-Seng Tee, Hebert A. Vargas, Serge K. Lyashchenko, Ed Reznik, Samson Fine, Vincent Laudone, James A. Eastham, Karim A. Touijer, Victor E. Reuter, Mithat Gonen, Ramon E. Sosa, Duane Nicholson, YanWei W. Guo, Albert P. Chen, James Tropp, Fraser Robb, Hedvig Hricak, Kayvan R. Keshari

Cell Metab. Author manuscript; available in PMC 2021 Jan 7.

Published in final edited form as: Cell Metab. 2020 Jan 7; 31(1): 105–114.e3. Published online 2019 Sep 26. doi: 10.1016/j.cmet.2019.08.024

PMCID:: PMC6949382

Abstract Article PDF–1.3M

Select item 635396811.

HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma

Jason C. Fleming, Jeongmin Woo, Karwan Moutasim, Massimiliano Mellone, Steven J. Frampton, Abbie Mead, Waseem Ahmed, Oliver Wood, Hollie Robinson, Matthew Ward, Christopher H. Woelk, Christian H. Ottensmeier, Emma King, Dae Kim, Jeremy P. Blaydes, Gareth J. Thomas

Br J Cancer. 2019 Feb 5; 120(3): 356–367. Published online 2019 Jan 17. doi: 10.1038/s41416-018-0364-7

PMCID:: PMC6353968

Abstract Article PDF–1.6M

Select item 577560712.

Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells

Qing Fan, Liang Yang, Xiaodong Zhang, Yingbo Ma, Yan Li, Lei Dong, Zhihong Zong, Xiangdong Hua, Dongming Su, Hangyu Li, Jingang Liu

J Exp Clin Cancer Res. 2018; 37: 9. Published online 2018 Jan 19. doi: 10.1186/s13046-018-0673-y

PMCID:: PMC5775607

Abstract Article PDF–5.5M

Select item 570976813.

Branched‐chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype

Lidia Santos Silva, Gernot Poschet, Yannic Nonnenmacher, Holger M Becker, Sean Sapcariu, Ann‐Christin Gaupel, Magdalena Schlotter, Yonghe Wu, Niclas Kneisel, Martina Seiffert, Rüdiger Hell, Karsten Hiller, Peter Lichter, Bernhard Radlwimmer

EMBO Rep. 2017 Dec; 18(12): 2172–2185. Published online 2017 Oct 24. doi: 10.15252/embr.201744154

PMCID:: PMC5709768

Abstract Article PDF–1.5M

Select item 521680214.

Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas

Vera Miranda-Gonçalves, Sara Granja, Olga Martinho, Mrinalini Honavar, Marta Pojo, Bruno M. Costa, Manuel M. Pires, Célia Pinheiro, Michelle Cordeiro, Gil Bebiano, Paulo Costa, Rui M. Reis, Fátima Baltazar

Oncotarget. 2016 Jul 19; 7(29): 46335–46353. Published online 2016 Jun 16. doi: 10.18632/oncotarget.10114

PMCID:: PMC5216802

Abstract Article PDF–6.0M

Select item 507804415.

Monocarboxylate transporter 1 contributes to growth factor-induced tumor cell migration independent of transporter activity

Alana L. Gray, David T. Coleman, Runhua Shi, James A. Cardelli

Oncotarget. 2016 May 31; 7(22): 32695–32706. Published online 2016 Apr 26. doi: 10.18632/oncotarget.9016

PMCID:: PMC5078044

Abstract Article PDF–5.6M

Select item 505920316.

Heterozygous Monocarboxylate Transporter 1 (MCT1, SLC16A1) Deficiency as a Cause of Recurrent Ketoacidosis

Shanti Balasubramaniam, Barry Lewis, Lawrence Greed, David Meili, Annegret Flier, Raina Yamamoto, Karmen Bilić, Claudia Till, Jörn Oliver Sass

JIMD Rep. 2016; 29: 33–38. Published online 2015 Nov 26. doi: 10.1007/8904_2015_519

PMCID:: PMC5059203

Abstract Article PDF–187K

Select item 430368217.

Functional Characterization of 5-Oxoproline Transport via SLC16A1/MCT1

Shotaro Sasaki, Yuya Futagi, Masaki Kobayashi, Jiro Ogura, Ken Iseki

J Biol Chem. 2015 Jan 23; 290(4): 2303–2311. Published online 2014 Nov 4. doi: 10.1074/jbc.M114.581892

PMCID:: PMC4303682

Abstract Article PDF–1.8M

Select item 416559618.

Monocarboxylate Transporters 1–4 in NSCLC: MCT1 Is an Independent Prognostic Marker for Survival

Marte Eilertsen, Sigve Andersen, Samer Al-Saad, Yury Kiselev, Tom Donnem, Helge Stenvold, Ingvild Pettersen, Khalid Al-Shibli, Elin Richardsen, Lill-Tove Busund, Roy M. Bremnes

PLoS One. 2014; 9(9): e105038. Published online 2014 Sep 16. doi: 10.1371/journal.pone.0105038

PMCID:: PMC4165596

Abstract Article PDF–819K

Select item 416115219.

Synthesis and Structure–Activity Relationships of Pteridine Dione and Trione Monocarboxylate Transporter 1 Inhibitors

Hui Wang, Chunying Yang, Joanne R. Doherty, William R. Roush, John L. Cleveland, Thomas D. Bannister

J Med Chem. 2014 Sep 11; 57(17): 7317–7324. Published online 2014 Jul 28. doi: 10.1021/jm500640x

PMCID:: PMC4161152

Abstract Article PDF–775K

Select item 398262220.

S-Nitrosation of monocarboxylate transporter 1: Inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells

Anne R. Diers, Katarzyna A. Broniowska, Ching-Fang Chang, R. Blake Hill, Neil Hogg

Free Radic Biol Med. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Free Radic Biol Med. 2014 Apr; 69: 229–238. Published online 2014 Jan 30. doi: 10.1016/j.freeradbiomed.2014.01.031

PMCID:: PMC3982622

Abstract Article PDF–1.2M

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