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Select item 74431431.

ARNTL2 promotes pancreatic ductal adenocarcinoma progression through TGF/BETA pathway and is regulated by miR-26a-5p

Zhifang Wang, Tingting Liu, Wenhua Xue, Yuanyuan Fang, Xiaolong Chen, Lijun Xu, Lixia Zhang, Kelei Guan, Juntao Pan, Lili Zheng, Guijun Qin, Tingting Wang

Cell Death Dis. 2020 Aug; 11(8): 692. Published online 2020 Aug 10. doi: 10.1038/s41419-020-02839-6

PMCID:: PMC7443143

Abstract Article PDF–5.8M

Select item 48641242.

An Arntl2-driven secretome enables lung adenocarcinoma metastatic self-sufficiency

Jennifer J. Brady, Chen-Hua Chuang, Peyton G. Greenside, Zoë N. Rogers, Christopher W. Murray, Deborah R. Caswell, Ursula Hartmann, Andrew J. Connolly, E. Alejandro Sweet-Cordero, Anshul Kundaje, Monte M. Winslow

Cancer Cell. Author manuscript; available in PMC 2017 May 9.

Published in final edited form as: Cancer Cell. 2016 May 9; 29(5): 697–710. Published online 2016 Apr 14. doi: 10.1016/j.ccell.2016.03.003

PMCID:: PMC4864124

Abstract Article PDF–2.0M

Select item 25797963.

Genetic Differences in Human Circadian Clock Genes Among Worldwide Populations

Christopher M. Ciarleglio, Kelli Ryckman, Stein V. Servick, Akiko Hida, Sam Robbins, Nancy Wells, Jennifer Hicks, Sydney A. Larson, Joshua P. Wiedermann, Krista Carver, Nalo Hamilton, Kenneth K. Kidd, Judith R. Kidd, Jeffrey R. Smith, Jonathan Friedlaender, Douglas G. McMahon, Scott Williams, Marshall L. Summar, Carl Hirschie Johnson

J Biol Rhythms. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: J Biol Rhythms. 2008 Aug; 23(4): 330–340. doi: 10.1177/0748730408320284

PMCID:: PMC2579796

Abstract Article PDF–351K

Select item 67722804.

The Basic Helix-Loop-Helix-PAS Protein MOP9 Is a Brain-Specific Heterodimeric Partner of Circadian and Hypoxia Factors

John B. Hogenesch, Yi-Zhong Gu, Susan M. Moran, Kazuhiro Shimomura, Laurel A. Radcliffe, Joseph S. Takahashi, Christopher A. Bradfield

J Neurosci. 2000 Jul 1; 20(13): RC83. doi: 10.1523/JNEUROSCI.20-13-j0002.2000

PMCID:: PMC6772280

Abstract PDF–345K

Select item 43207595.

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

Michael J Parsons, Kathryn J Lester, Nicola L Barclay, Simon N Archer, Patrick M Nolan, Thalia C Eley, Alice M Gregory

J Sleep Res. 2014 Oct; 23(5): 595–604. Published online 2014 Mar 17. doi: 10.1111/jsr.12144

PMCID:: PMC4320759

Abstract Article PDF–322K

Select item 28488526.

ARNTL (BMAL1) and NPAS2 Gene Variants Contribute to Fertility and Seasonality

Leena Kovanen, Sirkku T. Saarikoski, Arpo Aromaa, Jouko Lönnqvist, Timo Partonen

PLoS One. 2010; 5(4): e10007. Published online 2010 Apr 2. doi: 10.1371/journal.pone.0010007

PMCID:: PMC2848852

Abstract Article PDF–100K

Select item 43482367.

Ube3a Imprinting Impairs Circadian Robustness in Angelman Syndrome Models

Shu-qun Shi, Terry Jo Bichell, Rebecca A. Ihrie, Carl Hirschie Johnson

Curr Biol. Author manuscript; available in PMC 2016 Mar 2.

Published in final edited form as: Curr Biol. 2015 Mar 2; 25(5): 537–545. Published online 2015 Feb 5. doi: 10.1016/j.cub.2014.12.047

PMCID:: PMC4348236

Abstract Article PDF–1010K

Select item 25748978.

Clock Genes may Influence Bipolar Disorder Susceptibility and Dysfunctional Circadian Rhythm

Jiajun Shi, Jacqueline K. Wittke-Thompson, Judith A. Badner, Eiji Hattori, James B. Potash, Virginia L Willour, Francis J. McMahon, Elliot S. Gershon, Chunyu Liu

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2008 Nov 5.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5; 147B(7): 1047–1055. doi: 10.1002/ajmg.b.30714

PMCID:: PMC2574897

Abstract Article PDF–82K

Select item 3438179.

Identification of a Novel Basic Helix-Loop-Helix-PAS Factor, NXF, Reveals a Sim2 Competitive, Positive Regulatory Role in Dendritic-Cytoskeleton Modulator Drebrin Gene Expression

Norihisa Ooe, Koichi Saito, Nobuyoshi Mikami, Iwao Nakatuka, Hideo Kaneko

Mol Cell Biol. 2004 Jan; 24(2): 608–616. doi: 10.1128/MCB.24.2.608-616.2004

PMCID:: PMC343817

Abstract Article PDF–599K

Select item 275721810.

