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Select item 105824281.

PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti‐PD‐1 Immunotherapy

Yimin Zheng, Yining Wang, Zhou Lu, Jinkai Wan, Lulu Jiang, Danjun Song, Chuanyuan Wei, Chao Gao, Guoming Shi, Jian Zhou, Jia Fan, Aiwu Ke, Lu Zhou, Jiabin Cai

Adv Sci (Weinh) 2023 Oct; 10(29): 2301928. Published online 2023 Sep 14. doi: 10.1002/advs.202301928

PMCID:: PMC10582428

Abstract Article PDF–5.7M

Select item 72214332.

Circ‐PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR‐542‐3p/CDC5L/PEAK1 pathway

Chunmei Zhang, Yang Li, Wancheng Zhao, Guipeng Liu, Qing Yang

Cancer Med. 2020 May; 9(10): 3500–3521. Published online 2020 Mar 13. doi: 10.1002/cam4.2929

PMCID:: PMC7221433

Abstract Article PDF–4.9M

Select item 58581043.

Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion

Yao-An Wen, Bo-Wei Zhou, Dao-Jun Lv, Fang-Peng Shu, Xian-Lu Song, Bin Huang, Chong Wang, Shan-Chao Zhao

Asian J Androl. 2018 Mar-Apr; 20(2): 178–183. Published online 2017 Dec 22. doi: 10.4103/aja.aja_57_17

PMCID:: PMC5858104

Abstract Article PDF–1.6M

Select item 57191554.

Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1

Shi-en Liu, Jun-chi Hu, Hao Zhang, Pan Xu, Wei Wan, Ming-yue Zheng, Kun-qian Yu, Hong Ding, Hua-liang Jiang, Lu Zhou, Cheng Luo

Acta Pharmacol Sin. 2017 Dec; 38(12): 1673–1682. Published online 2017 Jul 27. doi: 10.1038/aps.2017.37

PMCID:: PMC5719155

Abstract Article PDF–2.0M

Select item 56054425.

Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate

Rob C. Oslund, Xiaoyang Su, Michael Haugbro, Jung-Min Kee, Mark Esposito, Yael David, Boyuan Wang, Eva Ge, David H. Perlman, Yibin Kang, Tom W. Muir, Joshua D. Rabinowitz

Nat Chem Biol. Author manuscript; available in PMC 2018 Feb 7.

Published in final edited form as: Nat Chem Biol. 2017 Oct; 13(10): 1081–1087. Published online 2017 Aug 7. doi: 10.1038/nchembio.2453

PMCID:: PMC5605442

Abstract Article PDF–1.3M

Select item 53553286.

Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth

Yan Wang, Wen-Sheng Cai, Luonan Chen, Guanyu Wang

Oncotarget. 2017 Feb 14; 8(7): 12093–12107. Published online 2017 Jan 5. doi: 10.18632/oncotarget.14517

PMCID:: PMC5355328

Abstract Article PDF–5.3M

Select item 52947847.

Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells

Jia Qu, Wenyi Sun, Jie Zhong, Hao Lv, Mingrui Zhu, Jun Xu, Nan Jin, Zuoquan Xie, Minjia Tan, Shu-Hai Lin, Meiyu Geng, Jian Ding, Min Huang

J Cell Biol. 2017 Feb; 216(2): 409–424. doi: 10.1083/jcb.201607008

Correction in:: J Cell Biol. 2017 Aug 7; 216(8): 2597–2598.

PMCID:: PMC5294784

Abstract Article PDF–3.4M

Select item 45839288.

Expression of PGAM1 in renal clear cell carcinoma and its clinical significance

Chunjing Li, Fangpeng Shu, Bin Lei, Daojun Lv, Shoubo Zhang, Xiangming Mao

Int J Clin Exp Pathol. 2015; 8(8): 9410–9415. Published online 2015 Aug 1.

PMCID:: PMC4583928

Abstract Article PDF–587K

Select item 36488829.

Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

Taro Hitosugi, Lu Zhou, Jun Fan, Shannon Elf, Liang Zhang, Jianxin Xie, Yi Wang, Ting-Lei Gu, Masa Aleckovic, Gary LeRoy, Yibin Kang, Hee-Bum Kang, Jae-Ho Seo, Changliang Shan, Peng Jin, Weimin Gong, Sagar Lonial, Martha L. Arellano, Hanna J. Khoury, Georgia Z. Chen, Dong M. Shin, Fadlo R. Khuri, Titus J. Boggon, Sumin Kang, Chuan He, Jing Chen

Nat Commun. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Nat Commun. 2013; 4: 1790. doi: 10.1038/ncomms2759

PMCID:: PMC3648882

Abstract Article PDF–1.9M

Select item 350052410.

Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth

Taro Hitosugi, Lu Zhou, Shannon Elf, Jun Fan, Hee-Bum Kang, Jae Ho Seo, Changliang Shan, Qing Dai, Liang Zhang, Jianxin Xie, Ting-Lei Gu, Peng Jin, Masa Aleckovic, Gary LeRoy, Yibin Kang, Jessica A. Sudderth, Ralph J. DeBerardinis, Chi-Hao Luan, Georgia Z. Chen, Susan Muller, Dong M. Shin, Taofeek K. Owonikoko, Sagar Lonial, Martha L. Arellano, Hanna J. Khoury, Fadlo R. Khuri, Benjamin H. Lee, Keqiang Ye, Titus J. Boggon, Sumin Kang, Chuan He, Jing Chen

Cancer Cell. Author manuscript; available in PMC 2013 Nov 13.

