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Select item 77383691.

YTHDF3 Induces the Translation of m⁶A-enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis

Guoqiang Chang, Lei Shi, Youqiong Ye, Hailing Shi, Lixian Zeng, Shweta Tiwary, Jason T. Huse, Lei Huo, Li Ma, Yongjie Ma, Sicong Zhang, Jianwei Zhu, Victoria Xie, Peng Li, Leng Han, Chuan He, Suyun Huang

Cancer Cell. Author manuscript; available in PMC 2021 Dec 14.

Published in final edited form as: Cancer Cell. 2020 Dec 14; 38(6): 857–871.e7. Published online 2020 Oct 29. doi: 10.1016/j.ccell.2020.10.004

PMCID:: PMC7738369

Article PDF–2.4M

Select item 70628052.

Cytoplasmic m¹A reader YTHDF3 inhibits trophoblast invasion by downregulation of m¹A-methylated IGF1R

Qingliang Zheng, Haili Gan, Fenglian Yang, Yongli Yao, Fan Hao, Ling Hong, Liping Jin

Cell Discov. 2020; 6: 12. Published online 2020 Mar 10. doi: 10.1038/s41421-020-0144-4

PMCID:: PMC7062805

Article PDF–1.8M

Select item 107976973.

The inhibition of YTHDF3/m⁶A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer

Sheng Zhong, Quanwei Guo, Xiaona Chen, Xiaomin Luo, Yufei Long, Tuotuo Chong, Ming Ye, Hui He, Anwei Lu, Keyi Ao, Minuo Yin, Aimin Xu, Xin Li, Yi Hao, Xia Guo

Int J Biol Sci. 2024; 20(3): 916–936. Published online 2024 Jan 12. doi: 10.7150/ijbs.87203

PMCID:: PMC10797697

Article PDF–13M

Select item 92110714.

N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 3 or insulin like growth factor 2 mRNA binding protein 2 knockdown protects human bronchial epithelial cells from hypoxia/reoxygenation injury by inactivating p38 MAPK, AKT, ERK1/2, and NF-κB pathways

Kun Xiao, Pengfei Liu, Peng Yan, Yanxin Liu, Licheng Song, Yuhong Liu, Lixin Xie

Bioengineered. 2022; 13(5): 11973–11986. Published online 2022 May 19. doi: 10.1080/21655979.2021.1999550

PMCID:: PMC9211071

Article PDF–5.3M

Select item 82579095.

Development and validation of m6A regulators’ prognostic significance for endometrial cancer

Xuecheng Pang, Xiang Zhang, Yue Huang, Sumin Qian

Medicine (Baltimore) 2021 Jul 2; 100(26): e26551. Published online 2021 Jul 2. doi: 10.1097/MD.0000000000026551

PMCID:: PMC8257909

Article PDF–1.8M

Select item 80922056.

Enterovirus 2A^pro Cleavage of the YTHDF m⁶A Readers Implicates YTHDF3 as a Mediator of Type I Interferon-Driven JAK/STAT Signaling

Jonathan P. Kastan, Martine W. Tremblay, Michael C. Brown, Joseph D. Trimarco, Elena Y. Dobrikova, Mikhail I. Dobrikov, Matthias Gromeier

mBio. 2021 Mar-Apr; 12(2): e00116-21. Published online 2021 Apr 13. doi: 10.1128/mBio.00116-21

PMCID:: PMC8092205

Article PDF–1.9M

Select item 64169607.

m⁶A RNA modification and its writer/reader VIRMA/YTHDF3 in testicular germ cell tumors: a role in seminoma phenotype maintenance

João Lobo, Ana Laura Costa, Mariana Cantante, Rita Guimarães, Paula Lopes, Luís Antunes, Isaac Braga, Jorge Oliveira, Mattia Pelizzola, Rui Henrique, Carmen Jerónimo

J Transl Med. 2019; 17: 79. Published online 2019 Mar 12. doi: 10.1186/s12967-019-1837-z

PMCID:: PMC6416960

Article PDF–3.0M

Select item 84209748.

Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration

Kuan Hu, Lei Yao, Yuanliang Yan, Lei Zhou, Juanni Li

Dis Markers. 2021; 2021: 2789481. Published online 2021 Aug 26. doi: 10.1155/2021/2789481

PMCID:: PMC8420974

Article PDF–2.5M

Select item 75082569.

A Unified Model for the Function of YTHDF Proteins in Regulating m⁶A-Modified mRNA

Sara Zaccara, Samie R. Jaffrey

Cell. Author manuscript; available in PMC 2021 Jun 25.

Published in final edited form as: Cell. 2020 Jun 25; 181(7): 1582–1595.e18. Published online 2020 Jun 2. doi: 10.1016/j.cell.2020.05.012

PMCID:: PMC7508256

Article PDF–2.1M

Select item 744272710.

m⁶A-binding YTHDF proteins promote stress granule formation

Ye Fu, Xiaowei Zhuang

Nat Chem Biol. Author manuscript; available in PMC 2020 Nov 25.

