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Items: 1 to 20 of 45

1.
Circ-GLI1 promotes metastasis in melanoma through interacting with p70S6K2 to activate Hedgehog/GLI1 and Wnt/β-catenin pathways and upregulate Cyr61
Jun Chen, Xiaobo Zhou, Jie Yang, Qilin Sun, Yang Liu, Ningli Li, Zhen Zhang, Hui Xu
Cell Death Dis. 2020 Jul; 11(7): 596. Published online 2020 Jul 30. doi: 10.1038/s41419-020-02799-x
PMCID:
PMC7393080
ArticlePDF–4.0M
2.
S6 Kinase2 Promotes Breast Cancer Cell Survival via Akt
Savitha Sridharan, Alakananda Basu
Cancer Res. Author manuscript; available in PMC 2012 Apr 1.
Published in final edited form as: Cancer Res. 2011 Apr 1; 71(7): 2590–2599. Published online 2011 Mar 22. doi: 10.1158/0008-5472.CAN-10-3253
PMCID:
PMC3070841
ArticlePDF–3.5M
3.
Regulation of catalytic activity of S6 kinase 2 during cell cycle
Derek Boyer, Rene Quintanilla, Kay K. Lee-Fruman
Mol Cell Biochem. Author manuscript; available in PMC 2008 Sep 29.
Published in final edited form as: Mol Cell Biochem. 2008 Jan; 307(1-2): 59–64. Published online 2007 Sep 5. doi: 10.1007/s11010-007-9584-5
PMCID:
PMC2556174
ArticlePDF–438K
4.
Up-Regulation of Phosphorylated/Activated p70 S6 Kinase and Its Relationship to Neurofibrillary Pathology in Alzheimer’s Disease
Wen-Lin An, Richard F. Cowburn, Lin Li, Heiko Braak, Irina Alafuzoff, Khalid Iqbal, Inge-Grundke Iqbal, Bengt Winblad, Jin-Jing Pei
Am J Pathol. 2003 Aug; 163(2): 591–607. doi: 10.1016/S0002-9440(10)63687-5
Correction in:
Am J Pathol. 2003 Dec; 163(6): 2645–2646.
PMCID:
PMC1868198
ArticlePDF–1.4M
5.
Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
Sopheap Phin, Deborah Kupferwasser, Joseph Lam, Kay K Lee-Fruman
Biochem J. 2003 Jul 15; 373(Pt 2): 583–591. doi: 10.1042/BJ20021794
PMCID:
PMC1223513
SummaryPDF–285K
6.
Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae
Abha Sahni, Hema P. Narra, Sanjeev K. Sahni
Int J Mol Sci. 2020 Oct; 21(19): 7179. Published online 2020 Sep 29. doi: 10.3390/ijms21197179
PMCID:
PMC7582468
ArticlePDF–1.9M
7.
Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2
Alakananda Basu, Savitha Sridharan
PLoS One. 2017; 12(3): e0173854. Published online 2017 Mar 16. doi: 10.1371/journal.pone.0173854
PMCID:
PMC5354308
ArticlePDF–1.4M
8.
S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells
Matthew J. Warner, Katherine S. Bridge, James P. Hewitson, Michael R. Hodgkinson, Alex Heyam, Bailey C. Massa, Jessica C. Haslam, Maria Chatzifrangkeskou, Gareth J.O. Evans, Michael J. Plevin, Tyson V. Sharp, Dimitris Lagos
Nucleic Acids Res. 2016 Nov 16; 44(20): 9942–9955. Published online 2016 Jul 12. doi: 10.1093/nar/gkw631
PMCID:
PMC5175334
ArticlePDF–7.3M
9.
The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer: a retrospective study including patients from the randomised Stockholm tamoxifen trials
Elin Karlsson, Gizeh Pérez-Tenorio, Risul Amin, Josefine Bostner, Lambert Skoog, Tommy Fornander, Dennis C Sgroi, Bo Nordenskjöld, Anna-Lotta Hallbeck, Olle Stål
Breast Cancer Res. 2013; 15(5): R96. Published online 2013 Oct 17. doi: 10.1186/bcr3557
PMCID:
PMC3978839
ArticlePDF–975K
10.
IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1
C-H Jia, M Li, J Liu, L Zhao, J Lin, P-L Lai, X Zhou, Y Zhang, Z-G Chen, H-Y Li, A-L Liu, C-L Yang, T-M Gao, Y Jiang, X-C Bai
Cell Death Differ. 2013 Feb; 20(2): 248–258. Published online 2012 Sep 7. doi: 10.1038/cdd.2012.115
PMCID:
PMC3554328
ArticlePDF–2.9M
11.
