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Select item 67869461.

Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness

Vijay S. Thakur, Brittany Aguila, Adina Brett-Morris, Chad J. Creighton, Scott M. Welford

Oncogene. Author manuscript; available in PMC 2020 Feb 9.

Published in final edited form as: Oncogene. 2019 Oct; 38(41): 6794–6800. Published online 2019 Aug 9. doi: 10.1038/s41388-019-0917-0

PMCID:: PMC6786946

Article PDF–2.4M

Select item 53520372.

Spermidine/spermine N¹-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells

Cong Wang, Ping Ruan, Ying Zhao, Xiaomin Li, Jun Wang, Xiaoxiao Wu, Tong Liu, Shasha Wang, Jiuzhou Hou, Wei Li, Qian Li, Jinghua Li, Fujun Dai, Dong Fang, Chaojie Wang, Songqiang Xie

Oncotarget. 2017 Jan 3; 8(1): 1092–1109. Published online 2016 Nov 25. doi: 10.18632/oncotarget.13582

PMCID:: PMC5352037

Article PDF–16M

Select item 48348743.

Isoform-level brain expression profiling of the spermidine/spermine N1-Acetyltransferase1 (SAT1) gene in major depression and suicide

Spiro P. Pantazatos, Stuart J. Andrews, Jane Dunning-Broadbent, Jiuhong Pang, Yung-yu Huang, Victoria Arango, Peter L. Nagy, J. John Mann

Neurobiol Dis. Author manuscript; available in PMC 2016 Apr 18.

Published in final edited form as: Neurobiol Dis. 2015 Jul; 79: 123–134. Published online 2015 May 8. doi: 10.1016/j.nbd.2015.04.014

PMCID:: PMC4834874

Article PDF–673K

Select item 45505554.

Depletion of the Polyamines Spermidine and Spermine by Overexpression of Spermidine/spermine N¹-Acetyltransferase1 (SAT1) Leads to Mitochondria-Mediated Apoptosis in Mammalian Cells

Swati Mandal, Ajeet Mandal, Myung Hee Park

Biochem J. Author manuscript; available in PMC 2015 Aug 26.

Published in final edited form as: Biochem J. 2015 Jun 15; 468(3): 435–447. Published online 2015 Apr 7. doi: 10.1042/BJ20150168

PMCID:: PMC4550555

Article PDF–1.0M

Select item 44754365.

Expression of Spermidine/Spermine N¹-Acetyl Transferase (SSAT) in Human Prostate Tissues is Related to Prostate Cancer Progression and Metastasis

Wei Huang, Jens C Eickhoff, Farideh Mehraein Ghomi, Dawn R. Church, George Wilding, Hirak S. Basu

Prostate. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: Prostate. 2015 Aug; 75(11): 1150–1159. Published online 2015 Apr 20. doi: 10.1002/pros.22996

PMCID:: PMC4475436

Article PDF–1.7M

Select item 44234046.

The polyamine catabolic enzymeSAT1 modulates tumorigenesis and radiation response in GBM

Adina Brett-Morris, Bradley M. Wright, Yuji Seo, Vinay Pasupuleti, Junran Zhang, Jun Lu, Raffaella Spina, Eli E. Bar, Maneesh Gujrati, Rebecca Schur, Zheng-Rong Lu, Scott M. Welford

Cancer Res. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Cancer Res. 2014 Dec 1; 74(23): 6925–6934. Published online 2014 Oct 2. doi: 10.1158/0008-5472.CAN-14-1249

PMCID:: PMC4423404

Article PDF–1.3M

Select item 38719777.

A Novel Assay Platform for the Detection of Translation Modulators of Spermidine/Spermine Acetyltransferase

Oscar Perez-Leal, Magid Abou-Gharbia, John Gordon, Wayne E. Childers, Salim Merali

Curr Pharm Des. Author manuscript; available in PMC 2014 Jan 23.

Published in final edited form as: Curr Pharm Des. 2014; 20(2): 245–252. doi: 10.2174/13816128113199990035

PMCID:: PMC3871977

Article PDF–955K

Select item 38526948.

Downregulation of the Polyamine Regulator Spermidine/Spermine N¹-Acetyltransferase by Epstein-Barr Virus in a Burkitt's Lymphoma Cell Line

Mingxia Shi, Yan-jun Gan, Timothy O. Davis, Rona S. Scott

Virus Res. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Virus Res. 2013 Oct; 177(1): 10.1016/j.virusres.2013.07.004. Published online 2013 Jul 25. doi: 10.1016/j.virusres.2013.07.004

PMCID:: PMC3852694

Article PDF–1.3M

Select item 35835199.

Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma

YE TIAN, SHIZHAO WANG, BIN WANG, JIANNING ZHANG, RONGCAI JIANG, WEI ZHANG

Oncol Rep. 2012 Apr; 27(4): 1227–1232. Published online 2011 Dec 14. doi: 10.3892/or.2011.1592

PMCID:: PMC3583519

Article PDF–415K

Select item 286532510.

Suppression of Exogenous Gene Expression by Spermidine/Spermine N¹-Acetyltransferase 1 (SSAT1) Cotransfection

Seung Bum Lee, Jong Hwan Park, Patrick M. Woster, Robert A. Casero, Jr., Myung Hee Park

J Biol Chem. 2010 May 14; 285(20): 15548–15556. Published online 2010 Mar 8. doi: 10.1074/jbc.M109.092007

PMCID:: PMC2865325

Article PDF–2.0M

Select item 251866611.

