PMC Links for Gene (Select 5426) - PMC

Links from Gene

Items: 1 to 20 of 153

<< First< Prev

Page of 8

Select item 107969171.

The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway

Ming Tang, Shasha Yin, Hongliang Zeng, Ao Huang, Yujia Huang, Zhiyi Hu, Ab Rauf Shah, Shuyong Zhang, Haisen Li, Guofang Chen

Cell Death Dis. 2024 Jan; 15(1): 69. Published online 2024 Jan 18. doi: 10.1038/s41419-023-06418-3

PMCID:: PMC10796917

Article PDF–9.8M

Select item 107564812.

Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer

IKUMI KITAZONO, TOSHIAKI AKAHANE, SEIYA YOKOYAMA, EMI KUBOTA, YUKARI NISHIDA-KIRITA, HIROTSUGU NOGUCHI, MIKI MURAKAMI, SHINTARO YANAZUME, HIROAKI KOBAYASHI, AKIHIDE TANIMOTO

In Vivo. 2024 Jan-Feb; 38(1): 321–333. Published online 2024 Jan 3. doi: 10.21873/invivo.13442

PMCID:: PMC10756481

Article PDF–3.6M

Select item 106100223.

Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants

Janick Selves, Helena de Castro e Gloria, Anne-Cécile Brunac, Jenifer Saffi, Rosine Guimbaud, Pierre Brousset, Jean-Sébastien Hoffmann

Life Sci Alliance. 2024 Jan; 7(1): e202302290. Published online 2023 Oct 27. doi: 10.26508/lsa.202302290

PMCID:: PMC10610022

Article PDF–1.2M

Select item 95819784.

The iron-sulfur cluster is essential for DNA binding by human DNA polymerase ε

Alisa E. Lisova, Andrey G. Baranovskiy, Lucia M. Morstadt, Nigar D. Babayeva, Elena I. Stepchenkova, Tahir H. Tahirov

Sci Rep. 2022; 12: 17436. Published online 2022 Oct 19. doi: 10.1038/s41598-022-21550-4

PMCID:: PMC9581978

Article PDF–1.6M

Select item 92608395.

Pathological complete response to immune checkpoint inhibitor in patients with colorectal cancer liver metastases harboring POLE exonuclease domain mutation

Lei Wen, Zhigang Chen, Xiaomeng Ji, William Pat Fong, Qiong Shao, Chao Ren, Yanyu Cai, Binkui Li, Yunfei Yuan, Deshen Wang, Yuhong Li

J Immunother Cancer. 2022; 10(7): e004487. Published online 2022 Jul 6. doi: 10.1136/jitc-2022-004487

PMCID:: PMC9260839

Article PDF–3.3M

Select item 92058886.

Efficient discrimination against RNA-containing primers by human DNA polymerase ε

Alisa E. Lisova, Andrey G. Baranovskiy, Lucia M. Morstadt, Nigar D. Babayeva, Tahir H. Tahirov

Sci Rep. 2022; 12: 10163. Published online 2022 Jun 17. doi: 10.1038/s41598-022-14602-2

PMCID:: PMC9205888

Article PDF–1.6M

Select item 90241877.

Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study

Shuangni Yu, Zezheng Sun, Liju Zong, Jie Yan, Mei Yu, Jie Chen, Zhaohui Lu

J Gynecol Oncol. 2022 May; 33(3): e38. Published online 2022 Feb 3. doi: 10.3802/jgo.2022.33.e38

PMCID:: PMC9024187

Article PDF–2.7M

Select item 88274428.

The clinicopathology and survival characteristics of patients with POLE proofreading mutations in endometrial carcinoma: A systematic review and meta-analysis

Alaa Salah Jumaah, Hawraa Sahib Al-Haddad, Katherine Ann McAllister, Akeel Abed Yasseen

PLoS One. 2022; 17(2): e0263585. Published online 2022 Feb 9. doi: 10.1371/journal.pone.0263585

PMCID:: PMC8827442

Article PDF–1.2M

Select item 88209279.

Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers

Benjamin Garmezy, Jinesh Gheeya, Heather Y. Lin, Yuefan Huang, Taebeom Kim, Xianli Jiang, Kyaw Z. Thein, Patrick G. Pilié, Fadl Zeineddine, Wanlin Wang, Kenna R. Shaw, Jordi Rodon, John Paul Shen, Ying Yuan, Funda Meric-Bernstam, Ken Chen, Timothy A. Yap

JCO Precis Oncol. 2022 Feb; 6: e2100267. Published online 2022 Feb 2. doi: 10.1200/PO.21.00267

PMCID:: PMC8820927

Article PDF–1.1M

Select item 849142410.

Distinct mutational profile and immune microenvironment in microsatellite-unstable and POLE-mutated tumors

Hee Sang Hwang, Deokhoon Kim, Jene Choi

J Immunother Cancer. 2021; 9(10): e002797. Published online 2021 Oct 3. doi: 10.1136/jitc-2021-002797

PMCID:: PMC8491424

Article PDF–5.6M

Select item 817775711.

POLE mutation spectra are shaped by the mutant allele identity, its abundance and mismatch repair status

Karl P. Hodel, Meijuan J.S. Sun, Nathan Ungerleider, Vivian S. Park, Leonard G. Williams, David L. Bauer, Victoria E. Immethun, Jieqiong Wang, Zucai Suo, Hua Lu, James B. McLachlan, Zachary F. Pursell

Mol Cell. Author manuscript; available in PMC 2021 Jun 18.

Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1166–1177.e6. Published online 2020 Jun 3. doi: 10.1016/j.molcel.2020.05.012

PMCID:: PMC8177757

Article PDF–2.1M

Select item 814665012.

Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations

Takashi Kawai, Akihiro Nyuya, Yoshiko Mori, Takehiro Tanaka, Hiroaki Tanioka, Kazuya Yasui, Toshiaki Toshima, Fumitaka Taniguchi, Kunitoshi Shigeyasu, Yuzo Umeda, Toshiyoshi Fujiwara, Makoto Okawaki, Yoshiyuki Yamaguchi, Ajay Goel, Takeshi Nagasaka

Clin Epigenetics. 2021; 13: 117. Published online 2021 May 25. doi: 10.1186/s13148-021-01104-7

PMCID:: PMC8146650

Article PDF–1.4M

Select item 715631213.

ENDOMETRIAL CARCINOMAS WITH A “SEROUS” COMPONENT IN YOUNG WOMEN ARE ENRICHED FOR DNA MISMATCH REPAIR DEFICIENCY, LYNCH SYNDROME, AND POLE EXONUCLEASE DOMAIN MUTATIONS

Niamh Conlon, Arnaud Da Cruz Paula, Charles W. Ashley, Sheila Segura, Louise De Brot, Edaise M. da Silva, Robert A. Soslow, Britta Weigelt, Deborah F. DeLair

Am J Surg Pathol. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Am J Surg Pathol. 2020 May; 44(5): 641–648. doi: 10.1097/PAS.0000000000001461

PMCID:: PMC7156312

Article PDF–2.6M

Select item 703474814.

Clinicopathological characteristics and prognostic value of POLE mutations in endometrial cancer: A systematic review and meta-analysis

Ya He, Tian Wang, Na Li, Binkai Yang, Yuanjing Hu

Medicine (Baltimore) 2020 Feb; 99(8): e19281. Published online 2020 Feb 21. doi: 10.1097/MD.0000000000019281

PMCID:: PMC7034748

Article PDF–1.3M

Select item 698065115.

