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Select item 105783071.

A review on the relationship between Arachidonic acid 15-Lipoxygenase (ALOX15) and diabetes mellitus

Kaiying He, Xiaochun Zhou, Hongxuan Du, Jing Zhao, Rongrong Deng, Jianqin Wang

PeerJ. 2023; 11: e16239. Published online 2023 Oct 13. doi: 10.7717/peerj.16239

PMCID:: PMC10578307

Article PDF–2.0M

Select item 87181532.

15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation

Tadao Nagasaki, Alexander J. Schuyler, Jinming Zhao, Svetlana N. Samovich, Kazuhiro Yamada, Yanhan Deng, Scott P. Ginebaugh, Stephanie A. Christenson, Prescott G. Woodruff, John V. Fahy, John B. Trudeau, Detcho Stoyanovsky, Anuradha Ray, Yulia Y. Tyurina, Valerian E. Kagan, Sally E. Wenzel

J Clin Invest. 2022 Jan 4; 132(1): e151685. Published online 2022 Jan 4. doi: 10.1172/JCI151685

PMCID:: PMC8718153

Article PDF–2.9M

Select item 79874653.

Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil

Lawrence Coppey, Alexander Obrosov, Hanna Shevalye, Eric Davidson, William Paradee, Mark A. Yorek

J Diabetes Res. 2021; 2021: 5564477. Published online 2021 Mar 15. doi: 10.1155/2021/5564477

PMCID:: PMC7987465

Article PDF–785K

Select item 60330674.

Pinosylvin exacerbates LPS-induced apoptosis via ALOX 15 upregulation in leukocytes

Ohseong Kwon, Youngsik Seo, Heonyong Park

BMB Rep. 2018 Jun; 51(6): 302–307. Published online 2018 Jun 30. doi: 10.5483/BMBRep.2018.51.6.024

PMCID:: PMC6033067

Article PDF–3.5M

Select item 57241785.

Proteomic Signature Reveals Modulation of Human Macrophage Polarization and Functions Under Differing Environmental Oxygen Conditions

Magali Court, Graciane Petre, Michèle EL Atifi, Arnaud Millet

Mol Cell Proteomics. 2017 Dec; 16(12): 2153–2168. Published online 2017 Sep 8. doi: 10.1074/mcp.RA117.000082

PMCID:: PMC5724178

Article PDF–2.9M

Select item 56826766.

Increased 15-lipoxygenase-1 expression in chondrocytes contributes to the pathogenesis of osteoarthritis

Kaizhe Chen, Yufei Yan, Changwei Li, Jun Yuan, Fei Wang, Ping Huang, Niandong Qian, Jin Qi, Hanbing Zhou, Qi Zhou, Lianfu Deng, Chuan He, Lei Guo

Cell Death Dis. 2017 Oct; 8(10): e3109. Published online 2017 Oct 12. doi: 10.1038/cddis.2017.511

PMCID:: PMC5682676

Article PDF–5.6M

Select item 56660337.

Lipoxygenase‐mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3

Ryosuke Shintoku, Yuta Takigawa, Keiichi Yamada, Chisato Kubota, Yuhei Yoshimoto, Toshiyuki Takeuchi, Ichiro Koshiishi, Seiji Torii

Cancer Sci. 2017 Nov; 108(11): 2187–2194. Published online 2017 Sep 15. doi: 10.1111/cas.13380

PMCID:: PMC5666033

Article PDF–838K

Select item 49949388.

The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation

Annika Lundqvist, Mikael Sandstedt, Joakim Sandstedt, Ruth Wickelgren, Göran I. Hansson, Anders Jeppsson, Lillemor Mattsson Hultén

PLoS One. 2016; 11(8): e0161629. Published online 2016 Aug 23. doi: 10.1371/journal.pone.0161629

PMCID:: PMC4994938

Article PDF–4.5M

Select item 49687059.

Evolutionary alteration of ALOX15 specificity optimizes the biosynthesis of antiinflammatory and proresolving lipoxins

Susan Adel, Felix Karst, Àngels González-Lafont, Mária Pekárová, Patricia Saura, Laura Masgrau, José M. Lluch, Sabine Stehling, Thomas Horn, Hartmut Kuhn, Dagmar Heydeck

Proc Natl Acad Sci U S A. 2016 Jul 26; 113(30): E4266–E4275. Published online 2016 Jul 13. doi: 10.1073/pnas.1604029113

Correction in:: Proc Natl Acad Sci U S A. 2016 Dec 6; 113(49): E8006.

Correction in:: Proc Natl Acad Sci U S A. 2016 Dec 6; 113(49): E8008.

PMCID:: PMC4968705

Article PDF–1.6M

Select item 415409810.

Adipose Tissue 12/15 Lipoxygenase Pathway in Human Obesity and Diabetes

David C. Lieb, Joshua J. Brotman, Margaret A. Hatcher, Myo S. Aye, Banumathi K. Cole, Bronson A. Haynes, Stephen D. Wohlgemuth, Mark A. Fontana, Hind Beydoun, Jerry L. Nadler, Anca D. Dobrian

J Clin Endocrinol Metab. 2014 Sep; 99(9): E1713–E1720. Published online 2014 Jun 23. doi: 10.1210/jc.2013-4461

PMCID:: PMC4154098

Article

Select item 410173811.