Mechanistic And Structural Analysis of Human Spermidine/spermine N¹-Acetyltransferase [hSSAT]

Subray S. Hegde, Jonathan Chandler, Matthew W. Vetting, Michael Yu, John S. Blanchard

Biochemistry. Author manuscript; available in PMC 2008 Aug 21.

Published in final edited form as: Biochemistry. 2007 Jun 19; 46(24): 7187–7195. Published online 2007 May 22. doi: 10.1021/bi700256z

PMCID:: PMC2518666

Article PDF–1.6M

Select item 138603012.

Induction of spermidine/spermine N¹-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells

Naveen Babbar, Eugene W. Gerner, Robert A. Casero, Jr

Biochem J. 2006 Feb 15; 394(Pt 1): 317–324. Prepublished online 2005 Nov 1. Published online 2006 Jan 27. doi: 10.1042/BJ20051298

PMCID:: PMC1386030

Article PDF–348K

Select item 121740613.

Structure and critical residues at the active site of spermidine/spermine-N1-acetyltransferase.

C S Coleman, H Huang, A E Pegg

Biochem J. 1996 Jun 15; 316(Pt 3): 697–701. doi: 10.1042/bj3160697

PMCID:: PMC1217406

Summary PDF–374K

Select item 121696214.

Differential transcription of the human spermidine/spermine N1-acetyltransferase (SSAT) gene in human lung carcinoma cells.

L Xiao, R A Casero, Jr

Biochem J. 1996 Jan 15; 313(Pt 2): 691–696. doi: 10.1042/bj3130691

PMCID:: PMC1216962

Summary PDF–362K

Select item 113177615.

High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma.

R A Casero, Jr, P Celano, S J Ervin, L Wiest, A E Pegg

Biochem J. 1990 Sep 15; 270(3): 615–620. doi: 10.1042/bj2700615

PMCID:: PMC1131776

Summary Page Browse PDF–1.6M

Select item 1039469116.

Loss-of-function variants in SAT1 cause X-linked Childhood-onset Systemic Lupus Erythematosus

Lingxiao Xu, Jian Zhao, Qing Sun, Xue Xu, Lei Wang, Ting Liu, Yunjuan Wu, Jingfeng Zhu, Linyu Geng, Yun Deng, Alexander Awgulewitsch, Diane L. Kamen, Jim C. Oates, Prithvi Raj, Edward K. Wakeland, R. Hal Scofield, Joel M. Guthridge, Judith A. James, Bevra H Hahn, Deborah K. McCurdy, Fang Wang, Miaojia Zhang, Wenfeng Tan, Gary S. Gilkeson, Betty P. Tsao

Ann Rheum Dis. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Ann Rheum Dis. 2022 Dec; 81(12): 1712–1721. Published online 2022 Aug 17. doi: 10.1136/ard-2022-222795

PMCID:: PMC10394691

Article PDF–1.8M

Select item 733751717.

Dengue virus targets RBM10 deregulating host cell splicing and innate immune response

Berta Pozzi, Laureano Bragado, Pablo Mammi, María Florencia Torti, Nicolás Gaioli, Leopoldo G Gebhard, Martín E García Solá, Rita Vaz-Drago, Néstor G Iglesias, Cybele C García, Andrea V Gamarnik, Anabella Srebrow

Nucleic Acids Res. 2020 Jul 9; 48(12): 6824–6838. Published online 2020 May 20. doi: 10.1093/nar/gkaa340

PMCID:: PMC7337517

Article PDF–3.5M

Select item 422909118.

Proximal Tubule Epithelial Cell Specific Ablation of the Spermidine/Spermine N¹-Acetyltransferase Gene Reduces the Severity of Renal Ischemia/Reperfusion Injury

Kamyar Zahedi, Sharon Barone, Yang Wang, Tracy Murray-Stewart, Prabir Roy-Chaudhury, Roger D. Smith, Robert A. Casero, Jr, Manoocher Soleimani

PLoS One. 2014; 9(11): e110161. Published online 2014 Nov 12. doi: 10.1371/journal.pone.0110161

PMCID:: PMC4229091

Article PDF–2.6M

Select item 331858719.

Polyamine-Regulated Translation of Spermidine/Spermine-N¹-Acetyltransferase

Oscar Perez-Leal, Carlos A. Barrero, Allen B. Clarkson, Robert A. Casero, Jr., Salim Merali

Mol Cell Biol. 2012 Apr; 32(8): 1453–1467. doi: 10.1128/MCB.06444-11

PMCID:: PMC3318587

Article PDF–3.2M

Select item 284006320.

The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines

Allison Pledgie-Tracy, Madhavi Billam, Amy Hacker, Michele D Sobolewski, Patrick M. Woster, Zhe Zhang, Robert A. Casero, Nancy E Davidson

Cancer Chemother Pharmacol. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Cancer Chemother Pharmacol. 2010 May; 65(6): 1067–1081. Published online 2009 Aug 30. doi: 10.1007/s00280-009-1112-8

PMCID:: PMC2840063

Article PDF–872K

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