Published in final edited form as: Cancer Cell. 2012 Nov 13; 22(5): 585–600. doi: 10.1016/j.ccr.2012.09.020

PMCID:: PMC3500524

Abstract Article PDF–4.3M

Select item 287343811.

Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

Fenglian Ren, Hong Wu, Yunlong Lei, Haiyuan Zhang, Rui Liu, Yong Zhao, Xiancheng Chen, Dequan Zeng, Aiping Tong, Lijuan Chen, Yuquan Wei, Canhua Huang

Mol Cancer. 2010; 9: 81. Published online 2010 Apr 19. doi: 10.1186/1476-4598-9-81

PMCID:: PMC2873438

Abstract Article PDF–1.7M

Select item 176254912.

Phosphoglyceric acid mutase: rare genetic variants and tissue distribution.

S H Chen, J Anderson, E R Giblett, M Lewis

Am J Hum Genet. 1974 Jan; 26(1): 73–77.

PMCID:: PMC1762549

Summary Page Browse PDF–517K

Select item 1071954013.

RFX6 facilitates aerobic glycolysis‐mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1

Zhiyu Qiu, Chenwei Wang, Pinzhu Huang, Yichuan Yuan, Yunxing Shi, Zhu Lin, Zhenkun Huang, Dinglan Zuo, Jiliang Qiu, Wei He, Jingxian Shen, Yi Niu, Yunfei Yuan, Binkui Li

Clin Transl Med. 2023 Dec; 13(12): e1511. Published online 2023 Dec 13. doi: 10.1002/ctm2.1511

PMCID:: PMC10719540

Abstract Article PDF–14M

Select item 1040353114.

Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1

Jun-qi Luo, Tao-wei Yang, Jun Wu, Hou-hua Lai, Li-bin Zou, Wen-bin Chen, Xu-min Zhou, Dao-jun Lv, Sheng-ren Cen, Zi-ning Long, Yi-you Mao, Peng-xiang Zheng, Xiao-hong Su, Zhi-yong Xian, Fang-peng Shu, Xiang-ming Mao

Cell Death Dis. 2023 Aug; 14(8): 502. Published online 2023 Aug 4. doi: 10.1038/s41419-023-06007-4

PMCID:: PMC10403531

Abstract Article PDF–7.2M

Select item 1023661115.

MicroRNA‐324‐3p inhibits osteosarcoma progression by suppressing PGAM1‐mediated aerobic glycolysis

Yiping Weng, Weihao Duan, Xuecheng Yu, Furen Wu, Daibin Yang, Yuqing Jiang, Jingbin Wu, Muyi Wang, Xin Wang, Yifei Shen, Yunkun Zhang, Hua Xu

Cancer Sci. 2023 Jun; 114(6): 2345–2359. Published online 2023 Mar 21. doi: 10.1111/cas.15779

PMCID:: PMC10236611

Abstract Article PDF–13M

Select item 934859316.

PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway

Min Liu, Runmei Li, Min Wang, Ting Liu, Qiuru Zhou, Dong Zhang, Jian Wang, Meng Shen, Xiubao Ren, Qian Sun

Mol Oncol. 2022 Aug; 16(15): 2843–2860. Published online 2022 Jun 27. doi: 10.1002/1878-0261.13259

PMCID:: PMC9348593

Abstract Article PDF–18M

Select item 745302617.

PGAM1, regulated by miR-3614-5p, functions as an oncogene by activating transforming growth factor-β (TGF-β) signaling in the progression of non-small cell lung carcinoma

Fangfang Li, Hao Yang, Tiandong Kong, Shanshan Chen, Ping Li, Lu Chen, Jiuling Cheng, Guangying Cui, Guojun Zhang

Cell Death Dis. 2020 Aug; 11(8): 710. Published online 2020 Aug 27. doi: 10.1038/s41419-020-02900-4

PMCID:: PMC7453026

Abstract Article PDF–4.4M

Select item 738247518.

T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses

Koji Toriyama, Makoto Kuwahara, Hiroshi Kondoh, Takumi Mikawa, Nobuaki Takemori, Amane Konishi, Toshihiro Yorozuya, Takeshi Yamada, Tomoyoshi Soga, Atsushi Shiraishi, Masakatsu Yamashita

Commun Biol. 2020; 3: 394. Published online 2020 Jul 24. doi: 10.1038/s42003-020-01122-w

PMCID:: PMC7382475

Abstract Article PDF–2.3M

Select item 598875919.

Phosphoglyceric acid mutase-1 contributes to oncogenic mTOR-mediated tumor growth and confers non-small cell lung cancer patients with poor prognosis

Qian Sun, Shuzhan Li, Yanan Wang, Haiyong Peng, Xiying Zhang, Yu Zheng, Chunjia Li, Li Li, Rongrong Chen, Xinxin Chen, Wenjing Bai, Xiangli Jiang, Liang Liu, Feng Wei, Boshi Wang, Yu Zhang, Hui Li, Xiubao Ren, Hongbing Zhang

Cell Death Differ. 2018 Jun; 25(6): 1160–1173. Published online 2018 Jan 23. doi: 10.1038/s41418-017-0034-y

PMCID:: PMC5988759

Abstract Article PDF–2.8M

Select item 328171520.

Regulation of Glycolytic Enzyme Phosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation

William C. Hallows, Wei Yu, John M. Denu

J Biol Chem. 2012 Feb 3; 287(6): 3850–3858. Published online 2011 Dec 7. doi: 10.1074/jbc.M111.317404

PMCID:: PMC3281715

Abstract Article PDF–1.9M

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