Published in final edited form as: Nat Chem Biol. 2020 Sep; 16(9): 955–963. Published online 2020 May 25. doi: 10.1038/s41589-020-0524-y

PMCID:: PMC7442727

Article PDF–1.0M

Select item 666291511.

m⁶A enhances the phase separation potential of mRNA

Ryan J. Ries, Sara Zaccara, Pierre Klein, Anthony Olarerin-George, Sim Namkoong, Brian F. Pickering, Deepak P. Patil, Hojoong Kwak, Jun Hee Lee, Samie R. Jaffrey

Nature. Author manuscript; available in PMC 2020 Jan 10.

Published in final edited form as: Nature. 2019 Jul; 571(7765): 424–428. Published online 2019 Jul 10. doi: 10.1038/s41586-019-1374-1

PMCID:: PMC6662915

Article PDF–3.3M

Select item 533983212.

Cytoplasmic m⁶A reader YTHDF3 promotes mRNA translation

Ang Li, Yu-Sheng Chen, Xiao-Li Ping, Xin Yang, Wen Xiao, Ying Yang, Hui-Ying Sun, Qin Zhu, Poonam Baidya, Xing Wang, Devi Prasad Bhattarai, Yong-Liang Zhao, Bao-Fa Sun, Yun-Gui Yang

Cell Res. 2017 Mar; 27(3): 444–447. Published online 2017 Jan 20. doi: 10.1038/cr.2017.10

PMCID:: PMC5339832

Article PDF–2.5M

Select item 496145913.

N⁶-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression

Nagaraja Tirumuru, Boxuan Simen Zhao, Wuxun Lu, Zhike Lu, Chuan He, Li Wu

eLife. 2016; 5: e15528. Published online 2016 Jul 2. doi: 10.7554/eLife.15528

Correction in:: eLife. 2017; 6: e31482.

PMCID:: PMC4961459

Article PDF–1.4M

Select item 533983414.

YTHDF3 facilitates translation and decay of N⁶-methyladenosine-modified RNA

Hailing Shi, Xiao Wang, Zhike Lu, Boxuan S Zhao, Honghui Ma, Phillip J Hsu, Chang Liu, Chuan He

Cell Res. 2017 Mar; 27(3): 315–328. Published online 2017 Jan 20. doi: 10.1038/cr.2017.15

PMCID:: PMC5339834

Article PDF–3.0M

Select item 303957015.

Initial characterization of the human central proteome

Thomas R Burkard, Melanie Planyavsky, Ines Kaupe, Florian P Breitwieser, Tilmann Bürckstümmer, Keiryn L Bennett, Giulio Superti-Furga, Jacques Colinge

BMC Syst Biol. 2011; 5: 17. Published online 2011 Jan 26. doi: 10.1186/1752-0509-5-17

PMCID:: PMC3039570

Article PDF–2.3M

Select item 387771516.

m⁶A-dependent regulation of messenger RNA stability

Xiao Wang, Zhike Lu, Adrian Gomez, Gary C. Hon, Yanan Yue, Dali Han, Ye Fu, Marc Parisien, Qing Dai, Guifang Jia, Bing Ren, Tao Pan, Chuan He

Nature. Author manuscript; available in PMC 2014 Jul 2.

Published in final edited form as: Nature. 2014 Jan 2; 505(7481): 117–120. Published online 2013 Nov 27. doi: 10.1038/nature12730

PMCID:: PMC3877715

Article PDF–1.2M

Select item 679484117.

Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m⁶A reader YTHDF3

Wen Ni, Su Yao, Yunxia Zhou, Yuanyuan Liu, Piao Huang, Aijun Zhou, Jingwen Liu, Liheng Che, Jianming Li

Mol Cancer. 2019; 18: 143. Published online 2019 Oct 16. doi: 10.1186/s12943-019-1079-y

PMCID:: PMC6794841

Article PDF–7.8M

Select item 250483518.

A quantitative atlas of mitotic phosphorylation

Noah Dephoure, Chunshui Zhou, Judit Villén, Sean A. Beausoleil, Corey E. Bakalarski, Stephen J. Elledge, Steven P. Gygi

Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31): 10762–10767. Published online 2008 Jul 31. doi: 10.1073/pnas.0805139105

PMCID:: PMC2504835

Article PDF–1.0M

Select item 865254019.

SARS‐CoV‐2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets

Syam Prakash Somasekharan, Martin Gleave

FEBS Lett. 2021 Dec; 595(23): 2872–2896. Published online 2021 Nov 22. doi: 10.1002/1873-3468.14229

PMCID:: PMC8652540

Article PDF–7.3M

Select item 713853720.

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

Johanna Hietamäki, Louise C Gregory, Sandy Ayoub, Anna-Pauliina Iivonen, Kirsi Vaaralahti, Xiaonan Liu, Nina Brandstack, Andrew J Buckton, Tiina Laine, Johanna Känsäkoski, Matti Hero, Päivi J Miettinen, Markku Varjosalo, Emma Wakeling, Mehul T Dattani, Taneli Raivio

J Clin Endocrinol Metab. 2020 Jun; 105(6): 1748–1758. Published online 2020 Feb 15. doi: 10.1210/clinem/dgaa078