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Select item 106904701.

Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages

Line Lykke Andersen, Yiqi Huang, Christian Urban, Lila Oubraham, Elena Winheim, Che Stafford, Dennis Nagl, Fionan O'Duill, Thomas Ebert, Thomas Engleitner, Søren Riis Paludan, Anne Krug, Roland Rad, Veit Hornung, Andreas Pichlmair

EMBO J. 2023 Dec; 42(23): e113279. Published online 2023 Oct 26. doi: 10.15252/embj.2022113279

PMCID:: PMC10690470

Article PDF–2.0M

Select item 100736262.

P2Y₁₁/IL-1 receptor crosstalk controls macrophage inflammation: a novel target for anti-inflammatory strategies?

Dominik Klaver, Martin Thurnher

Purinergic Signal. 2023 Sep; 19(3): 501–511. Published online 2023 Apr 5. doi: 10.1007/s11302-023-09932-3

PMCID:: PMC10073626

Article PDF–929K

Select item 94764233.

The P2Y₁₁ receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses

Dominik Klaver, Hubert Gander, Gabriele Dobler, Andrea Rahm, Martin Thurnher

Cell Mol Life Sci. 2022; 79(10): 519. Published online 2022 Sep 15. doi: 10.1007/s00018-022-04548-z

PMCID:: PMC9476423

Article PDF–2.3M

Select item 88267734.

The purinergic receptor P2Y11 choreographs the polarization, mitochondrial metabolism, and migration of T lymphocytes

Carola Ledderose, Sophie Bromberger, Christian J. Slubowski, Koichiro Sueyoshi, Dilan Aytan, Yong Shen, Wolfgang G. Junger

Sci Signal. Author manuscript; available in PMC 2022 Feb 9.

Published in final edited form as: Sci Signal. 2020 Sep 29; 13(651): eaba3300. Published online 2020 Sep 29. doi: 10.1126/scisignal.aba3300

PMCID:: PMC8826773

Article PDF–1.3M

Select item 87722875.

P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse

Carola Ledderose, Sophie Bromberger, Christian J. Slubowski, Koichiro Sueyoshi, Wolfgang G. Junger

J Leukoc Biol. Author manuscript; available in PMC 2022 Jan 20.

Published in final edited form as: J Leukoc Biol. 2021 Mar; 109(3): 497–508. Published online 2020 Jun 12. doi: 10.1002/JLB.2HI0520-191R

PMCID:: PMC8772287

Article PDF–2.1M

Select item 83613456.

High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y₁₁ protein levels in narcolepsy type 1

Rannveig Viste, Marte K Viken, Benedicte A Lie, Hilde T Juvodden, Sebjørg E H Nordstrand, Per M Thorsby, Terje Rootwelt, Birgitte R Kornum, Stine Knudsen-Heier

Sleep. 2021 Aug; 44(8): zsab062. Published online 2021 Mar 12. doi: 10.1093/sleep/zsab062

PMCID:: PMC8361345

Article PDF–4.2M

Select item 66955577.

The Human G Protein-Coupled ATP Receptor P2Y₁₁ Is Associated With IL-10 Driven Macrophage Differentiation

Georg Gruenbacher, Hubert Gander, Andrea Rahm, Gabriele Dobler, Astrid Drasche, Jakob Troppmair, Walter Nussbaumer, Martin Thurnher

Front Immunol. 2019; 10: 1870. Published online 2019 Aug 9. doi: 10.3389/fimmu.2019.01870

PMCID:: PMC6695557

Article PDF–3.0M

Select item 64841208.

Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors

Koichiro Sueyoshi, Carola Ledderose, Yong Shen, Albert H. Lee, Nathan I. Shapiro, Wolfgang G. Junger

J Biol Chem. 2019 Apr 19; 294(16): 6283–6293. Published online 2019 Feb 20. doi: 10.1074/jbc.RA118.007188

PMCID:: PMC6484120

Article PDF–2.0M

Select item 55149089.

Carcinoma-specific expression of P2Y₁₁ receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells

Madiha Khalid, Lucie Brisson, Menahil Tariq, Yunjie Hao, Roseline Guibon, Gaëlle Fromont, Sharifah Alawieyah Syed Mortadza, Fatema Mousawi, Sobia Manzoor, Sébastien Roger, Lin-Hua Jiang

Oncotarget. 2017 Jun 6; 8(23): 37278–37290. Published online 2017 Mar 14. doi: 10.18632/oncotarget.16191

PMCID:: PMC5514908

Article PDF–4.2M

Select item 361844410.

Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor

Hayato Sakaki, Mitsutoshi Tsukimoto, Hitoshi Harada, Yoshinori Moriyama, Shuji Kojima

PLoS One. 2013; 8(4): e59778. Published online 2013 Apr 5. doi: 10.1371/journal.pone.0059778

PMCID:: PMC3618444

Article PDF–1.6M

Select item 301928611.

Common variants in P2RY11 are associated with narcolepsy

Birgitte R Kornum, Minae Kawashima, Juliette Faraco, Ling Lin, Tom Rico, Stephanie Hesselson, Robert C Axtell, Hedwich Kuipers, Karin Weiner, Alexandra Hamacher, Matthias U Kassack, Fang Han, Stine Knudsen, Jing Li, Xiaosong Dong, Juliane Winkelmann, Giuseppe Plazzi, Sona Nevsimalova, Seung-Chul Hong, Yutaka Honda, Makoto Honda, Birgit Hogl, Thanh G N Ton, Jacques Montplaisir, Patrice Bourgin, David Kemlink, Yu-Shu Huang, Simon Warby, Mali Einen, Jasmin L Eshragh, Taku Miyagawa, Alex Desautels, Elisabeth Ruppert, Per Egil Hesla, Francesca Poli, Fabio Pizza, Birgit Frauscher, Jong-Hyun Jeong, Sung-Pil Lee, Kingman P Strohl, William T Longstreth, Jr, Mark Kvale, Marie Dobrovolna, Maurice M Ohayon, Gerald T Nepom, H-Erich Wichmann, Guy A Rouleau, Christian Gieger, Douglas F Levinson, Pablo V Gejman, Thomas Meitinger, Paul Peppard, Terry Young, Poul Jennum, Lawrence Steinman, Katsushi Tokunaga, Pui-Yan Kwok, Neil Risch, Joachim Hallmayer, Emmanuel Mignot

Nat Genet. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Nat Genet. 2011 Jan; 43(1): 66–71. Published online 2010 Dec 19. doi: 10.1038/ng.734

Correction in:: volume 43 on page 1040

PMCID:: PMC3019286

Article PDF–1.8M

Select item 229224512.

Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y₁₁ receptor

Kathryn R. Vaughan, Leanne Stokes, Lynne R. Prince, Sabine Meis, Matthias U. Kassack, Colin D. Bingle, Ian Sabroe, Annmarie Surprenant, Moira K.B. Whyte

J Immunol. Author manuscript; available in PMC 2008 Jun 15.

Published in final edited form as: J Immunol. 2007 Dec 15; 179(12): 8544–8553. doi: 10.4049/jimmunol.179.12.8544

PMCID:: PMC2292245

Article PDF–1.4M

Select item 190452113.

Structure and ligand-binding site characteristics of the human P2Y₁₁ nucleotide receptor deduced from computational modelling and mutational analysis

Jacques Zylberg, Denise Ecke, Bilha Fischer, Georg Reiser

Biochem J. 2007 Jul 15; 405(Pt 2): 277–286. Prepublished online 2007 Mar 6. Published online 2007 Jun 27. doi: 10.1042/BJ20061728

PMCID:: PMC1904521

Article PDF–729K

Select item 600248414.

Human P2Y₁₁ Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

Karin Dreisig, Louise Sund, Maja Wallentin Dommer, Nikolaj Pagh Kristensen, Kim Boddum, Rannveig Viste, Simon Fredholm, Niels Odum, Marja Jäättelä, Søren Skov, Birgitte R. Kornum

Front Immunol. 2018; 9: 1159. Published online 2018 Jun 8. doi: 10.3389/fimmu.2018.01159

PMCID:: PMC6002484

Article PDF–2.1M

Select item 500933715.

Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling

D. Avanzato, T. Genova, A. Fiorio Pla, M. Bernardini, S. Bianco, B. Bussolati, D. Mancardi, E. Giraudo, F. Maione, P. Cassoni, I. Castellano, L. Munaron

Sci Rep. 2016; 6: 32602. Published online 2016 Sep 2. doi: 10.1038/srep32602

Correction in:: Sci Rep. 2016; 6: 35897.

PMCID:: PMC5009337

Article PDF–2.0M

Select item 1093320116.

Crosstalk between purinergic receptor P2Y₁₁ and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages

Dominik Klaver, Hubert Gander, Beatrice Frena, Marco Amato, Martin Thurnher

Cell Mol Life Sci. 2024; 81(1): 132. Published online 2024 Mar 13. doi: 10.1007/s00018-024-05158-7

PMCID:: PMC10933201

Article PDF–4.5M

Select item 335059417.

Purinergic receptors expressed in human skeletal muscle fibres

A. Bornø, T. Ploug, L. T. Bune, J. B. Rosenmeier, P. Thaning

Purinergic Signal. 2012 Jun; 8(2): 255–264. Published online 2011 Nov 4. doi: 10.1007/s11302-011-9279-y

PMCID:: PMC3350594

Article PDF–419K

Select item 328827918.

TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy

Fang Han, Ling Lin, Jing Li, Adi Aran, Song X. Dong, Pei. An, Long Zhao, Qian Y. Li, Han Yan, Jie S. Wang, Hui Y. Gao, Mei Li, Zhan C. Gao, Kingman P. Strohl, Emmanuel Mignot

Sleep Med. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Sleep Med. 2012 Mar; 13(3): 269–272. Published online 2011 Dec 15. doi: 10.1016/j.sleep.2011.06.020

PMCID:: PMC3288279

Article PDF–320K

Select item 381431119.

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Fang Han, Juliette Faraco, Xiao Song Dong, Hanna M. Ollila, Ling Lin, Jing Li, Pei An, Shan Wang, Ke Wei Jiang, Zhan Cheng Gao, Long Zhao, Han Yan, Ya Nan Liu, Qing Hua Li, Xiao Zhe Zhang, Yan Hu, Jing Yu Wang, Yun Hui Lu, Chang Jun Lu, Wei Zhou, Joachim Hallmayer, Yu Shu Huang, Kingman P. Strohl, Thomas Pollmächer, Emmanuel Mignot

PLoS Genet. 2013 Oct; 9(10): e1003880. Published online 2013 Oct 31. doi: 10.1371/journal.pgen.1003880

PMCID:: PMC3814311

Article PDF–580K

Select item 646186420.

LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition

Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang

Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3

PMCID:: PMC6461864

Article PDF–11M

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