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Select item 70040811.

A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD‐Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis

Celia L Gregson, Dylan J. M. Bergen, Paul Leo, Richard B Sessions, Lawrie Wheeler, April Hartley, Scott Youlten, Peter I Croucher, Aideen M McInerney‐Leo, William Fraser, Jonathan CY Tang, Lisa Anderson, Mhairi Marshall, Leon Sergot, Lavinia Paternoster, George Davey Smith, The AOGC Consortium, Matthew A Brown, Chrissy Hammond, John P Kemp, Jon H Tobias, Emma L Duncan

J Bone Miner Res. 2020 Jan; 35(1): 92–105. Published online 2019 Nov 14. doi: 10.1002/jbmr.3875

PMCID:: PMC7004081

Article PDF–1.8M

Select item 42745172.

Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling

S. Tsukamoto, T. Mizuta, M. Fujimoto, S. Ohte, K. Osawa, A. Miyamoto, K. Yoneyama, E. Murata, A. Machiya, E. Jimi, S. Kokabu, T. Katagiri

Sci Rep. 2014; 4: 7596. Published online 2014 Dec 23. doi: 10.1038/srep07596

PMCID:: PMC4274517

Article PDF–1.3M

Select item 63500703.

Association of the gene polymorphisms of BMPR2, ACVRL1, SMAD9 and their interactions with the risk of essential hypertension in the Chinese Han population

Yunpeng Chen, Chenxi Ye, Jingwen Chen, Dongming Lin, Hao Wang, Shen Wang

Biosci Rep. 2019 Jan 31; 39(1): BSR20181217. Prepublished online 2019 Jan 7. Published online 2019 Jan 25. doi: 10.1042/BSR20181217

PMCID:: PMC6350070

Article PDF–964K

Select item 51110744.

Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation

Verena Dexheimer, Jessica Gabler, Katharina Bomans, Tanja Sims, Georg Omlor, Wiltrud Richter

Sci Rep. 2016; 6: 36655. Published online 2016 Nov 16. doi: 10.1038/srep36655

PMCID:: PMC5111074

Article PDF–1.9M

Select item 35644815.

Activated NF-κB in Bone Marrow Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients Inhibits Osteogenic Differentiation Through Downregulating Smad Signaling

Yu Tang, Hao Xie, Jinyun Chen, Linyu Geng, Haifeng Chen, Xia Li, Yayi Hou, Liwei Lu, Songtao Shi, Xiaofeng Zeng, Lingyun Sun

Stem Cells Dev. 2013 Feb 15; 22(4): 668–678. Published online 2012 Aug 16. doi: 10.1089/scd.2012.0226

PMCID:: PMC3564481

Article PDF–710K

Select item 35575286.

Inhibition of mTORC1 Kinase Activates Smads 1 and 5 but not Smad8 in Human Prostate Cancer Cells, Mediating Cytostatic Response to Rapamycin

Reema S. Wahdan-Alaswad, Kara L. Bane, Kyung Song, Dorjee T.N. Shola, Jorge A. Garcia, David Danielpour

Mol Cancer Res. Author manuscript; available in PMC 2013 Jan 28.

Published in final edited form as: Mol Cancer Res. 2012 Jun; 10(6): 821–833. Published online 2012 Mar 27. doi: 10.1158/1541-7786.MCR-11-0615

Correction in:: Mol Cancer Res. 2017 Nov 30

PMCID:: PMC3557528

Article PDF–3.3M

Select item 189297.

Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells

Wei Wang, Francesca V. Mariani, Richard M. Harland, Kunxin Luo

Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26): 14394–14399. doi: 10.1073/pnas.97.26.14394

PMCID:: PMC18929

Article PDF–306K

Select item 26732848.

BMP4-Smad Signaling Pathway Mediates Adriamycin-induced Premature Senescence in Lung Cancer Cells

Dongmei Su, Shan Zhu, Xuefang Han, Yunpeng Feng, Hui Huang, Guoling Ren, Lina Pan, Yu Zhang, Jun Lu, Baiqu Huang

J Biol Chem. 2009 May 1; 284(18): 12153–12164. doi: 10.1074/jbc.M807930200

PMCID:: PMC2673284

Article PDF–1.0M

Select item 44056389.

Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation

Fenfang Chen, Xia Lin, Pinglong Xu, Zhengmao Zhang, Yanzhen Chen, Chao Wang, Jiahuai Han, Bin Zhao, Mu Xiao, Xin-Hua Feng

Mol Cell Biol. 2015 May; 35(10): 1700–1711. Prepublished online 2015 Mar 9. Published online 2015 Apr 21. doi: 10.1128/MCB.00121-15

Correction in:: Mol Cell Biol. 2017 Sep 1; 37(17): e00287-17.

