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Items: 1 to 20 of 138

1.
Downregulation of DROSHA: Could It Affect miRNA Biogenesis in Endometriotic Menstrual Blood Mesenchymal Stem Cells?
Ana Clara Lagazzi Cressoni, Letícia B. C. Penariol, Cristiana Carolina Padovan, Maristela D. Orellana, Júlio Cesar Rosa-e-Silva, Omero Benedicto Poli-Neto, Rui Alberto Ferriani, Cláudia Cristina Paro de Paz, Juliana Meola
Int J Mol Sci. 2023 Mar; 24(6): 5963. Published online 2023 Mar 22. doi: 10.3390/ijms24065963
PMCID:
PMC10057010
ArticlePDF–686K
2.
Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis
I. Ormenezi, A. Ribeiro-Silva, J.C. Rosa-e-Silva, J. Meola, F.J. Candido-dos-Reis, O.B. Poli-Neto
Braz J Med Biol Res. 2022; 55: e12375. Published online 2022 Dec 12. doi: 10.1590/1414-431X2022e12375
PMCID:
PMC9744411
ArticlePDF–785K
3.
p38 MAPK‐mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta‐induced neuronal stress in Alzheimer's disease
Haidong Xu, Xiaolei Liu, Wenming Li, Ye Xi, Peng Su, Bo Meng, Xiaoyun Shao, Beisha Tang, Qian Yang, Zixu Mao
Aging Cell. 2021 Oct; 20(10): e13434. Published online 2021 Sep 16. doi: 10.1111/acel.13434
PMCID:
PMC8521488
ArticlePDF–2.5M
4.
Towards Understanding the Pathogenicity of DROSHA Mutations in Oncohematology
Dmitrii S. Bug, Artem V. Tishkov, Ivan S. Moiseev, Yuri B. Porozov, Natalia V. Petukhova
Cells. 2021 Sep; 10(9): 2357. Published online 2021 Sep 8. doi: 10.3390/cells10092357
PMCID:
PMC8471307
ArticlePDF–1.9M
5.
Tissue-specific and transcription-dependent mechanisms regulate primary microRNA processing efficiency of the human chromosome 19 MicroRNA cluster
Ábel Fóthi, Orsolya Biró, Zsuzsa Erdei, Ágota Apáti, Tamás I. Orbán
RNA Biol. 2021; 18(8): 1170–1180. Published online 2020 Oct 23. doi: 10.1080/15476286.2020.1836457
PMCID:
PMC8244754
ArticlePDF–4.3M
6.
Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells
Lisheng Dai, Lillian Hallmark, Xavier Bofill De Ros, Howard Crouch, Sean Chen, Tony Shi, Acong Yang, Chuanjiang Lian, Yongmei Zhao, Bao Tran, Shuo Gu
RNA Biol. 2020; 17(11): 1603–1612. Published online 2020 Aug 30. doi: 10.1080/15476286.2020.1813439
PMCID:
PMC7567492
ArticlePDF–3.8M
7.
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis
Soo Jung Cho, Kyoung Sook Hong, Ji Hun Jeong, Mihye Lee, Augustine M. K. Choi, Heather W. Stout-Delgado, Jong-Seok Moon
Cells. 2019 Aug; 8(8): 938. Published online 2019 Aug 20. doi: 10.3390/cells8080938
PMCID:
PMC6721825
ArticlePDF–3.9M
8.
Deregulation of Drosha in the pathogenesis of hereditary hemorrhagic telangiectasia
Akiko Hata, Giorgio Lagna
Curr Opin Hematol. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Curr Opin Hematol. 2019 May; 26(3): 161–169. doi: 10.1097/MOH.0000000000000493
PMCID:
PMC6476316
ArticlePDF–790K
9.
Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
Wei-Ting Lu, Ben R. Hawley, George L. Skalka, Robert A. Baldock, Ewan M. Smith, Aldo S. Bader, Michal Malewicz, Felicity Z. Watts, Ania Wilczynska, Martin Bushell
Nat Commun. 2018; 9: 532. Published online 2018 Feb 7. doi: 10.1038/s41467-018-02893-x
PMCID:
PMC5803274
ArticlePDF–2.7M
10.
The evidence for a microRNA product of human DROSHA gene
Peter Mechtler, Sydney Johnson, Hannah Slabodkin, Amir B. Cohanim, Leonid Brodsky, Eugene S. Kandel
RNA Biol. 2017; 14(11): 1508–1513. Published online 2017 Sep 5. doi: 10.1080/15476286.2017.1342934
PMCID:
PMC5785223
ArticlePDF–563K
11.
Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma
Seyed Mehdi Jafarnejad, Cecilia Sjoestroem, Magdalena Martinka, Gang Li
Mod Pathol. Author manuscript; available in PMC 2016 Sep 15.
Published in final edited form as: Mod Pathol. 2013 Jul; 26(7): 902–910. Published online 2013 Feb 1. doi: 10.1038/modpathol.2012.225
PMCID:
PMC5025290
ArticlePDF–1.0M
12.
A central role for the primary microRNA stem in guiding the position and efficiency of Drosha processing of a viral pri-miRNA
James M. Burke, Demetra P. Kelenis, Rodney P. Kincaid, Christopher S. Sullivan
RNA. 2014 Jul; 20(7): 1068–1077. doi: 10.1261/rna.044537.114
PMCID:
PMC4114686
ArticlePDF–1.0M
13.
Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour
Giovana T. Torrezan, Elisa N. Ferreira, Adriana M. Nakahata, Bruna D. F. Barros, Mayra T. M. Castro, Bruna R. Correa, Ana C. V. Krepischi, Eloisa H. R. Olivieri, Isabela W. Cunha, Uri Tabori, Paul E. Grundy, Cecilia M. L. Costa, Beatriz de Camargo, Pedro A. F. Galante, Dirce M. Carraro
Nat Commun. 2014 Jun 9; 5: 4039. Published online 2014 Jun 9. doi: 10.1038/ncomms5039
PMCID:
PMC4062040
ArticlePDF–1.3M
14.
Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon
Mallory A. Havens, Ashley A. Reich, Michelle L. Hastings
PLoS Genet. 2014 May; 10(5): e1004312. Published online 2014 May 1. doi: 10.1371/journal.pgen.1004312
PMCID:
PMC4006729
ArticlePDF–4.7M
15.
miRNA sensitivity to Drosha levels correlates with pre-miRNA secondary structure
Henrik Sperber, Alan Beem, Sandra Shannon, Ross Jones, Pratyusha Banik, Yu Chen, Sherman Ku, Gabriele Varani, Shuyuan Yao, Hannele Ruohola-Baker
RNA. 2014 May; 20(5): 621–631. doi: 10.1261/rna.043943.113
PMCID:
PMC3988564
ArticlePDF–479K
16.
Drosha Regulates Gene Expression Independently of RNA Cleavage Function
Natalia Gromak, Martin Dienstbier, Sara Macias, Mireya Plass, Eduardo Eyras, Javier F. Cáceres, Nicholas J. Proudfoot
Cell Rep. 2013 Dec 26; 5(6): 1499–1510. Published online 2013 Dec 19. doi: 10.1016/j.celrep.2013.11.032
Correction in:
Cell Rep. 2014 Jun 12; 7(5): 1753–1754.
PMCID:
PMC3898267
ArticlePDF–1.7M
17.
Lower and upper stem–single-stranded RNA junctions together determine the Drosha cleavage site
Hongming Ma, Yonggan Wu, Jang-Gi Choi, Haoquan Wu
Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51): 20687–20692. Published online 2013 Dec 2. doi: 10.1073/pnas.1311639110
PMCID:
PMC3870748
ArticlePDF–1.2M
18.
Acetylation of Drosha on the N-Terminus Inhibits Its Degradation by Ubiquitination
Xiaoli Tang, Sicheng Wen, Dong Zheng, Lynne Tucker, Lulu Cao, Dennis Pantazatos, Steven F. Moss, Bharat Ramratnam
PLoS One. 2013; 8(8): e72503. Published online 2013 Aug 29. doi: 10.1371/journal.pone.0072503
PMCID:
PMC3757024
ArticlePDF–2.1M
19.
Ensemble Analysis of Primary miRNA Structure Reveals an Extensive Capacity to Deform near the Drosha Cleavage Site
Kaycee A. Quarles, Debashish Sahu, Mallory A. Havens, Ellen R. Forsyth, Christopher Wostenberg, Michelle L. Hastings, Scott A. Showalter
Biochemistry. Author manuscript; available in PMC 2014 Feb 5.
Published in final edited form as: Biochemistry. 2013 Feb 5; 52(5): 795–807. Published online 2013 Jan 18. doi: 10.1021/bi301452a
PMCID:
PMC3565094
ArticlePDF–3.0M
20.
The regulatory effect of miRNAs is a heritable genetic trait in humans
Paul Geeleher, Stephanie R Huang, Eric R Gamazon, Aaron Golden, Cathal Seoighe
BMC Genomics. 2012; 13: 383. Published online 2012 Aug 10. doi: 10.1186/1471-2164-13-383
PMCID:
PMC3532363
ArticlePDF–810K

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