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Select item 79629091.

MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis

Christopher C Y Mak, Dan Doherty, Angela E Lin, Nancy Vegas, Megan T Cho, Géraldine Viot, Clémantine Dimartino, James D Weisfeld-Adams, Davor Lessel, Shelagh Joss, Chumei Li, Claudia Gonzaga-Jauregui, Yuri A Zarate, Nadja Ehmke, Denise Horn, Caitlin Troyer, Sarina G Kant, Youngha Lee, Gisele E Ishak, Gordon Leung, Amanda Barone Pritchard, Sandra Yang, Eric G Bend, Francesca Filippini, Chelsea Roadhouse, Nicolas Lebrun, Michele G Mehaffey, Pierre-Marie Martin, Benjamin Apple, Francisca Millan, Oliver Puk, Mariette J V Hoffer, Lindsay B Henderson, Ruth McGowan, Ingrid M Wentzensen, Steven Pei, Farah R Zahir, Mullin Yu, William T Gibson, Ann Seman, Marcie Steeves, Jill R Murrell, Sabine Luettgen, Elizabeth Francisco, Tim M Strom, Louise Amlie-Wolf, Angela M Kaindl, William G Wilson, Sara Halbach, Lina Basel-Salmon, Noa Lev-El, Jonas Denecke, Lisenka E L M Vissers, Kelly Radtke, Jamel Chelly, Elaine Zackai, Jan M Friedman, Michael J Bamshad, Deborah A Nickerson, University of Washington Center for Mendelian Genomics, Russell R Reid, Koenraad Devriendt, Jong-Hee Chae, Elliot Stolerman, Carey McDougall, Zöe Powis, Thierry Bienvenu, Tiong Y Tan, Naama Orenstein, William B Dobyns, Joseph T Shieh, Murim Choi, Darrel Waggoner, Karen W Gripp, Michael J Parker, Joan Stoler, Stanislas Lyonnet, Valérie Cormier-Daire, David Viskochil, Trevor L Hoffman, Jeanne Amiel, Brian H Y Chung, Christopher T Gordon

Brain. 2020 Jan; 143(1): 55–68. Published online 2019 Dec 13. doi: 10.1093/brain/awz379

Correction in:: Brain. 2020 Mar; 143(3): e24.

PMCID:: PMC7962909

Article PDF–1.7M

Select item 77882952.

MN1 overexpression with varying tumor grade is a promising predictor of survival of glioma patients

Masum Saini, Ajaya Nand Jha, Rajiv Tangri, Md Qudratullah, Sher Ali

Hum Mol Genet. 2020 Nov 1; 29(21): 3532–3545. Published online 2020 Oct 26. doi: 10.1093/hmg/ddaa231

PMCID:: PMC7788295

Article PDF–1.6M

Select item 64194703.

Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis

Norman L. Lehman, Aisulu Usubalieva, Tong Lin, Sariah J. Allen, Quynh T. Tran, Bret C. Mobley, Roger E. McLendon, Matthew J. Schniederjan, Maria-Magdalena Georgescu, Marta Couce, Mohanpal S. Dulai, Jack M. Raisanen, Mousa Al Abbadi, Cheryl A. Palmer, Eyas M. Hattab, Brent A. Orr

Acta Neuropathol Commun. 2019; 7: 42. Published online 2019 Mar 15. doi: 10.1186/s40478-019-0689-3

PMCID:: PMC6419470

Article PDF–2.4M

Select item 53420374.

Variable but consistent pattern of Meningioma 1 gene (MN1) expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection

Sonia Carturan, Jessica Petiti, Valentina Rosso, Chiara Calabrese, Elisabetta Signorino, Giada Bot-Sartor, Paolo Nicoli, Daniela Gallo, Enrico Bracco, Alessandro Morotti, Cristina Panuzzo, Enrico Gottardi, Francesco Frassoni, Giuseppe Saglio, Daniela Cilloni

Oncotarget. 2016 Nov 8; 7(45): 74082–74096. Published online 2016 Sep 27. doi: 10.18632/oncotarget.12269

PMCID:: PMC5342037

Article PDF–2.5M

Select item 51542485.