PMCID:: PMC4405638

Article PDF–3.6M

Select item 469717310.

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling

Xiaohua Yan, Hongwei Liao, Minzhang Cheng, Xiaojing Shi, Xia Lin, Xin-Hua Feng, Ye-Guang Chen

J Biol Chem. 2016 Jan 1; 291(1): 382–392. Published online 2015 Nov 10. doi: 10.1074/jbc.M115.694281

PMCID:: PMC4697173

Article PDF–3.0M

Select item 291331411.

Holding Their Own: The Noncanonical Roles of Smad Proteins

Loretta L. Hoover, Steven W. Kubalak

Sci Signal. Author manuscript; available in PMC 2010 Aug 2.

Published in final edited form as: Sci Signal. 2008 Nov 18; 1(46): pe48. Published online 2008 Nov 18. doi: 10.1126/scisignal.146pe48

PMCID:: PMC2913314

Article PDF–385K

Select item 258330612.

Endoglin Promotes Transforming Growth Factor β-mediated Smad 1/5/8 Signaling and Inhibits Endothelial Cell Migration through Its Association with GIPC

Nam Y. Lee, Bridgette Ray, Tam How, Gerard C. Blobe

J Biol Chem. 2008 Nov 21; 283(47): 32527–32533. doi: 10.1074/jbc.M803059200

PMCID:: PMC2583306

Article PDF–427K

Select item 2317413.

Vascular MADs: Two novel MAD-related genes selectively inducible by flow in human vascular endothelium

James N. Topper, Jiexing Cai, Yubin Qiu, Keith R. Anderson, Yong-Yao Xu, James D. Deeds, Roslyn Feeley, Carlos J. Gimeno, Elizabeth A. Woolf, Olga Tayber, Gail G. Mays, Barbara A. Sampson, Frederick J. Schoen, Michael A. Gimbrone, Jr., Dean Falb

Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17): 9314–9319. doi: 10.1073/pnas.94.17.9314

PMCID:: PMC23174

Article PDF–670K

Select item 52903114.

B-Cell Translocation Gene 2 (Btg2) Regulates Vertebral Patterning by Modulating Bone Morphogenetic Protein/Smad Signaling

Sean Park, Young Jae Lee, Ho-Jae Lee, Tsugio Seki, Kwon-Ho Hong, Joonil Park, Hideyuki Beppu, In Kyung Lim, Ji-Won Yoon, En Li, Seong-Jin Kim, S. Paul Oh

Mol Cell Biol. 2004 Dec; 24(23): 10256–10262. doi: 10.1128/MCB.24.23.10256-10262.2004

PMCID:: PMC529031

Article PDF–430K

Select item 31644415.

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

Akiko Hata, Giorgio Lagna, Joan Massagué, Ali Hemmati-Brivanlou

Genes Dev. 1998 Jan 15; 12(2): 186–197. doi: 10.1101/gad.12.2.186

PMCID:: PMC316444

Article PDF–831K

Select item 385535216.

Down-regulation of BMPR Axis during HIV-1 and Cocaine-mediated Pulmonary Smooth Muscle Hyperplasia: Implications for HRPAH

Pranjali Dalvi, Amy O’Brien-Ladner, Navneet K. Dhillon

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11): 10.1161/ATVBAHA.113.302054. Published online 2013 Sep 5. doi: 10.1161/ATVBAHA.113.302054

Correction in:: volume 34 on page e24

PMCID:: PMC3855352

Article PDF–1.3M

Select item 31674717.

Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes

Fang Liu, Celio Pouponnot, Joan Massagué

Genes Dev. 1997 Dec 1; 11(23): 3157–3167. doi: 10.1101/gad.11.23.3157

PMCID:: PMC316747

Article PDF–1.1M

Select item 373068418.

Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network

Daniel Nicklas, Leonor Saiz

J R Soc Interface. 2013 Sep 6; 10(86): 20130363. doi: 10.1098/rsif.2013.0363

PMCID:: PMC3730684

Article PDF–875K

Select item 510493719.

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin

Roy Baas, Ayestha Sijm, Hetty A. A. M. van Teeffelen, Robert van Es, Harmjan R. Vos, H. Th. Marc Timmers

J Biol Chem. 2016 Nov 11; 291(46): 24121–24132. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748582

PMCID:: PMC5104937

Article PDF–4.4M

Select item 426337120.

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu

PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819

PMCID:: PMC4263371

Article PDF–7.6M

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