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Select item 75212501.

Association of TLX1 gene polymorphisms with the risk of acute lymphoblastic leukemia and B lineage acute lymphoblastic leukemia in Han Chinese children

Endian Mei, Xubin Wei, Jiadong Gao, Xiaolong Tian, Wei Li, Li Liu, Cheng Qian

J Clin Lab Anal. 2020 Sep; 34(9): e23414. Published online 2020 Jun 2. doi: 10.1002/jcla.23414

PMCID:: PMC7521250

Article PDF–438K

Select item 62693032.

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

Karen Verboom, Wouter Van Loocke, Pieter-Jan Volders, Bieke Decaesteker, Francisco Avila Cobos, Simon Bornschein, Charles E. de Bock, Zeynep Kalender Atak, Emmanuelle Clappier, Stein Aerts, Jan Cools, Jean Soulier, Tom Taghon, Pieter Van Vlierberghe, Jo Vandesompele, Frank Speleman, Kaat Durinck

Haematologica. 2018 Dec; 103(12): e585–e589. doi: 10.3324/haematol.2018.190587

PMCID:: PMC6269303

Article PDF–1.2M

Select item 38119003.

G-Quadruplex Structures Formed at the HOX11 Breakpoint Region Contribute to Its Fragility during t(10;14) Translocation in T-Cell Leukemia

Mridula Nambiar, Mrinal Srivastava, Vidya Gopalakrishnan, Sritha K. Sankaran, Sathees C. Raghavan

Mol Cell Biol. 2013 Nov; 33(21): 4266–4281. doi: 10.1128/MCB.00540-13

PMCID:: PMC3811900

Article PDF–4.3M

Select item 29747904.

The TLX1 oncogene drives aneuploidy in T-cell transformation

Kim De Keersmaecker, Pedro Jose Real, Giusy Della Gatta, Teresa Palomero, Maria Luisa Sulis, Valeria Tosello, Pieter Van Vlierberghe, Kelly Barnes, Mireia Castillo, Xavier Sole, Michael Hadler, Jack Lenz, Peter D. Aplan, Michelle Kelliher, Barbara L. Kee, Pier Paolo Pandolfi, Dietmar Kappes, Fotini Gounari, Howard Petrie, Joni Van der Meulen, Frank Speleman, Elisabeth Paietta, Janis Racevskis, Peter H. Wiernik, Jacob M. Rowe, Jean Soulier, David Avran, Hélène Cavé, Nicole Dastugue, Susana Raimondi, Jules P.P. Meijerink, Carlos Cordon-Cardo, Andrea Califano, Adolfo A. Ferrando

Nat Med. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Nat Med. 2010 Nov; 16(11): 1321–1327. Published online 2010 Oct 24. doi: 10.1038/nm.2246

PMCID:: PMC2974790

Article PDF–1.9M

Select item 29139835.

TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells

Irene Riz, Teresa S Hawley, Truong V Luu, Norman H Lee, Robert G Hawley

Mol Cancer. 2010; 9: 181. Published online 2010 Jul 9. doi: 10.1186/1476-4598-9-181

PMCID:: PMC2913983

Article PDF–1.6M

Select item 24087536.

G₁/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia

Irene Riz, Robert G. Hawley

Oncogene. Author manuscript; available in PMC 2008 Jun 2.

Published in final edited form as: Oncogene. 2005 Aug 25; 24(36): 5561–5575. doi: 10.1038/sj.onc.1208727

PMCID:: PMC2408753

Article PDF–3.1M

Select item 19553827.

TLX1/HOX11-induced hematopoietic differentiation blockade

I Riz, SS Akimov, SS Eaker, KK Baxter, HJ Lee, L Mariño-Ramírez, D Landsman, TS Hawley, RG Hawley

Oncogene. Author manuscript; available in PMC 2007 Aug 28.

Published in final edited form as: Oncogene. 2007 Jun 14; 26(28): 4115–4123. Published online 2007 Jan 8. doi: 10.1038/sj.onc.1210185

PMCID:: PMC1955382

Article PDF–601K

Select item 4530038.

The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein.

M Lu, Z Y Gong, W F Shen, A D Ho

EMBO J. 1991 Oct; 10(10): 2905–2910. doi: 10.1002/j.1460-2075.1991.tb07840.x

PMCID:: PMC453003

Summary Page Browse PDF–1.0M

Select item 60134229.

Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription

Lin Jia, Dinglan Wu, Yuliang Wang, Wenxing You, Zhu Wang, Lijia Xiao, Ganhui Cai, Zhenyu Xu, Chang Zou, Fei Wang, Jeremy Yuen-Chun Teoh, Chi-Fai Ng, Shan Yu, Franky L. Chan

Oncogene. 2018; 37(25): 3340–3355. Published online 2018 Mar 20. doi: 10.1038/s41388-018-0198-z

PMCID:: PMC6013422

Article PDF–4.5M

Select item 303389810.

