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Select item 66324841.

A Pore Residue of the KCNQ3 Potassium M-Channel Subunit Controls Surface Expression

Juan Camilo Gómez-Posada, Ainhoa Etxeberría, Meritxell Roura-Ferrer, Pilar Areso, Marianela Masin, Ruth D. Murrell-Lagnado, Alvaro Villarroel

J Neurosci. 2010 Jul 7; 30(27): 9316–9323. doi: 10.1523/JNEUROSCI.0851-10.2010

PMCID:: PMC6632484

Article PDF–1024K

Select item 63634122.

Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening

Rene Barro-Soria

J Gen Physiol. 2019 Feb 4; 151(2): 247–257. doi: 10.1085/jgp.201812221

PMCID:: PMC6363412

Article PDF–1.9M

Select item 63021693.

Phosphatidylinositol 4,5-bisphosphate (PIP₂) regulates KCNQ3 K⁺ channels by interacting with four cytoplasmic channel domains

Frank S. Choveau, Victor De la Rosa, Sonya M. Bierbower, Ciria C. Hernandez, Mark S. Shapiro

J Biol Chem. 2018 Dec 14; 293(50): 19411–19428. Published online 2018 Oct 22. doi: 10.1074/jbc.RA118.005401

PMCID:: PMC6302169

Article PDF–4.6M

Select item 46870614.

The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K⁺ Current Amplitudes by Controlling Channel Trafficking

Frank S. Choveau, Jie Zhang, Sonya M. Bierbower, Ramaswamy Sharma, Mark S. Shapiro

PLoS One. 2015; 10(12): e0145367. Published online 2015 Dec 21. doi: 10.1371/journal.pone.0145367

PMCID:: PMC4687061

Article PDF–2.6M

Select item 34725495.

Regions of KCNQ K⁺ channels controlling functional expression

Frank S. Choveau, Mark S. Shapiro

Front Physiol. 2012; 3: 397. Published online 2012 Oct 16. doi: 10.3389/fphys.2012.00397

PMCID:: PMC3472549

Article PDF–1.1M

Select item 25865776.

Determinants within the Turret and Pore-Loop Domains of KCNQ3 K⁺ Channels Governing Functional Activity

Oleg Zaika, Ciria C. Hernandez, Manjot Bal, Gleb P. Tolstykh, Mark S. Shapiro

Biophys J. 2008 Dec 1; 95(11): 5121–5137. Published online 2008 Sep 12. doi: 10.1529/biophysj.108.137604

PMCID:: PMC2586577

Article PDF–2.0M

Select item 16824197.

Genetic heterogeneity in benign familial neonatal convulsions: identification of a new locus on chromosome 8q.

T B Lewis, R J Leach, K Ward, P O'Connell, S G Ryan

Am J Hum Genet. 1993 Sep; 53(3): 670–675.

PMCID:: PMC1682419

Summary Page Browse PDF–817K

Select item 67824568.

Two Types of K⁺ Channel Subunit, Erg1 and KCNQ2/3, Contribute to the M-Like Current in a Mammalian Neuronal Cell

A. A. Selyanko, J. K. Hadley, I. C. Wood, F. C. Abogadie, P. Delmas, N. J. Buckley, B. London, D. A. Brown

J Neurosci. 1999 Sep 15; 19(18): 7742–7756. doi: 10.1523/JNEUROSCI.19-18-07742.1999

PMCID:: PMC6782456

Article PDF–412K

Select item 67729289.

Reconstitution of Muscarinic Modulation of the KCNQ2/KCNQ3 K⁺ Channels That Underlie the Neuronal M Current

Mark S. Shapiro, John P. Roche, Edward J. Kaftan, Humberto Cruzblanca, Ken Mackie, Bertil Hille

J Neurosci. 2000 Mar 1; 20(5): 1710–1721. doi: 10.1523/JNEUROSCI.20-05-01710.2000

PMCID:: PMC6772928

Article PDF–210K

Select item 673004810.

Three Mechanisms Underlie KCNQ2/3 Heteromeric Potassium M-Channel Potentiation

Ainhoa Etxeberria, Irene Santana-Castro, M. Paz Regalado, Paloma Aivar, Alvaro Villarroel

J Neurosci. 2004 Oct 13; 24(41): 9146–9152. doi: 10.1523/JNEUROSCI.3194-04.2004

PMCID:: PMC6730048

Article PDF–275K

Select item 660556711.

