PMC Links for Gene (Select 5770) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 220

<< First< Prev

Page of 11

Next >Last >>

Select item 108333411.

High-resolution double vision of the allosteric phosphatase PTP1B

Shivani Sharma, Tamar Skaist Mehlman, Reddy Sudheer Sagabala, Benoit Boivin, Daniel A. Keedy

Acta Crystallogr F Struct Biol Commun. 2024 Jan 1; 80(Pt 1): 1–12. Published online 2024 Jan 1. doi: 10.1107/S2053230X23010749

PMCID:: PMC10833341

Article PDF–2.8M

Select item 103369612.

A Conserved Local Structural Motif Controls the Kinetics of PTP1B Catalysis

Christine Y. Yeh, Jesus A. Izaguirre, Jack B. Greisman, Lindsay Willmore, Paul Maragakis, David E. Shaw

J Chem Inf Model. 2023 Jul 10; 63(13): 4115–4124. Published online 2023 Jun 28. doi: 10.1021/acs.jcim.3c00286

PMCID:: PMC10336961

Article PDF–5.9M

Select item 95430243.

The role of PTP1B (PTPN1) in the prognosis of solid tumors: A meta-analysis

Jiupeng Zhou, Hui Guo, Yongfeng Zhang, Heng Liu, Quanli Dou

Medicine (Baltimore) 2022 Oct 7; 101(40): e30826. Published online 2022 Oct 7. doi: 10.1097/MD.0000000000030826

PMCID:: PMC9543024

Article PDF–1.9M

Select item 92663124.

Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma

Rongxing Liu, Yujie Sun, Jérémy Berthelet, Linh-Chi Bui, Ximing Xu, Mireille Viguier, Jean-Marie Dupret, Frédérique Deshayes, Fernando Rodrigues Lima

Int J Mol Sci. 2022 Jul; 23(13): 7060. Published online 2022 Jun 24. doi: 10.3390/ijms23137060

PMCID:: PMC9266312

Article PDF–2.0M

Select item 92151755.

Rapid degradation of protein tyrosine phosphatase 1B in sickle cells: Possible contribution to sickle cell membrane weakening

Panae Noomuna, John M. Hausman, Ruhani Sansoya, Theodosia Kalfa, Mary Risinger, Philip S. Low

FASEB J. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: FASEB J. 2022 Jun; 36(6): e22360. doi: 10.1096/fj.202100809RR

PMCID:: PMC9215175

Article PDF–1.0M

Select item 88069466.

Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation

Qiang Wang, Yuyan Pan, Liping Zhao, Fazhi Qi, Jiaqi Liu

Bioengineered. 2021; 12(1): 8396–8406. Published online 2021 Oct 25. doi: 10.1080/21655979.2021.1988376

PMCID:: PMC8806946

Article PDF–3.9M

Select item 87059047.

Structural Bases for Hesperetin Derivatives: Inhibition of Protein Tyrosine Phosphatase 1B, Kinetics Mechanism and Molecular Docking Study

Md Yousof Ali, Susoma Jannat, Hyun-Ah Jung, Jae-Sue Choi

Molecules. 2021 Dec; 26(24): 7433. Published online 2021 Dec 8. doi: 10.3390/molecules26247433

PMCID:: PMC8705904

Article PDF–3.3M

Select item 85089958.

Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation

Tomasz Kostrzewa, Karol Wołosewicz, Marek Jamrozik, Joanna Drzeżdżon, Julia Siemińska, Dagmara Jacewicz, Magdalena Górska-Ponikowska, Marcin Kołaczkowski, Ryszard Łaźny, Alicja Kuban-Jankowska

Int J Mol Sci. 2021 Oct; 22(19): 10368. Published online 2021 Sep 26. doi: 10.3390/ijms221910368

PMCID:: PMC8508995

Article PDF–3.2M

Select item 84737249.

Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling

Jennifer J Schwarz, Lorenz Grundmann, Thomas Kokot, Kathrin Kläsener, Sandra Fotteler, David Medgyesi, Maja Köhn, Michael Reth, Bettina Warscheid

Life Sci Alliance. 2021 Nov; 4(11): e202101084. Published online 2021 Sep 15. doi: 10.26508/lsa.202101084

PMCID:: PMC8473724

Article PDF–3.5M

Select item 830802110.

Indole- and Pyrazole-Glycyrrhetinic Acid Derivatives as PTP1B Inhibitors: Synthesis, In Vitro and In Silico Studies

Ledy De-la-Cruz-Martínez, Constanza Duran-Becerra, Martin González-Andrade, José C. Páez-Franco, Juan Manuel Germán-Acacio, Julio Espinosa-Chávez, J. Martin Torres-Valencia, Jaime Pérez-Villanueva, Juan Francisco Palacios-Espinosa, Olivia Soria-Arteche, Francisco Cortés-Benítez

Molecules. 2021 Jul; 26(14): 4375. Published online 2021 Jul 20. doi: 10.3390/molecules26144375

PMCID:: PMC8308021

Article PDF–2.4M

Select item 827148611.