CLINICAL OUTCOMES OF PATIENTS WITH POLE MUTATED ENDOMETRIOID ENDOMETRIAL CANCER

Marina Stasenko, Irina Tunnage, Charles W. Ashley, Maria M. Rubinstein, Alicia J. Latham, Arnaud Da Cruz Paula, Jennifer J. Mueller, Mario M. Leitao, Jr., Claire F. Friedman, Vicky Makker, Robert A. Soslow, Deborah F. DeLair, David M. Hyman, Dimitriy Zamarin, Kaled M. Alektiar, Carol A. Aghajanian, Nadeem R. Abu-Rustum, Britta Weigelt, Karen A. Cadoo

Gynecol Oncol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Gynecol Oncol. 2020 Jan; 156(1): 194–202. Published online 2019 Nov 19. doi: 10.1016/j.ygyno.2019.10.028

PMCID:: PMC6980651

Article PDF–563K

Select item 692586916.

POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction

Yiran Li, Yiding Bian, Kai Wang, Xiao-Ping Wan

BMC Med Genet. 2019; 20: 202. Published online 2019 Dec 21. doi: 10.1186/s12881-019-0936-2

PMCID:: PMC6925869

Article PDF–2.3M

Select item 671244817.

Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene

Hitoshi Hino, Akio Shiomi, Masatoshi Kusuhara, Hiroyasu Kagawa, Yushi Yamakawa, Keiichi Hatakeyama, Takanori Kawabata, Takuma Oishi, Kenichi Urakami, Takeshi Nagashima, Yusuke Kinugasa, Ken Yamaguchi

Cancer Med. 2019 Aug; 8(10): 4587–4597. Published online 2019 Jun 25. doi: 10.1002/cam4.2344

PMCID:: PMC6712448

Article PDF–450K

Select item 643674518.

Phenotype of POLE-mutated endometrial cancer

Sara Imboden, Denis Nastic, Mehran Ghaderi, Filippa Rydberg, Tilman T. Rau, Michael D. Mueller, Elisabeth Epstein, Joseph W. Carlson

PLoS One. 2019; 14(3): e0214318. Published online 2019 Mar 27. doi: 10.1371/journal.pone.0214318

PMCID:: PMC6436745

Article PDF–672K

Select item 628841319.

DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency

Clare V. Logan, Jennie E. Murray, David A. Parry, Andrea Robertson, Roberto Bellelli, Žygimantė Tarnauskaitė, Rachel Challis, Louise Cleal, Valerie Borel, Adeline Fluteau, Javier Santoyo-Lopez, SGP Consortium, Tim Aitman, Inês Barroso, Donald Basel, Louise S. Bicknell, Himanshu Goel, Hao Hu, Chad Huff, Michele Hutchison, Caroline Joyce, Rachel Knox, Amy E. Lacroix, Sylvie Langlois, Shawn McCandless, Julie McCarrier, Kay A. Metcalfe, Rose Morrissey, Nuala Murphy, Irène Netchine, Susan M. O’Connell, Ann Haskins Olney, Nandina Paria, Jill A. Rosenfeld, Mark Sherlock, Erin Syverson, Perrin C. White, Carol Wise, Yao Yu, Margaret Zacharin, Indraneel Banerjee, Martin Reijns, Michael B. Bober, Robert K. Semple, Simon J. Boulton, Jonathan J. Rios, Andrew P. Jackson

Am J Hum Genet. 2018 Dec 6; 103(6): 1038–1044. Published online 2018 Nov 29. doi: 10.1016/j.ajhg.2018.10.024

PMCID:: PMC6288413

Article PDF–1.0M

Select item 605694920.

Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-gene Panels: Beyond BRCA1/2

Kyung Jin Eoh, Ji Eun Kim, Hyung Seok Park, Seung-Tae Lee, Ji Soo Park, Jung Woo Han, Jung-Yun Lee, Sunghoon Kim, Sang Wun Kim, Jae Hoon Kim, Young Tae Kim, Eun Ji Nam

Cancer Res Treat. 2018 Jul; 50(3): 917–925. Published online 2017 Sep 27. doi: 10.4143/crt.2017.220

PMCID:: PMC6056949

Article PDF–616K

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 153

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity