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Select item 109525801.

Exploring bias in platelet P2Y₁ signalling: Host defence versus haemostasis

Dingxin Pan, Graham Ladds, Khondaker Miraz Rahman, Simon C. Pitchford

Br J Pharmacol. 2024 Feb; 181(4): 580–592. Published online 2023 Aug 2. doi: 10.1111/bph.16191

PMCID:: PMC10952580

Article PDF–1.6M

Select item 107927532.

Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics

Arnaud Dance, Justine Fernandes, Bénédicte Toussaint, Emmanuel Vaillant, Raphaël Boutry, Morgane Baron, Hélène Loiselle, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Mark Ibberson, Michel Marre, Marie Gernay, Marjorie Fadeur, Nicolas Paquot, Martine Vaxillaire, Mathilde Boissel, Souhila Amanzougarene, Mehdi Derhourhi, Amna Khamis, Philippe Froguel, Amélie Bonnefond

Mol Metab. 2024 Jan; 79: 101867. Published online 2023 Dec 28. doi: 10.1016/j.molmet.2023.101867

PMCID:: PMC10792753

Article PDF–1.6M

Select item 66355413.

Autocrine stimulation of P2Y1 receptors is part of the purinergic signaling mechanism that regulates T cell activation

Tobias Woehrle, Carola Ledderose, Jessica Rink, Christian Slubowski, Wolfgang G. Junger

Purinergic Signal. 2019 Jun; 15(2): 127–137. Published online 2019 Mar 27. doi: 10.1007/s11302-019-09653-6

PMCID:: PMC6635541

Article PDF–2.1M

Select item 40091504.

P2Y Receptor Modulation of ATP Release in the Urothelium

Kylie J. Mansfield, Jessica R. Hughes

Biomed Res Int. 2014; 2014: 830374. Published online 2014 Apr 14. doi: 10.1155/2014/830374

PMCID:: PMC4009150

Article PDF–762K

Select item 37386305.

NCI-H295R, a Human Adrenal Cortex-Derived Cell Line, Expresses Purinergic Receptors Linked to Ca²⁺-Mobilization/Influx and Cortisol Secretion

Haruhisa Nishi, Hirokazu Arai, Toshihiko Momiyama

PLoS One. 2013; 8(8): e71022. Published online 2013 Aug 8. doi: 10.1371/journal.pone.0071022

PMCID:: PMC3738630

Article PDF–7.2M

Select item 31407126.

ACTIVATION OF THE P2Y₁ RECEPTOR INDUCES APOPTOSIS AND INHIBITS PROLIFERATION OF PROSTATE CANCER CELLS

Qiang Wei, Stefano Costanzi, Qiu-Zhen Liu, Zhan-Guo Gao, Kenneth A. Jacobson

Biochem Pharmacol. Author manuscript; available in PMC 2012 Aug 15.

Published in final edited form as: Biochem Pharmacol. 2011 Aug 15; 82(4): 418–425. Published online 2011 May 23. doi: 10.1016/j.bcp.2011.05.013

PMCID:: PMC3140712

Article PDF–2.1M

Select item 28808887.

Structure Activity Relationship of (N)-Methanocarba Phosphonate Analogues of 5’-AMP as Cardioprotective Agents Acting Through a Cardiac P2X Receptor

T. Santhosh Kumar, Si-Yuan Zhou, Bhalchandra V. Joshi, Ramachandran Balasubramanian, Tiehong Yang, Bruce T. Liang, Kenneth A. Jacobson

J Med Chem. Author manuscript; available in PMC 2011 Mar 25.

Published in final edited form as: J Med Chem. 2010 Mar 25; 53(6): 2562–2576. doi: 10.1021/jm9018542

PMCID:: PMC2880888

Article PDF–2.4M

Select item 15725848.

Two subtypes of G protein-coupled nucleotide receptors, P2Y₁ and P2Y₂ are involved in calcium signalling in glioma C6 cells

Paweł Sabała, Rafał Czajkowski, Krzysztof Przybyłek, Katarzyna Kalita, Leszek Kaczmarek, Jolanta Barańska

Br J Pharmacol. 2001 Jan; 132(2): 393–402. doi: 10.1038/sj.bjp.0703843

PMCID:: PMC1572584

Article PDF–271K

Select item 15594539.

Calmodulin interacts with the platelet ADP receptor P2Y₁

Jane F. Arthur, Yang Shen, Fi-Tjen Mu, Catherine Leon, Christian Gachet, Michael C. Berndt, Robert K. Andrews

Biochem J. 2006 Sep 15; 398(Pt 3): 339–343. Prepublished online 2006 Jul 18. Published online 2006 Aug 29. doi: 10.1042/BJ20060822

PMCID:: PMC1559453

Article PDF–198K

Select item 986786210.

Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation

Chunyan Su, Zhishan Zhang, Jintu Chen, Mengcha Tian, Conglian Wu, Tao Zhang

BMC Cardiovasc Disord. 2023; 23: 41. Published online 2023 Jan 21. doi: 10.1186/s12872-023-03075-4

PMCID:: PMC9867862

Article PDF–767K

Select item 782719211.

Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy

Juan Carlos Gil-Redondo, Jagoba Iturri, Felipe Ortega, Raquel Pérez-Sen, Andreas Weber, María Teresa Miras-Portugal, José Luis Toca-Herrera, Esmerilda G. Delicado

Int J Mol Sci. 2021 Jan; 22(2): 624. Published online 2021 Jan 10. doi: 10.3390/ijms22020624

PMCID:: PMC7827192

Article PDF–3.3M

Select item 743275812.

Contribution of P2X4 Receptors to CNS Function and Pathophysiology

Alejandro Montilla, Gilda Paloma Mata, Carlos Matute, Maria Domercq

Int J Mol Sci. 2020 Aug; 21(15): 5562. Published online 2020 Aug 3. doi: 10.3390/ijms21155562

PMCID:: PMC7432758

Article PDF–624K

Select item 575128013.

Population-Specific Associations of Deleterious Rare Variants in Coding Region of P2RY1–P2RY12 Purinergic Receptor Genes in Large-Vessel Ischemic Stroke Patients

Piotr K. Janicki, Ceren Eyileten, Victor Ruiz-Velasco, Khaled Anwar Sedeek, Justyna Pordzik, Anna Czlonkowska, Iwona Kurkowska-Jastrzebska, Shigekazu Sugino, Yuka Imamura-Kawasawa, Dagmara Mirowska-Guzel, Marek Postula

Int J Mol Sci. 2017 Dec; 18(12): 2678. Published online 2017 Dec 11. doi: 10.3390/ijms18122678

PMCID:: PMC5751280

Article PDF–719K

Select item 535674314.

Pin1 induces the ADP-induced migration of human dental pulp cells through P2Y1 stabilization

Soo-A Kim, Hong Seok Choi, Sang-Gun Ahn

Oncotarget. 2016 Dec 20; 7(51): 85381–85392. Published online 2016 Nov 16. doi: 10.18632/oncotarget.13377

PMCID:: PMC5356743

Article PDF–6.0M

Select item 508294915.

P2Y₁ Receptor Signaling Contributes to High Salt-Induced Priming of the NLRP3 Inflammasome in Retinal Pigment Epithelial Cells

Philipp Prager, Margrit Hollborn, Anja Steffen, Peter Wiedemann, Leon Kohen, Andreas Bringmann

PLoS One. 2016; 11(10): e0165653. Published online 2016 Oct 27. doi: 10.1371/journal.pone.0165653

PMCID:: PMC5082949

Article PDF–4.7M

Select item 502362716.

Coupling switch of P2Y-IP₃ receptors mediates differential Ca²⁺ signaling in human embryonic stem cells and derived cardiovascular progenitor cells

Jijun Huang, Min Zhang, Peng Zhang, He Liang, Kunfu Ouyang, Huang-Tian Yang

Purinergic Signal. 2016 Sep; 12(3): 465–478. Published online 2016 Apr 20. doi: 10.1007/s11302-016-9512-9

PMCID:: PMC5023627

Article PDF–4.9M

Select item 490747617.

ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y₁ Purinergic Receptor via a YPX₃L Motif

Michael R. Dores, Neil J. Grimsey, Francisco Mendez, JoAnn Trejo

PLoS One. 2016; 11(6): e0157587. Published online 2016 Jun 14. doi: 10.1371/journal.pone.0157587

PMCID:: PMC4907476

Article PDF–3.4M

Select item 449754518.

Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors

Maurish Bukhari, Han Deng, Noelle Jones, Zachary Towne, Craig D. Woodworth, Damien S.K. Samways

FEBS Lett. Author manuscript; available in PMC 2016 Jun 4.

Published in final edited form as: FEBS Lett. 2015 Jun 4; 589(13): 1498–1504. Published online 2015 May 1. doi: 10.1016/j.febslet.2015.04.044

PMCID:: PMC4497545

Article PDF–846K

Select item 444139519.

P2Y₁₂ or P2Y₁ inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions

S. F. Maloney, Lawrence F. Brass, S. L. Diamond

Integr Biol (Camb) Author manuscript; available in PMC 2015 May 22.

Published in final edited form as: Integr Biol (Camb). 2010 Apr; 2(4): 183–192. Published online 2010 Jan 5. doi: 10.1039/b919728a

PMCID:: PMC4441395

Article PDF–1.2M

Select item 440892720.

Two disparate ligand binding sites in the human P2Y₁ receptor

Dandan Zhang, Zhan-Guo Gao, Kaihua Zhang, Evgeny Kiselev, Steven Crane, Jiang Wang, Silvia Paoletta, Cuiying Yi, Limin Ma, Wenru Zhang, Gye Won Han, Hong Liu, Vadim Cherezov, Vsevolod Katritch, Hualiang Jiang, Raymond C. Stevens, Kenneth A. Jacobson, Qiang Zhao, Beili Wu

Nature. Author manuscript; available in PMC 2016 Apr 16.

Published in final edited form as: Nature. 2015 Apr 16; 520(7547): 317–321. Published online 2015 Mar 30. doi: 10.1038/nature14287

PMCID:: PMC4408927

Article PDF–2.8M

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