15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1α expression in human colon cancer cells

Yuanqing Wu, Fei Mao, Xiangsheng Zuo, Micheline J Moussalli, Elias Elias, Weiguo Xu, Imad Shureiqi

Cancer Med. 2014 Jun; 3(3): 472–484. Published online 2014 Mar 15. doi: 10.1002/cam4.222

PMCID:: PMC4101738

Article PDF–1.2M

Select item 401034412.

Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring

Yao-hua Ke, Wen-jin Xiao, Jin-wei He, Hao Zhang, Jin-bo Yu, Wei-wei Hu, Jie-mei Gu, Gao Gao, Hua Yue, Chun Wang, Yun-qiu Hu, Miao Li, Yu-juan Liu, Wen-zhen Fu, Zhen-lin Zhang

Acta Pharmacol Sin. 2012 Feb; 33(2): 201–207. Published online 2012 Feb 3. doi: 10.1038/aps.2011.167

PMCID:: PMC4010344

Article PDF–338K

Select item 386009513.

12/15-Lipoxygenase expression is increased in oligodendrocytes and microglia of periventricular leukomalacia

Robin L. Haynes, Klaus van Leyen

Dev Neurosci. Author manuscript; available in PMC 2014 Apr 20.

Published in final edited form as: Dev Neurosci. 2013; 35(0): 10.1159/000350230. Published online 2013 Apr 20. doi: 10.1159/000350230

PMCID:: PMC3860095

Article PDF–2.2M

Select item 384405414.

EFFECT OF HUMAN 15-LIPOXYGENASE-1 METABOLITES ON VASCULAR FUNCTION IN MOUSE MESENTERIC ARTERIES AND HEARTS

Tamas Kriska, Cody Cepura, Lawan Siangjong, Tina C. Wan, John A. Auchampach, Aviv Shaish, Dror Haratz, Ganesh Kumar, John R. Falck, Kathryn M. Gauthier, William B. Campbell

Prostaglandins Other Lipid Mediat. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Prostaglandins Other Lipid Mediat. 2013 Oct; 0: 10.1016/j.prostaglandins.2013.07.002. Published online 2013 Jul 16. doi: 10.1016/j.prostaglandins.2013.07.002

PMCID:: PMC3844054

Article PDF–1.1M

Select item 359456415.

Inducible Endothelium-Derived Hyperpolarizing Factor (iEDHF): Role of the 15-Lipoxygenase-EDHF Pathway

William B. Campbell, Kathryn M. Gauthier

J Cardiovasc Pharmacol. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: J Cardiovasc Pharmacol. 2013 Mar; 61(3): 176–187. doi: 10.1097/FJC.0b013e31828165db

PMCID:: PMC3594564

Article PDF–1.3M

Select item 353241116.

Transcriptional Regulation of 15-Lipoxygenase Expression by Histone H3 Lysine 4 Methylation/Demethylation

Cheng Liu, Dawei Xu, Hongya Han, Yidong Fan, Frida Schain, Zhonghua Xu, Hans-Erik Claesson, Magnus Björkholm, Jan Sjöberg

PLoS One. 2012; 7(12): e52703. Published online 2012 Dec 28. doi: 10.1371/journal.pone.0052703

PMCID:: PMC3532411

Article PDF–453K

Select item 326108117.

15-lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in?

Sun IL Lee, Xiangsheng Zuo, Imad Shureiqi

Cancer Metastasis Rev. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Cancer Metastasis Rev. 2011 Dec; 30(3-4): 481–491. doi: 10.1007/s10555-011-9321-0

PMCID:: PMC3261081

Article PDF–945K

Select item 323231018.

Mechanistic Contribution of Ubiquitous 15-Lipoxygenase-1 Expression Loss in Cancer Cells to Terminal Cell Differentiation Evasion

Micheline J. Moussalli, Yuanqing Wu, Xiangsheng Zuo, Xiu L. Yang, Ignacio Ivan Wistuba, Maria G. Raso, Jeffrey S. Morris, Jessica L. Bowser, John D. Minna, Reuben Lotan, Imad Shureiqi

Cancer Prev Res (Phila) Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Cancer Prev Res (Phila). 2011 Dec; 4(12): 1961–1972. Published online 2011 Aug 31. doi: 10.1158/1940-6207.CAPR-10-0280

PMCID:: PMC3232310

Article PDF–3.1M

Select item 306139519.

Monocyte 15-Lipoxygenase Gene Expression Requires ERK1/2 MAPK Activity

Ashish Bhattacharjee, Anny Mulya, Srabani Pal, Biswajit Roy, Gerald M. Feldman, Martha K. Cathcart

J Immunol. Author manuscript; available in PMC 2011 Mar 21.

Published in final edited form as: J Immunol. 2010 Nov 1; 185(9): 5211–5224. Published online 2010 Sep 22. doi: 10.4049/jimmunol.1000514

PMCID:: PMC3061395

Article PDF–2.2M

Select item 277773820.

A 4-Oxo-2(E)-Nonenal-Derived Glutathione-Adduct from 15-Lipoxygenase-1-Mediated Oxidation of Cytosolic and Esterified Arachidonic Acid

Peijuan Zhu, Wenying Jian, Ian A. Blair

Free Radic Biol Med. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Free Radic Biol Med. 2009 Oct 1; 47(7): 953–961. Published online 2009 Jul 2. doi: 10.1016/j.freeradbiomed.2009.06.035