Preferential Inhibition of BMAL2-CLOCK Activity by PER2 Reemphasizes Its Negative Role and a Positive Role of BMAL2 in the Circadian Transcription

Momoko Sasaki, Hikari Yoshitane, Ngoc-Hien Du, Toshiyuki Okano, Yoshitaka Fukada

J Biol Chem. 2009 Sep 11; 284(37): 25149–25159. Published online 2009 Jul 15. doi: 10.1074/jbc.M109.040758

PMCID:: PMC2757218

Abstract Article PDF–2.4M

Select item 113391311.

Expression of the gene for Dec2, a basic helix–loop–helix transcription factor, is regulated by a molecular clock system

Hidenori Hamaguchi, Katsumi Fujimoto, Takeshi Kawamoto, Mitsuhide Noshiro, Koji Maemura, Norihiko Takeda, Ryozo Nagai, Masae Furukawa, Sato Honma, Ken-ichi Honma, Hidemi Kurihara, Yukio Kato

Biochem J. 2004 Aug 15; 382(Pt 1): 43–50. Prepublished online 2004 May 17. Published online 2004 Aug 10. doi: 10.1042/BJ20031760

PMCID:: PMC1133913

Abstract Article PDF–519K

Select item 285410612.

Louise K Sjöholm, Leena Kovanen, Sirkku T Saarikoski, Martin Schalling, Catharina Lavebratt, Timo Partonen

J Circadian Rhythms. 2010; 8: 1. Published online 2010 Jan 21. doi: 10.1186/1740-3391-8-1

PMCID:: PMC2854106

Abstract Article PDF–288K

Select item 282377013.

Systematic Analysis of Circadian Genes in a Population-Based Sample Reveals Association of TIMELESS with Depression and Sleep Disturbance

Siddheshwar J. Utge, Pia Soronen, Anu Loukola, Erkki Kronholm, Hanna M. Ollila, Sami Pirkola, Tarja Porkka-Heiskanen, Timo Partonen, Tiina Paunio

PLoS One. 2010; 5(2): e9259. Published online 2010 Feb 18. doi: 10.1371/journal.pone.0009259

PMCID:: PMC2823770

Abstract Article PDF–159K

Select item 269714114.

NPAS2 and PER2 are linked to risk factors of the metabolic syndrome

Ani Englund, Leena Kovanen, Sirkku T Saarikoski, Jari Haukka, Antti Reunanen, Arpo Aromaa, Jouko Lönnqvist, Timo Partonen

J Circadian Rhythms. 2009; 7: 5. Published online 2009 May 26. doi: 10.1186/1740-3391-7-5

PMCID:: PMC2697141

Abstract Article PDF–679K

Select item 305533715.

Differential Association of Circadian Genes with Mood Disorders: CRY1 and NPAS2 are Associated with Unipolar Major Depression and CLOCK and VIP with Bipolar Disorder

Virginia Soria, Èrika Martínez-Amorós, Geòrgia Escaramís, Joaquín Valero, Rosario Pérez-Egea, Cecilia García, Alfonso Gutiérrez-Zotes, Dolors Puigdemont, Mònica Bayés, José M Crespo, Lourdes Martorell, Elisabet Vilella, Antonio Labad, Julio Vallejo, Víctor Pérez, José M Menchón, Xavier Estivill, Mònica Gratacòs, Mikel Urretavizcaya

Neuropsychopharmacology. 2010 May; 35(6): 1279–1289. Published online 2010 Jan 13. doi: 10.1038/npp.2009.230

PMCID:: PMC3055337

Abstract Article PDF–415K

Select item 340189916.

Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia

Hader A Mansour, Michael E Talkowski, Joel Wood, Kodavali V Chowdari, Lora McClain, Konasale Prasad, Debra Montrose, Andrea Fagiolini, Edward S Friedman, Michael H Allen, Charles L Bowden, Joseph Calabrese, Rif S El-Mallakh, Michael Escamilla, Stephen V Faraone, Mark D Fossey, Laszlo Gyulai, Jennifer M Loftis, Peter Hauser, Terence A Ketter, Lauren B Marangell, David J Miklowitz, Andrew A Nierenberg, Jayendra Patel, Gary S Sachs, Pamela Sklar, Jordan W Smoller, Nan Laird, Matcheri Keshavan, Michael E Thase, David Axelson, Boris Birmaher, David Lewis, Tim Monk, Ellen Frank, David J Kupfer, Bernie Devlin, Vishwajit L Nimgaonkar

Bipolar Disord. Author manuscript; available in PMC 2012 Jul 23.

Published in final edited form as: Bipolar Disord. 2009 Nov; 11(7): 701–710. doi: 10.1111/j.1399-5618.2009.00756.x

PMCID:: PMC3401899

Abstract Article PDF–305K

Select item 361082017.

Dynamic Circadian Protein–Protein Interaction Networks Predict Temporal Organization of Cellular Functions

Thomas Wallach, Katja Schellenberg, Bert Maier, Ravi Kiran Reddy Kalathur, Pablo Porras, Erich E. Wanker, Matthias E. Futschik, Achim Kramer

PLoS Genet. 2013 Mar; 9(3): e1003398. Published online 2013 Mar 28. doi: 10.1371/journal.pgen.1003398

PMCID:: PMC3610820

Abstract Article PDF–6.3M

Select item 381740418.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 399653719.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 804593220.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

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