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Items: 1 to 20 of 99

1.
An endoplasmic reticulum stress-related signature featuring ASNS for predicting prognosis and immune landscape in prostate cancer
Zhenyu Wu, Zhenquan Wu, Jie Zeng, Yaxuan Liu, Yue Wang, Huixin Li, Taolin Xia, Weitao Liu, Zhe Lin, Wenfeng Xu
Aging (Albany NY) 2024 Jan 15; 16(1): 43–65. Published online 2024 Jan 10. doi: 10.18632/aging.205280
PMCID:
PMC10817364
ArticlePDF–4.8M
2.
Asparagine synthetase regulates lung-cancer metastasis by stabilizing the β-catenin complex and modulating mitochondrial response
Dong-Jing Cai, Zi-Yu Zhang, Yue Bu, Li Li, Yue-Zhen Deng, Lun-Quan Sun, Cheng-Ping Hu, Min Li
Cell Death Dis. 2022 Jun; 13(6): 566. Published online 2022 Jun 23. doi: 10.1038/s41419-022-05015-0
PMCID:
PMC9226154
ArticlePDF–6.9M
3.
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL
Koshi Akahane, Shunsuke Kimura, Kunio Miyake, Atsushi Watanabe, Keiko Kagami, Kentaro Yoshimura, Tamao Shinohara, Daisuke Harama, Shin Kasai, Kumiko Goi, Tomoko Kawai, Kenichiro Hata, Nobutaka Kiyokawa, Katsuyoshi Koh, Toshihiko Imamura, Keizo Horibe, A. Thomas Look, Masayoshi Minegishi, Kanji Sugita, Junko Takita, Takeshi Inukai
Blood Adv. 2022 Jan 11; 6(1): 212–224. Published online 2022 Jan 10. doi: 10.1182/bloodadvances.2021004271
PMCID:
PMC8753197
ArticlePDF–1.4M
4.
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency
Chun Wang, Guiyuan He, Yusong Ge, Runjie Li, Zhenguo Li, Yongzhong Lin
Mol Genet Genomic Med. 2020 Jun; 8(6): e1235. Published online 2020 Apr 7. doi: 10.1002/mgg3.1235
PMCID:
PMC7284041
ArticlePDF–1.2M
5.
Report of four novel variants in ASNS causing asparagine synthetase deficiency and review of literature
Chelna Galada, Malavika Hebbar, Leslie Lewis, Santosh Soans, Rajagopal Kadavigere, Anshika Srivastava, Stephanie Bielas, Katta M Girisha, Anju Shukla
Congenit Anom (Kyoto) Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Congenit Anom (Kyoto). 2018 Sep; 58(5): 181–182. Published online 2018 Feb 20. doi: 10.1111/cga.12275
PMCID:
PMC6338226
ArticlePDF–188K
6.
Characterization of a Novel Variant in Siblings with Asparagine Synthetase Deficiency
Stephanie J. Sacharow, Elizabeth E. Dudenhausen, Carrie L. Lomelino, Lance Rodan, Christelle Moufawad El Achkar, Heather E. Olson, Casie A Genetti, Pankaj B. Agrawal, Robert McKenna, Michael S. Kilberg
Mol Genet Metab. Author manuscript; available in PMC 2019 Mar 1.
Published in final edited form as: Mol Genet Metab. 2018 Mar; 123(3): 317–325. Published online 2017 Dec 20. doi: 10.1016/j.ymgme.2017.12.433
PMCID:
PMC5832599
ArticlePDF–944K
7.
Asparagine synthetase: Function, structure, and role in disease
Carrie L. Lomelino, Jacob T. Andring, Robert McKenna, Michael S. Kilberg
J Biol Chem. 2017 Dec 8; 292(49): 19952–19958. Published online 2017 Oct 30. doi: 10.1074/jbc.R117.819060
PMCID:
PMC5723983
ArticlePDF–1.9M
8.
Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia
Mohsen Ben Tanfous, Bahram Sharif-Askari, Francesco Ceppi, Haithem Laaribi, Vincent Gagné, Julie Rousseau, Malgorzata Labuda, Lewis B. Silverman, Stephen E. Sallan, Donna Neuberg, Jeffery L. Kutok, Daniel Sinnett, Caroline Laverdière, Maja Krajinovic
Clin Cancer Res. Author manuscript; available in PMC 2015 Jul 15.
Published in final edited form as: Clin Cancer Res. 2015 Jan 15; 21(2): 329–334. Published online 2014 Jun 6. doi: 10.1158/1078-0432.CCR-14-0508
PMCID:
PMC4258187
ArticlePDF–605K
9.
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines
Philip L. Lorenzi, Jenny Llamas, Michele Gunsior, Laurent Ozbun, William C. Reinhold, Sudhir Varma, Helen Ji, Hijoo Kim, Amy A. Hutchinson, Elise C. Kohn, Paul K. Goldsmith, Michael J. Birrer, John N. Weinstein
Mol Cancer Ther. Author manuscript; available in PMC 2014 Aug 6.
Published in final edited form as: Mol Cancer Ther. 2008 Oct; 7(10): 3123–3128. doi: 10.1158/1535-7163.MCT-08-0589
PMCID:
PMC4123961
ArticlePDF–280K
10.
Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinoma
B Zhang, L-W Dong, Y-X Tan, J Zhang, Y-F Pan, C Yang, M-H Li, Z-W Ding, L-J Liu, T-Y Jiang, J-H Yang, H-Y Wang
Br J Cancer. 2013 Jul 9; 109(1): 14–23. Published online 2013 Jun 13. doi: 10.1038/bjc.2013.293
PMCID:
PMC3708586
ArticlePDF–2.4M
11.
Asparagine synthetase: regulation by cell stress and involvement in tumor biology
Mukundh N. Balasubramanian, Elizabeth A. Butterworth, Michael S. Kilberg
Am J Physiol Endocrinol Metab. 2013 Apr 15; 304(8): E789–E799. Published online 2013 Feb 12. doi: 10.1152/ajpendo.00015.2013
PMCID:
PMC3625782
Article
12.
Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells
Tadayuki Akagi, Dong Yin, Norihiko Kawamata, Claus R. Bartram, Wolf-K. Hofmann, Jee Hoon Song, Carl W. Miller, Monique L. den Boer, H. Phillip Koeffler
Leuk Res. Author manuscript; available in PMC 2010 Jul 1.
Published in final edited form as: Leuk Res. 2009 Jul; 33(7): 991–996. Published online 2008 Dec 2. doi: 10.1016/j.leukres.2008.10.022
PMCID:
PMC2731768
ArticlePDF–492K
13.
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase
Shotaro Iwamoto, Keichiro Mihara, James R. Downing, Ching-Hon Pui, Dario Campana
J Clin Invest. 2007 Apr 2; 117(4): 1049–1057. Published online 2007 Mar 22. doi: 10.1172/JCI30235
PMCID:
PMC1821067
ArticlePDF–973K
14.
Molecular cloning of a gene that is necessary for G1 progression in mammalian cells.
A Greco, M Ittmann, C Basilico
Proc Natl Acad Sci U S A. 1987 Mar; 84(6): 1565–1569. doi: 10.1073/pnas.84.6.1565
PMCID:
PMC304476
SummaryPage BrowsePDF–1.2M
15.
Integrated Bioinformatics Analysis Identified ASNS and DDIT3 as the Therapeutic Target in Castrate-Resistant Prostate Cancer
Ae Ryang Jung, Sun Shin, Mee Young Kim, U-Syn Ha, Sung-Hoo Hong, Ji Youl Lee, Sae Woong Kim, Yeun-Jun Chung, Yong Hyun Park
Int J Mol Sci. 2024 Mar; 25(5): 2836. Published online 2024 Feb 29. doi: 10.3390/ijms25052836
PMCID:
PMC10932076
ArticlePDF–24M
16.
Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL
Atsushi Watanabe, Kunio Miyake, Jessica Nordlund, Ann-Christine Syvänen, Louise van der Weyden, Hiroaki Honda, Norimasa Yamasaki, Akiko Nagamachi, Toshiya Inaba, Tomokatsu Ikawa, Kevin Y. Urayama, Nobutaka Kiyokawa, Akira Ohara, Shunsuke Kimura, Yasuo Kubota, Junko Takita, Hiroaki Goto, Kimiyoshi Sakaguchi, Masayoshi Minegishi, Shotaro Iwamoto, Tamao Shinohara, Keiko Kagami, Masako Abe, Koshi Akahane, Kumiko Goi, Kanji Sugita, Takeshi Inukai
Blood. 2020 Nov 12; 136(20): 2319–2333. Prepublished online 2020 Jun 23. doi: 10.1182/blood.2019004090
PMCID:
PMC7702480
Article
17.
Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response
Akito Nakamura, Tadahiro Nambu, Shunsuke Ebara, Yuka Hasegawa, Kosei Toyoshima, Yasuko Tsuchiya, Daisuke Tomita, Jun Fujimoto, Osamu Kurasawa, Chisato Takahara, Ayumi Ando, Ryuichi Nishigaki, Yoshinori Satomi, Akito Hata, Takahito Hara
Proc Natl Acad Sci U S A. 2018 Aug 14; 115(33): E7776–E7785. Published online 2018 Jul 30. doi: 10.1073/pnas.1805523115
PMCID:
PMC6099884
ArticlePDF–2.1M
18.
Polymorphism in asparagine synthetase is associated with overall survival of hepatocellular carcinoma patients
Wei Li, Chengwei Dong
BMC Gastroenterol. 2017; 17: 79. Published online 2017 Jun 19. doi: 10.1186/s12876-017-0635-4
PMCID:
PMC5477286
ArticlePDF–803K
19.
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy
Elizabeth K. Ruzzo, José-Mario Capo-Chichi, Bruria Ben-Zeev, David Chitayat, Hanqian Mao, Andrea L. Pappas, Yuki Hitomi, Yi-Fan Lu, Xiaodi Yao, Fadi F. Hamdan, Kimberly Pelak, Haike Reznik-Wolf, Ifat Bar-Joseph, Danit Oz-Levi, Dorit Lev, Tally Lerman-Sagie, Esther Leshinsky-Silver, Yair Anikster, Edna Ben-Asher, Tsviya Olender, Laurence Colleaux, Jean-Claude Décarie, Susan Blaser, Brenda Banwell, Rasesh B. Joshi, Xiao-Ping He, Lysanne Patry, Rachel J. Silver, Sylvia Dobrzeniecka, Mohammad S. Islam, Abul Hasnat, Mark E. Samuels, Dipendra K. Aryal, Ramona M. Rodriguiz, Yong-hui Jiang, William C. Wetsel, James O. McNamara, Guy A. Rouleau, Debra L. Silver, Doron Lancet, Elon Pras, Grant A. Mitchell, Jacques L. Michaud, David B. Goldstein
Neuron. Author manuscript; available in PMC 2014 Oct 16.
Published in final edited form as: Neuron. 2013 Oct 16; 80(2): 10.1016/j.neuron.2013.08.013. doi: 10.1016/j.neuron.2013.08.013
PMCID:
PMC3820368
ArticlePDF–1.7M
20.
Over-expression of asparagine synthetase and matrix metalloproteinase 19 confers cisplatin sensitivity in nasopharyngeal carcinoma cells
Ran-Yi Liu, Zizheng Dong, Jianguo Liu, Ling Zhou, Wenlin Huang, Sok Kean Khoo, Zhongfa Zhang, David Petillo, Bin Tean Teh, Chao-Nan Qian, Jian-Ting Zhang
Mol Cancer Ther. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Mol Cancer Ther. 2013 Oct; 12(10): 2157–2166. Published online 2013 Aug 16. doi: 10.1158/1535-7163.MCT-12-1190
PMCID:
PMC3795908
ArticlePDF–3.1M

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