High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells

Masashi Numata, Mehmet Deniz Yener, Sema Sırma Ekmekçi, Müge Aydın, Gerard Grosveld, Monica Cardone, Sabrina Terranova, Ramon Klein Geltink, Uğur Özbek, Emrah Özçelik, Çağrı Güleç, Sema Anak, Serap Karaman, Gülyüz Öztürk, Meral Akbıyık, Ayten Kandilci

Leuk Res. Author manuscript; available in PMC 2016 Dec 13.

Published in final edited form as: Leuk Res. 2015 Aug; 39(8): 906–912. Published online 2015 Jun 12. doi: 10.1016/j.leukres.2015.05.013

PMCID:: PMC5154248

Article PDF–1.4M

Select item 47952386.

Chromosome 22q12.1 microdeletions: confirmation of the MN1 gene as a candidate gene for cleft palate

Jeroen Breckpot, Britt-Marie Anderlid, Yasemin Alanay, Moira Blyth, Afane Brahimi, Bénédicte Duban-Bedu, Odile Gozé, Helen Firth, Mustafa Cengiz Yakicier, Greet Hens, Maissa Rayyan, Eric Legius, Joris Robert Vermeesch, Koen Devriendt

Eur J Hum Genet. 2016 Jan; 24(1): 51–58. Published online 2015 May 6. doi: 10.1038/ejhg.2015.65

PMCID:: PMC4795238

Article PDF–872K

Select item 42569117.

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Suzan Imren, Michael Heuser, Maura Gasparetto, Philip A. Beer, Gudmundur L. Norddahl, Ping Xiang, Ling Chen, Tobias Berg, Garrett W. Rhyasen, Patricia Rosten, Gyeongsin Park, Yeonsook Moon, Andrew P. Weng, Connie J. Eaves, R. Keith Humphries

Blood. 2014 Dec 4; 124(24): 3608–3612. Prepublished online 2014 Oct 22. doi: 10.1182/blood-2014-04-564666

PMCID:: PMC4256911

Article

Select item 32914908.

Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia

Sebastian Schwind, Guido Marcucci, Jessica Kohlschmidt, Michael D. Radmacher, Krzysztof Mrózek, Kati Maharry, Heiko Becker, Klaus H. Metzeler, Susan P. Whitman, Yue-Zhong Wu, Bayard L. Powell, Maria R. Baer, Jonathan E. Kolitz, Andrew J. Carroll, Richard A. Larson, Michael A. Caligiuri, Clara D. Bloomfield

Blood. 2011 Oct 13; 118(15): 4188–4198. Prepublished online 2011 Aug 9. doi: 10.1182/blood-2011-06-357764

PMCID:: PMC3291490

Article

Select item 32023069.

MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression

Magda A. Meester-Smoor, Marjolein J.F.W. Janssen, Gerard C. Grosveld, Annelies de Klein, Wilfred F.J. van IJcken, Hannie Douben, Ellen C. Zwarthoff

Carcinogenesis. 2008 Oct; 29(10): 2025–2034. Published online 2008 Jul 16. doi: 10.1093/carcin/bgn168

PMCID:: PMC3202306

Article PDF–1.7M

Select item 271694110.

Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

Christian Langer, Guido Marcucci, Kelsi B. Holland, Michael D. Radmacher, Kati Maharry, Peter Paschka, Susan P. Whitman, Krzysztof Mrózek, Claudia D. Baldus, Ravi Vij, Bayard L. Powell, Andrew J. Carroll, Jonathan E. Kolitz, Michael A. Caligiuri, Richard A. Larson, Clara D. Bloomfield

J Clin Oncol. 2009 Jul 1; 27(19): 3198–3204. Published online 2009 May 18. doi: 10.1200/JCO.2008.20.6110

PMCID:: PMC2716941

Article PDF–1.6M

Select item 238727411.

MN1, a novel player in human AML

Gerard C. Grosveld

Blood Cells Mol Dis. Author manuscript; available in PMC 2008 May 20.

Published in final edited form as: Blood Cells Mol Dis. 2007; 39(3): 336–339. Published online 2007 Aug 14. doi: 10.1016/j.bcmd.2007.06.009

PMCID:: PMC2387274

Article PDF–273K

Select item 999203412.

