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Select item 66923691.

Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns

Sandra Keiper, Panagiotis Papasaikas, Cindy L. Will, Juan Valcárcel, Cyrille Girard, Reinhard Lührmann

Nat Commun. 2019; 10: 3639. Published online 2019 Aug 13. doi: 10.1038/s41467-019-11293-8

PMCID:: PMC6692369

Article PDF–5.5M

Select item 65612112.

Destabilization of the human RED–SMU1 splicing complex as a basis for host-directed antiinfluenza strategy

Usama Ashraf, Laura Tengo, Laurent Le Corre, Guillaume Fournier, Patricia Busca, Andrew A. McCarthy, Marie-Anne Rameix-Welti, Christine Gravier-Pelletier, Rob W. H. Ruigrok, Yves Jacob, Pierre-Olivier Vidalain, Nicolas Pietrancosta, Thibaut Crépin, Nadia Naffakh

Proc Natl Acad Sci U S A. 2019 May 28; 116(22): 10968–10977. Published online 2019 May 10. doi: 10.1073/pnas.1901214116

PMCID:: PMC6561211

Article PDF–1.7M

Select item 40557413.

Recruitment of RED-SMU1 Complex by Influenza A Virus RNA Polymerase to Control Viral mRNA Splicing

Guillaume Fournier, Chiayn Chiang, Sandie Munier, Andru Tomoiu, Caroline Demeret, Pierre-Olivier Vidalain, Yves Jacob, Nadia Naffakh

PLoS Pathog. 2014 Jun; 10(6): e1004164. Published online 2014 Jun 12. doi: 10.1371/journal.ppat.1004164

Correction in:: PLoS Pathog. 2014 Jul; 10(7): e1004317.

PMCID:: PMC4055741

Article PDF–2.8M

Select item 91288184.

Biallelic FRA10AC1 variants cause a neurodevelopmental disorder with growth retardation

Leonie von Elsner, Guoliang Chai, Pauline E Schneeberger, Frederike L Harms, Christian Casar, Minyue Qi, Malik Alawi, Ghada M H Abdel-Salam, Maha S Zaki, Florian Arndt, Xiaoxu Yang, Valentina Stanley, Maja Hempel, Joseph G Gleeson, Kerstin Kutsche

Brain. 2022 Apr; 145(4): 1551–1563. Published online 2021 Oct 25. doi: 10.1093/brain/awab403

PMCID:: PMC9128818

Article PDF–1013K

Select item 71985255.

Deubiquitinase USP47-stabilized splicing factor IK regulates the splicing of ATM pre-mRNA

Hye In Ka, Sunyi Lee, Sora Han, Ae Lee Jeong, Ji Young Park, Hyun Jeong Joo, Su Jung Soh, Doyeon Park, Young Yang

Cell Death Discov. 2020; 6: 34. Published online 2020 May 4. doi: 10.1038/s41420-020-0268-1

PMCID:: PMC7198525

Article PDF–2.1M

Select item 872256.

Analysis of smu-1, a Gene That Regulates the Alternative Splicing of unc-52 Pre-mRNA in Caenorhabditis elegans

Caroline A. Spike, Jocelyn E. Shaw, Robert K. Herman

Mol Cell Biol. 2001 Aug; 21(15): 4985–4995. doi: 10.1128/MCB.21.15.4985-4995.2001

PMCID:: PMC87225

Article PDF–393K

Select item 59638467.

CRL7^SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression

Varun Jayeshkumar Shah, Subbareddy Maddika

J Cell Sci. 2018 Apr 15; 131(8): jcs213868. Published online 2018 Apr 26. doi: 10.1242/jcs.213868

PMCID:: PMC5963846

Article

Select item 70424858.

Gain-of-Function MN1 Truncation Variants Cause a Recognizable Syndrome with Craniofacial and Brain Abnormalities

Noriko Miyake, Hidehisa Takahashi, Kazuyuki Nakamura, Bertrand Isidor, Yoko Hiraki, Eriko Koshimizu, Masaaki Shiina, Kazunori Sasaki, Hidefumi Suzuki, Ryota Abe, Yayoi Kimura, Tomoko Akiyama, Shin-ichi Tomizawa, Tomonori Hirose, Kohei Hamanaka, Satoko Miyatake, Satomi Mitsuhashi, Takeshi Mizuguchi, Atsushi Takata, Kazuyuki Obo, Mitsuhiro Kato, Kazuhiro Ogata, Naomichi Matsumoto

Am J Hum Genet. 2020 Jan 2; 106(1): 13–25. Published online 2019 Dec 12. doi: 10.1016/j.ajhg.2019.11.011

PMCID:: PMC7042485

Article PDF–1.9M

Select item 55828279.