Early-Onset Epileptic Encephalopathy Caused by Gain-of-Function Mutations in the Voltage Sensor of K_v7.2 and K_v7.3 Potassium Channel Subunits

Francesco Miceli, Maria Virginia Soldovieri, Paolo Ambrosino, Michela De Maria, Michele Migliore, Rosanna Migliore, Maurizio Taglialatela

J Neurosci. 2015 Mar 4; 35(9): 3782–3793. doi: 10.1523/JNEUROSCI.4423-14.2015

PMCID:: PMC6605567

Article PDF–3.6M

Select item 594584312.

Direct neurotransmitter activation of voltage-gated potassium channels

Rían W. Manville, Maria Papanikolaou, Geoffrey W. Abbott

Nat Commun. 2018; 9: 1847. Published online 2018 May 10. doi: 10.1038/s41467-018-04266-w

PMCID:: PMC5945843

Article PDF–2.7M

Select item 474275513.

The Sensorless Pore Module of Voltage-gated K⁺ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine

Ruhma Syeda, Jose S. Santos, Mauricio Montal

J Biol Chem. 2016 Feb 5; 291(6): 2931–2937. Published online 2015 Dec 1. doi: 10.1074/jbc.M115.683185

PMCID:: PMC4742755

Article PDF–1.7M

Select item 405057414.

Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P₂ and maintenance of KCNQ2/3 ion channel current

Eamonn J. Dickson, Jill B. Jensen, Bertil Hille

Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): E2281–E2290. Published online 2014 May 19. doi: 10.1073/pnas.1407133111

PMCID:: PMC4050574

Article PDF–1.8M

Select item 362713915.

Dysfunction of the Heteromeric K_V7.3/K_V7.5 Potassium Channel is Associated with Autism Spectrum Disorders

Mette Gilling, Hanne B. Rasmussen, Kirstine Calloe, Ana F. Sequeira, Marta Baretto, Guiomar Oliveira, Joana Almeida, Marlene B. Lauritsen, Reinhard Ullmann, Susanne E. Boonen, Karen Brondum-Nielsen, Vera M. Kalscheuer, Zeynep Tümer, Astrid M. Vicente, Nicole Schmitt, Niels Tommerup

Front Genet. 2013; 4: 54. Prepublished online 2012 Dec 30. Published online 2013 Apr 16. doi: 10.3389/fgene.2013.00054

PMCID:: PMC3627139

Article PDF–2.8M

Select item 357952116.

Rapid Chemically Induced Changes of PtdIns(4,5)P₂ Gate KCNQ Ion Channels

Byung-Chang Suh, Takanari Inoue, Tobias Meyer, Bertil Hille

Science. Author manuscript; available in PMC 2013 Feb 22.

Published in final edited form as: Science. 2006 Dec 1; 314(5804): 1454–1457. Published online 2006 Sep 21. doi: 10.1126/science.1131163

PMCID:: PMC3579521

Article PDF–2.8M

Select item 332093517.

The Kv7.2/Kv7.3 Heterotetramer Assembles with a Random Subunit Arrangement

Andrew P. Stewart, Juan Camilo Gómez-Posada, Jessica McGeorge, Maral J. Rouhani, Alvaro Villarroel, Ruth D. Murrell-Lagnado, J. Michael Edwardson

J Biol Chem. 2012 Apr 6; 287(15): 11870–11877. Published online 2012 Feb 13. doi: 10.1074/jbc.M111.336511

PMCID:: PMC3320935

Article PDF–2.1M

Select item 318225018.

Kv7 Channels Can Function without Constitutive Calmodulin Tethering

Juan Camilo Gómez-Posada, Paloma Aivar, Araitz Alberdi, Alessandro Alaimo, Ainhoa Etxeberría, Juncal Fernández-Orth, Teresa Zamalloa, Meritxell Roura-Ferrer, Patricia Villace, Pilar Areso, Oscar Casis, Alvaro Villarroel

PLoS One. 2011; 6(9): e25508. Published online 2011 Sep 28. doi: 10.1371/journal.pone.0025508