Assessment of Antidiabetic Activity of the Shikonin by Allosteric Inhibition of Protein-Tyrosine Phosphatase 1B (PTP1B) Using State of Art: An In Silico and In Vitro Tactics

Mohd Saeed, Ambreen Shoaib, Munazzah Tasleem, Nadiyah M. Alabdallah, Md Jahoor Alam, Zeina El Asmar, Qazi Mohammad Sajid Jamal, Fevzi Bardakci, Saad S. Alqahtani, Irfan Ahmad Ansari, Riadh Badraoui

Molecules. 2021 Jul; 26(13): 3996. Published online 2021 Jun 30. doi: 10.3390/molecules26133996

PMCID:: PMC8271486

Article PDF–5.4M

Select item 808676512.

The PTP1B mutant PTP1B∆2–4 is a positive regulator of the JAK/STAT signalling pathway in Hodgkin lymphoma

Malena Zahn, Bianca Kaluszniak, Peter Möller, Ralf Marienfeld

Carcinogenesis. 2021 Apr; 42(4): 517–527. Published online 2020 Dec 31. doi: 10.1093/carcin/bgaa144

PMCID:: PMC8086765

Article PDF–738K

Select item 800566213.

The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy

Ting Huang, Xue Li, Fei Wang, Lihong Lu, Wenting Hou, Minmin Zhu, Changhong Miao

Cell Death Dis. 2021 Apr; 12(4): 333. Published online 2021 Mar 29. doi: 10.1038/s41419-021-03629-4

PMCID:: PMC8005662

Article PDF–2.9M

Select item 753592014.

Cooperative dynamics across distinct structural elements regulate PTP1B activity

Kristiane R. Torgeson, Michael W. Clarkson, Ganesan Senthil Kumar, Rebecca Page, Wolfgang Peti

J Biol Chem. 2020 Oct 2; 295(40): 13829–13837. Published online 2020 Jul 31. doi: 10.1074/jbc.RA120.014652

PMCID:: PMC7535920

Article PDF–1.8M

Select item 698254015.

Regulation of PTP1B activation through disruption of redox-complex formation

Avinash D. Londhe, Alexandre Bergeron, Stephanie M. Curley, Fuming Zhang, Keith D. Rivera, Akaash Kannan, Gérald Coulis, Syed H. M. Rizvi, Seung Jun Kim, Darryl J. Pappin, Nicholas K. Tonks, Robert J. Linhardt, Benoit Boivin

Nat Chem Biol. Author manuscript; available in PMC 2020 Jun 23.

Published in final edited form as: Nat Chem Biol. 2020 Feb; 16(2): 122–125. Published online 2019 Dec 23. doi: 10.1038/s41589-019-0433-0

PMCID:: PMC6982540

Article PDF–788K

Select item 691127616.

Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

Caroline E. Nunes-Xavier, Olaia Aurtenetxe, Laura Zaldumbide, Ricardo López-Almaraz, Asier Erramuzpe, Jesús M. Cortés, José I. López, Rafael Pulido

Diagn Pathol. 2019; 14: 134. Published online 2019 Dec 14. doi: 10.1186/s13000-019-0919-9

PMCID:: PMC6911276

Article PDF–1.2M

Select item 672122717.

Insight into the PTP1B Inhibitory Activity of Arylbenzofurans: An In Vitro and In Silico Study

Srijan Shrestha, Su Hui Seong, Seul Gi Park, Byung Sun Min, Hyun Ah Jung, Jae Sue Choi

Molecules. 2019 Aug; 24(16): 2893. Published online 2019 Aug 9. doi: 10.3390/molecules24162893

PMCID:: PMC6721227

Article PDF–1.7M

Select item 610028818.

High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans

Rita de Cássia Lemos Lima, Kenneth T. Kongstad, Lucília Kato, Marcos José das Silva, Henrik Franzyk, Dan Staerk

Molecules. 2018 Jul; 23(7): 1755. Published online 2018 Jul 17. doi: 10.3390/molecules23071755

PMCID:: PMC6100288

Article PDF–1.3M

Select item 603918119.

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering

Daniel A Keedy, Zachary B Hill, Justin T Biel, Emily Kang, T Justin Rettenmaier, José Brandão-Neto, Nicholas M Pearce, Frank von Delft, James A Wells, James S Fraser

eLife. 2018; 7: e36307. Published online 2018 Jun 7. doi: 10.7554/eLife.36307