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Select item 96891331.

Expression of IRAK1 in Hepatocellular Carcinoma, Its Clinical Significance, and Docking Characteristics with Selected Natural Compounds

Chaoying Song, Xinyu Gu, Ruifang Li

Curr Oncol. 2022 Nov; 29(11): 8904–8916. Published online 2022 Nov 18. doi: 10.3390/curroncol29110700

PMCID:: PMC9689133

Article PDF–2.5M

Select item 96373242.

Interleukin Receptor Associated Kinase 1 Signaling and Its Association with Cardiovascular Diseases

Youjing Zheng, Jia-Qiang He

Rev Cardiovasc Med. Author manuscript; available in PMC 2022 Nov 6.

Published in final edited form as: Rev Cardiovasc Med. 2022 Mar 12; 23(3): 97. doi: 10.31083/j.rcm2303097

PMCID:: PMC9637324

Article PDF–829K

Select item 96283283.

IRAK1 Duplication in MECP2 Duplication Syndrome Does Not Increase Canonical NF-κB–Induced Inflammation

Ilona Gottschalk, Uwe Kölsch, Dimitrios L. Wagner, Jonas Kath, Stefania Martini, Renate Krüger, Anne Puel, Jean-Laurent Casanova, Aleksandra Jezela-Stanek, Rainer Rossi, Salima El Chehadeh, Hilde Van Esch, Horst von Bernuth

J Clin Immunol. 2023; 43(2): 421–439. Published online 2022 Nov 2. doi: 10.1007/s10875-022-01390-7

PMCID:: PMC9628328

Article PDF–1.5M

Select item 88062474.

Effect of sodium butyrate regulating IRAK1 (interleukin-1 receptor-associated kinase 1) on visceral hypersensitivity in irritable bowel syndrome and its mechanism

Yuqin He, Yan Tan, Jianru Zhu, Xiaofeng Wu, Zhiyong Huang, Hengsheng Chen, Min Yang, Dongfeng Chen

Bioengineered. 2021; 12(1): 1436–1444. Published online 2021 Apr 27. doi: 10.1080/21655979.2021.1920324

PMCID:: PMC8806247

Article PDF–716K

Select item 79972855.

The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling

V. Douglas Landers, Daniel W. Wilkey, Michael L. Merchant, Thomas C. Mitchell, Kevin J. Sokoloski

Viruses. 2021 Mar; 13(3): 377. Published online 2021 Feb 27. doi: 10.3390/v13030377

PMCID:: PMC7997285

Article PDF–3.9M

Select item 73667966.

IRAK1 is a critical mediator of inflammation induced preterm birth

Viral G Jain, Fansheng Kong, Suhas G Kallapur, Pietro Presicce, Paranthaman Senthamaraikannnan, Monica Cappelletti, Claire A. Chougnet, Sandip Bhattacharyya, Chandrashekhar Pasare, Louis J Muglia

J Immunol. Author manuscript; available in PMC 2020 Nov 15.

Published in final edited form as: J Immunol. 2020 May 15; 204(10): 2651–2660. Published online 2020 Apr 1. doi: 10.4049/jimmunol.1901368

PMCID:: PMC7366796

Article PDF–780K

Select item 71993997.

Interleukin-1 Receptor-Associated Kinase (IRAK) Signaling in Kaposi Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma

Jedediah Seltzer, Razia Moorad, Jason M. Schifano, Justin T. Landis, Dirk P. Dittmer

J Virol. 2020 May; 94(10): e02123-19. Prepublished online 2020 Mar 11. Published online 2020 May 4. doi: 10.1128/JVI.02123-19

PMCID:: PMC7199399

Article PDF–4.1M

Select item 69525908.

X-linked IRAK1 polymorphism is associated with sex-related differences in polymorphonuclear granulocyte and monocyte activation and response variabilities

Yong Qin, Geber Peña, Patrick Morcillo, Sukhwinder Singh, Anne C. Mosenthal, David H. Livingston, Zoltan Spolarics

Shock. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Shock. 2020 Apr; 53(4): 434–441. doi: 10.1097/SHK.0000000000001404

PMCID:: PMC6952590

Article PDF–1.4M

Select item 68991009.

Association of IRAK1 Gene Polymorphism rs3027898 With Papillary Cancer Restricted to the Thyroid Gland: A Pilot Study

ANTHOULA CHATZIKYRIAKIDOU, ANGELIKI CHORTI, THEODOSIOS PAPAVRAMIDIS

In Vivo. 2019 Nov-Dec; 33(6): 2281–2285. Published online 2019 Nov 3. doi: 10.21873/invivo.11734

PMCID:: PMC6899100

Article PDF–98K

Select item 655852010.

Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes

Mona M. Hosseini, Stephen E. Kurtz, Sherif Abdelhamed, Shawn Mahmood, Monika A. Davare, Andy Kaempf, Johannes Elferich, Jason E. McDermott, Tao Liu, Samuel H. Payne, Ujwal Shinde, Karin D. Rodland, Motomi Mori, Brian J. Druker, Jack W. Singer, Anupriya Agarwal

Leukemia. Author manuscript; available in PMC 2019 Jun 11.

Published in final edited form as: Leukemia. 2018 Nov; 32(11): 2374–2387. Published online 2018 Mar 29. doi: 10.1038/s41375-018-0112-2

PMCID:: PMC6558520

Article PDF–2.4M

Select item 527848111.

Inherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblasts

Erika Della Mina, Alessandro Borghesi, Hao Zhou, Salim Bougarn, Sabri Boughorbel, Laura Israel, Ilaria Meloni, Maya Chrabieh, Yun Ling, Yuval Itan, Alessandra Renieri, Iolanda Mazzucchelli, Sabrina Basso, Piero Pavone, Raffaele Falsaperla, Roberto Ciccone, Rosa Maria Cerbo, Mauro Stronati, Capucine Picard, Orsetta Zuffardi, Laurent Abel, Damien Chaussabel, Nico Marr, Xiaoxia Li, Jean-Laurent Casanova, Anne Puel

Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): E514–E523. Published online 2017 Jan 9. doi: 10.1073/pnas.1620139114

PMCID:: PMC5278481

Article PDF–1.6M

Select item 502054612.

Targeting interleukin-1 receptor-associated kinase 1 for human hepatocellular carcinoma

Ning Li, Jinhua Jiang, Jing Fu, Ting Yu, Bibo Wang, Wenhao Qin, An Xu, Mengchao Wu, Yao Chen, Hongyang Wang

J Exp Clin Cancer Res. 2016; 35(1): 140. Published online 2016 Sep 13. doi: 10.1186/s13046-016-0413-0

PMCID:: PMC5020546

Article PDF–2.9M

Select item 479123913.

IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival

Allie K. Adams, Lyndsey C. Bolanos, Phillip J. Dexheimer, Rebekah A. Karns, Bruce J. Aronow, Kakajan Komurov, Anil G. Jegga, Keith A. Casper, Yash J. Patil, Keith M. Wilson, Daniel T. Starczynowski, Susanne I. Wells

Oncotarget. 2015 Dec 22; 6(41): 43395–43407. Published online 2015 Oct 26. doi: 10.18632/oncotarget.6028

PMCID:: PMC4791239

Article PDF–5.6M

Select item 464008314.

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

Zhen Ning Wee, Siti Maryam J. M. Yatim, Vera K Kohlbauer, Min Feng, Jian Yuan Goh, Bao Yi, Puay Leng Lee, Songjing Zhang, Pan Pan Wang, Elgene Lim, Wai Leong Tam, Yu Cai, Henrik J Ditzel, Dave S. B. Hoon, Ern Yu Tan, Qiang Yu

Nat Commun. 2015; 6: 8746. Published online 2015 Oct 27. doi: 10.1038/ncomms9746

Correction in:: Nat Commun. 2015; 6: 10054.

PMCID:: PMC4640083

Article PDF–4.6M

Select item 427060315.

Expression of IRAK1 in lung cancer tissues and its clinicopathological significance: a microarray study

Xiuling Zhang, Yiwu Dang, Ping Li, Minhua Rong, Gang Chen

Int J Clin Exp Pathol. 2014; 7(11): 8096–8104. Published online 2014 Oct 15.

PMCID:: PMC4270603

Article PDF–1.1M

Select item 422613216.

Interleukin 1 receptor-associated kinase 1 (IRAK1) mutation is a common, essential driver for Kaposi sarcoma herpesvirus lymphoma

Dongmei Yang, Wuguo Chen, Jie Xiong, Carly J. Sherrod, David H. Henry, Dirk P. Dittmer

Proc Natl Acad Sci U S A. 2014 Nov 4; 111(44): E4762–E4768. Published online 2014 Oct 23. doi: 10.1073/pnas.1405423111

Correction in:: Proc Natl Acad Sci U S A. 2015 May 5; 112(18): E2412.

PMCID:: PMC4226132

Article PDF–1.1M

Select item 415972917.

X-Chromosome Linked IRAK-1 Polymorphism Is A Strong Predictor Of Multiple Organ Failure And Mortality Post-Injury

Jason L. Sperry, Samuel Zolin, Brian S. Zuckerbraun, Yoram Vodovotz, Rami Namas, Matthew D. Neal, Robert E. Ferrell, Matthew R. Rosengart, Andrew B. Peitzman, Timothy R. Billiar

Ann Surg. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Ann Surg. 2014 Oct; 260(4): 698–705. doi: 10.1097/SLA.0000000000000918

PMCID:: PMC4159729

Article PDF–337K

Select item 266297318.

Variant IRAK-1 Haplotype Is Associated with Increased Nuclear Factor–κB Activation and Worse Outcomes in Sepsis

John Arcaroli, Eliezer Silva, James P. Maloney, Qianbin He, Daiva Svetkauskaite, James R. Murphy, Edward Abraham

Am J Respir Crit Care Med. 2006 Jun 15; 173(12): 1335–1341. Published online 2006 Mar 9. doi: 10.1164/rccm.200603-341OC

PMCID:: PMC2662973

Article PDF–165K

Select item 262888019.

Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1

Valerie Albrecht, Thomas PJ Hofer, Brian Foxwell, Marion Frankenberger, Loems Ziegler-Heitbrock

BMC Immunol. 2008; 9: 69. Published online 2008 Nov 24. doi: 10.1186/1471-2172-9-69

PMCID:: PMC2628880

Article PDF–413K

Select item 867026620.

IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies

Baohuan Cai, Yun Liu, Yating Chong, Hualei Zhang, Atsuko Matsunaga, Xuexiu Fang, Rafal Pacholczyk, Gang Zhou, John K. Cowell, Tianxiang Hu

Mol Cancer. 2021; 20: 165. Published online 2021 Dec 14. doi: 10.1186/s12943-021-01460-1

PMCID:: PMC8670266

Article PDF–13M

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