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle

Taner Dogan, Florian Gnad, Jocelyn Chan, Lilian Phu, Amy Young, Mark J. Chen, Sophia Doll, Matthew P. Stokes, Marcia Belvin, Lori S. Friedman, Donald S. Kirkpatrick, Klaus P. Hoeflich, Georgia Hatzivassiliou

J Biol Chem. 2017 Sep 1; 292(35): 14311–14324. Published online 2017 Jun 27. doi: 10.1074/jbc.M117.792754

PMCID:: PMC5582827

Article PDF–2.0M

Select item 887529710.

CRL4^AMBRA1 is a master regulator of D-type cyclins

Daniele Simoneschi, Gergely Rona, Nan Zhou, Yeon-Tae Jeong, Shaowen Jiang, Giacomo Milletti, Arnaldo A. Arbini, Alfie O’Sullivan, Andrew A. Wang, Sorasicha Nithikasem, Sarah Keegan, Yik Siu, Valentina Cianfanelli, Emiliano Maiani, Francesca Nazio, Francesco Cecconi, Francesco Boccalatte, David Fenyö, Drew R. Jones, Luca Busino, Michele Pagano

Nature. Author manuscript; available in PMC 2022 Apr 14.

Published in final edited form as: Nature. 2021 Apr; 592(7856): 789–793. Published online 2021 Apr 14. doi: 10.1038/s41586-021-03445-y

PMCID:: PMC8875297

Article PDF–6.0M

Select item 720609911.

The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53

Chen Hu, Mu Zhang, Niko Moses, Cong-li Hu, Lisa Polin, Wei Chen, Hyejeong Jang, Joshua Heyza, Agnes Malysa, Joseph A. Caruso, Shengyan Xiang, Steve Patrick, Paul Stemmer, Zhenkun Lou, Wenlong Bai, Chuangui Wang, Gerold Bepler, Xiaohong Mary Zhang

Cell Death Dis. 2020 May; 11(5): 328. Published online 2020 May 7. doi: 10.1038/s41419-020-2519-8

PMCID:: PMC7206099

Article PDF–2.1M

Select item 440166212.

FBXW7 modulates cellular stress response and metastatic potential via HSF1 post-translational modification

Nikos Kourtis, Rana S. Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T. Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt, Emily I. Chen, Julide T. Celebi, Charalampos Lazaris, Aristotelis Tsirigos, Iman Osman, Eva Hernando, Iannis Aifantis

Nat Cell Biol. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Cell Biol. 2015 Mar; 17(3): 322–332. doi: 10.1038/ncb3121

PMCID:: PMC4401662

Article PDF–5.0M

Select item 818479613.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Article PDF–2.4M

Select item 951327114.

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin

J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379

PMCID:: PMC9513271

Article PDF–2.7M

Select item 934647115.

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2‐mediated degradation

Mi Chen, Shreyas Lingadahalli, Nitin Narwade, Kate Man Kei Lei, Shanshan Liu, Zuxianglan Zhao, Yimin Zheng, Qian Lu, Alexander Hin Ning Tang, Terence Chuen Wai Poon, Edwin Cheung

EMBO Rep. 2022 Aug; 23(8): e53468. Published online 2022 Jul 4. doi: 10.15252/embr.202153468

PMCID:: PMC9346471

Article PDF–5.2M

Select item 274057216.

A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication

Man Lung Yeung, Laurent Houzet, Venkat S. R. K. Yedavalli, Kuan-Teh Jeang

J Biol Chem. 2009 Jul 17; 284(29): 19463–19473. Published online 2009 May 20. doi: 10.1074/jbc.M109.010033

PMCID:: PMC2740572

Article PDF–2.5M

Select item 632118517.

High Throughput Chemical Screening Reveals Multiple Regulatory Proteins on FOXA1 in Breast Cancer Cell Lines

Shixiong Wang, Sachin Kumar Singh, Madhumohan R. Katika, Sandra Lopez-Aviles, Antoni Hurtado

Int J Mol Sci. 2018 Dec; 19(12): 4123. Published online 2018 Dec 19. doi: 10.3390/ijms19124123

PMCID:: PMC6321185

Article PDF–2.8M

Select item 1094570718.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Article PDF–2.8M

Select item 599379719.

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins

Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki, Jaya Gangopadhyay, Steven P. Gygi, Robin Reed

Sci Rep. 2018; 8: 8755. Published online 2018 Jun 8. doi: 10.1038/s41598-018-27136-3

PMCID:: PMC5993797

Article PDF–2.9M

Select item 660120820.

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

Manal Alsulami, Nayla Munawar, Eugene Dillon, Giorgio Oliviero, Kieran Wynne, Mona Alsolami, Catherine Moss, Peadar Ó Gaora, Fergal O'Meara, David Cotter, Gerard Cagney

Mol Cell Proteomics. 2019 Jul; 18(7): 1428–1436. Published online 2019 May 10. doi: 10.1074/mcp.RA119.001518

PMCID:: PMC6601208

Article PDF–1.8M

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