Protein Kinase C Phosphorylates Ribosomal Protein S6 Kinase βII and Regulates Its Subcellular Localization
Taras Valovka, Frederique Verdier, Rainer Cramer, Alexander Zhyvoloup, Timothy Fenton, Heike Rebholz, Mong-Lien Wang, Miechyslav Gzhegotsky, Alexander Lutsyk, Genadiy Matsuka, Valeriy Filonenko, Lijun Wang, Christopher G. Proud, Peter J. Parker, Ivan T. Gout
Mol Cell Biol. 2003 Feb; 23(3): 852–863. doi: 10.1128/MCB.23.3.852-863.2003
PMCID:
PMC140705
ArticlePDF–592K
12.
NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction
Chidiebere U Awah, Jan Winter, Claudiane M Mazdoom, Olorunseun O. Ogunwobi
Cancer Biol Ther. 2021; 22(10-12): 587–597. Published online 2021 Oct 27. doi: 10.1080/15384047.2021.1990631
PMCID:
PMC8726740
ArticlePDF–2.3M
13.
Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer
Savitha Sridharan, Alakananda Basu
Int J Mol Sci. 2020 Feb; 21(4): 1199. Published online 2020 Feb 11. doi: 10.3390/ijms21041199
PMCID:
PMC7072743
ArticlePDF–860K
14.
Involvement of Heterogeneous Ribonucleoprotein F in the Regulation of Cell Proliferation via the Mammalian Target of Rapamycin/S6 Kinase 2 Pathway
Eddy T. H. Goh, Olivier E. Pardo, Nicholas Michael, Andrew Niewiarowski, Nick Totty, Dariya Volkova, Irina R. Tsaneva, Michael J. Seckl, Ivan Gout
J Biol Chem. 2010 May 28; 285(22): 17065–17076. Published online 2010 Mar 22. doi: 10.1074/jbc.M109.078782
PMCID:
PMC2878046
ArticlePDF–1.7M
15.
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases
Brian Raught, Franck Peiretti, Anne-Claude Gingras, Mark Livingstone, David Shahbazian, Greg L Mayeur, Roberto D Polakiewicz, Nahum Sonenberg, John WB Hershey
EMBO J. 2004 Apr 21; 23(8): 1761–1769. Published online 2004 Apr 8. doi: 10.1038/sj.emboj.7600193
PMCID:
PMC394247
ArticlePDF–246K
16.
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
Patrick E. Burnett, Roxanne K. Barrow, Noam A. Cohen, Solomon H. Snyder, David M. Sabatini
Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4): 1432–1437. doi: 10.1073/pnas.95.4.1432
PMCID:
PMC19032
ArticlePDF–401K
17.
Degradation of Tiam1 by Casein Kinase 1 and the SCFβTrCP Ubiquitin Ligase Controls the Duration of mTOR-S6K Signaling
Roberto Magliozzi, Jihoon Kim, Teck Yew Low, Albert J. R. Heck, Daniele Guardavaccaro
J Biol Chem. 2014 Oct 3; 289(40): 27400–27409. Published online 2014 Aug 14. doi: 10.1074/jbc.M114.575571
PMCID:
PMC4183780
ArticlePDF–3.0M
18.
Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis
Caterina Nardella, Andrea Lunardi, Giuseppe Fedele, John G. Clohessy, Andrea Alimonti, Sara C. Kozma, George Thomas, Massimo Loda, Pier Paolo Pandolfi
Cancer Res. Author manuscript; available in PMC 2012 May 15.
Published in final edited form as: Cancer Res. 2011 May 15; 71(10): 3669–3675. Published online 2011 Mar 28. doi: 10.1158/0008-5472.CAN-10-3962
PMCID:
PMC3096749
ArticlePDF–1.0M
19.
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
David Shahbazian, Philippe P Roux, Virginie Mieulet, Michael S Cohen, Brian Raught, Jack Taunton, John W B Hershey, John Blenis, Mario Pende, Nahum Sonenberg
EMBO J. 2006 Jun 21; 25(12): 2781–2791. Published online 2006 Jun 8. doi: 10.1038/sj.emboj.7601166
PMCID:
PMC1500846
ArticlePDF–368K
20.
Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration
Joe Truong Nguyen, Connor Ray, Alexandra Lucienne Fox, Daniela Baccelli Mendonça, Jin Koo Kim, Paul H. Krebsbach
Sci Adv. 2018 May; 4(5): eaao5838. Published online 2018 May 9. doi: 10.1126/sciadv.aao5838
PMCID:
PMC5942914
ArticlePDF–2.8M

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