Early ependymal tumor with MN1-BEND2 fusion: a mostly cerebral tumor of female children with a good prognosis that is distinct from classical astroblastoma

Norman L. Lehman

J Neurooncol. 2023; 161(3): 425–439. Published online 2023 Jan 6. doi: 10.1007/s11060-022-04222-1

PMCID:: PMC9992034

Article PDF–2.0M

Select item 927235813.

METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma

Hong-Bo Li, Gang Huang, Jian Tu, Dong-Ming Lv, Qing-Lin Jin, Jun-Kai Chen, Yu-Tong Zou, Dung-Fang Lee, Jing-Nan Shen, Xian-Biao Xie

eBioMedicine. 2022 Aug; 82: 104142. Published online 2022 Jul 7. doi: 10.1016/j.ebiom.2022.104142

PMCID:: PMC9272358

Article PDF–6.5M

Select item 748116614.

Allogeneic stem cell transplantation mitigates the adverse prognostic impact of high diagnostic BAALC and MN1 expression in AML

Madlen Jentzsch, Marius Bill, Juliane Grimm, Dominic Brauer, Donata Backhaus, Karoline Goldmann, Julia Schulz, Dietger Niederwieser, Uwe Platzbecker, Sebastian Schwind

Ann Hematol. 2020; 99(10): 2417–2427. Published online 2020 Aug 29. doi: 10.1007/s00277-020-04235-8

PMCID:: PMC7481166

Article PDF–1.0M

Select item 719350015.

Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia

Amit Sharma, Nidhi Jyotsana, Razif Gabdoulline, Dirk Heckl, Florian Kuchenbauer, Robert K. Slany, Arnold Ganser, Michael Heuser

Haematologica. 2020 May; 105(5): 1294–1305. Prepublished online 2019 Aug 14. doi: 10.3324/haematol.2018.211201

PMCID:: PMC7193500

Article PDF–2.4M

Select item 472049916.

Exome Sequencing on Malignant Meningiomas Identified Mutations in Neurofibromatosis Type 2 (NF2) and Meningioma 1 (MN1) Genes

Xu Zhang, Haiying Jia, Yao Lu, Chengliang Dong, Jinghui Hou, Zheng Wang, Feng Wang, Hongbin Zhong, Lin Wang, Kai Wang

Discov Med. Author manuscript; available in PMC 2016 Jan 20.

Published in final edited form as: Discov Med. 2014 Dec; 18(101): 301–311.

PMCID:: PMC4720499

Article PDF–524K

Select item 273163917.

Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation

Ayten Kandilci, Gerard C. Grosveld

Blood. 2009 Aug 20; 114(8): 1596–1606. Prepublished online 2009 Jun 26. doi: 10.1182/blood-2009-02-205443

PMCID:: PMC2731639

Article

Select item 189524118.

MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice

Hiroyuki Kawagoe, Gerard C. Grosveld

Blood. 2005 Dec 15; 106(13): 4278–4286. Prepublished online 2005 Aug 4. doi: 10.1182/blood-2005-04-1674

PMCID:: PMC1895241

Article

Select item 838005619.

Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML.

Simone S. Riedel, Congcong Lu, Hongbo M. Xie, Kevin Nestler, Marit W. Vermunt, Alexandra Lenard, Laura Bennett, Nancy A. Speck, Ichiro Hanamura, Julie Lessard, Gerd A. Blobel, Benjamin A. Garcia, Kathrin M. Bernt

Mol Cell. Author manuscript; available in PMC 2022 Jun 3.

Published in final edited form as: Mol Cell. 2021 Jun 3; 81(11): 2332–2348.e9. Published online 2021 May 10. doi: 10.1016/j.molcel.2021.04.014

PMCID:: PMC8380056

Article PDF–3.4M

Select item 341921320.

Overexpression of MN1 Confers Resistance to Chemotherapy, Accelerates Leukemia Onset, and Suppresses p53 and Bim Induction

Timothy S. Pardee

PLoS One. 2012; 7(8): e43185. Published online 2012 Aug 14. doi: 10.1371/journal.pone.0043185

PMCID:: PMC3419213

Article PDF–1.1M

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