Transient Responses to NOTCH and TLX1/HOX11 Inhibition in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Lesley A. Rakowski, Erica A. Lehotzky, Mark Y. Chiang

PLoS One. 2011; 6(2): e16761. Published online 2011 Feb 4. doi: 10.1371/journal.pone.0016761

PMCID:: PMC3033898

Article PDF–1.0M

Select item 279504911.

Hematopoietic Immortalizing Function of the NKL-Subclass Homeobox Gene TLX1

Lynnsey A. Zweier-Renn, Teresa S. Hawley, Sandra Burkett, Ali Ramezani, Irene Riz, Rima L. Adler, Dennis D. Hickstein, Robert G. Hawley

Genes Chromosomes Cancer. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Genes Chromosomes Cancer. 2010 Feb; 49(2): 119–131. doi: 10.1002/gcc.20725

PMCID:: PMC2795049

Article PDF–370K

Select item 549581312.

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation

Boris Novakovic, Thierry Fournier, Lynda K. Harris, Joanna James, Claire T. Roberts, Hannah E. J. Yong, Bill Kalionis, Danièle Evain-Brion, Peter R. Ebeling, Euan M. Wallace, Richard Saffery, Padma Murthi

Sci Rep. 2017; 7: 4523. Published online 2017 Jul 3. doi: 10.1038/s41598-017-04776-5

PMCID:: PMC5495813

Article PDF–2.7M

Select item 537120313.

Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer

Tyler McInnes, Donghui Zou, Dasari S. Rao, Francesca M. Munro, Vicky L. Phillips, John L. McCall, Michael A. Black, Anthony E. Reeve, Parry J. Guilford

BMC Cancer. 2017; 17: 228. Published online 2017 Mar 28. doi: 10.1186/s12885-017-3226-4

PMCID:: PMC5371203

Article PDF–855K

Select item 5261814.

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24.

M A Kennedy, R Gonzalez-Sarmiento, U R Kees, F Lampert, N Dear, T Boehm, T H Rabbitts

Proc Natl Acad Sci U S A. 1991 Oct 15; 88(20): 8900–8904. doi: 10.1073/pnas.88.20.8900

PMCID:: PMC52618

Summary Page Browse PDF–1.0M

Select item 329803615.

Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL

Giusy Della Gatta, Teresa Palomero, Arianne Perez-Garcia, Alberto Ambesi-Impiombato, Mukesh Bansal, Zachary W. Carpenter, Kim De Keersmaecker, Xavier Sole, Luyao Xu, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, Jules P Meijerink, Andrea Califano, Adolfo A. Ferrando

Nat Med. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: Nat Med. 2012 Mar; 18(3): 436–440. Published online 2012 Feb 26. doi: 10.1038/nm.2610

PMCID:: PMC3298036

Article PDF–1.2M

Select item 265441316.

Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors

Irene Riz, Hyo Jung Lee, Kristin K. Baxter, Reza Behnam, Teresa S. Hawley, Robert G. Hawley

Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Mar 6.

Published in final edited form as: Biochem Biophys Res Commun. 2009 Mar 6; 380(2): 361–365. Published online 2009 Jan 23. doi: 10.1016/j.bbrc.2009.01.099

PMCID:: PMC2654413

Article PDF–969K

Select item 14075317.

The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth

Ivan Topisirovic, Biljana Culjkovic, Natalie Cohen, Jacqueline M. Perez, Lucy Skrabanek, Katherine L.B. Borden

EMBO J. 2003 Feb 3; 22(3): 689–703. doi: 10.1093/emboj/cdg069

PMCID:: PMC140753

Article PDF–576K

Select item 609787618.

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

Marlies Vanden Bempt, Sofie Demeyer, Michaël Broux, Jolien De Bie, Simon Bornschein, Nicole Mentens, Roel Vandepoel, Ellen Geerdens, Enrico Radaelli, Beat C. Bornhauser, Andreas E. Kulozik, Jules P. Meijerink, Jean-Pierre Bourquin, Charles E. de Bock, Jan Cools

Cancer Cell. 2018 Aug 13; 34(2): 271–285.e7. doi: 10.1016/j.ccell.2018.07.007

PMCID:: PMC6097876

Article

Select item 4652519.

The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.

T N Dear, I Sanchez-Garcia, T H Rabbitts

Proc Natl Acad Sci U S A. 1993 May 15; 90(10): 4431–4435. doi: 10.1073/pnas.90.10.4431

PMCID:: PMC46525

Summary Page Browse PDF–1.2M

Select item 988113620.

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke

Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188

PMCID:: PMC9881136

Article PDF–4.4M

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