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Select item 108470931.

Transcription factor ATMIN facilitates chemoresistance in nasopharyngeal carcinoma

Xue-Liang Fang, Qing-Jie Li, Jia-Yi Lin, Cheng-Long Huang, Sheng-Yan Huang, Xi-Rong Tan, Shi-Wei He, Xun-Hua Zhu, Jun-Yan Li, Sha Gong, Han Qiao, Ying-Qin Li, Na Liu, Jun Ma, Yin Zhao, Ling-Long Tang

Cell Death Dis. 2024 Feb; 15(2): 112. Published online 2024 Feb 6. doi: 10.1038/s41419-024-06496-x

PMCID:: PMC10847093

Article PDF–5.1M

Select item 67974982.

ATMIN is a tumor suppressor gene in lung adenocarcinoma

Hanna Foster, E. Josue Ruiz, Christopher Moore, Gordon W. Stamp, Emma L. Nye, Ningning Li, Yihang Pan, Yulong He, Julian Downward, Axel Behrens

Cancer Res. Author manuscript; available in PMC 2020 Apr 15.

Published in final edited form as: Cancer Res. 2019 Sep 3; 79(20): 5159–5166. Published online 2019 Sep 3. doi: 10.1158/0008-5472.CAN-19-0647

PMCID:: PMC6797498

Article PDF–1.5M

Select item 55769153.

ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress

Rui Liu, Ashleigh King, Nicolas C. Hoch, Catherine Chang, Gemma L. Kelly, Andrew J. Deans, Jörg Heierhorst

DNA Repair (Amst) 2017 Sep; 57: 29–34. doi: 10.1016/j.dnarep.2017.06.022

PMCID:: PMC5576915

Article

Select item 18947714.

ATMIN defines an NBS1-independent pathway of ATM signalling

Nnennaya Kanu, Axel Behrens

EMBO J. 2007 Jun 20; 26(12): 2933–2941. Published online 2007 May 24. doi: 10.1038/sj.emboj.7601733

PMCID:: PMC1894771

Article PDF–319K

Select item 83191805.

MicroRNA-361-5p slows down gliomas development through regulating UBR5 to elevate ATMIN protein expression

Jiaoying Jia, Zhu Ouyang, Ming Wang, Wenjia Ma, Min Liu, Mingming Zhang, Mengqiang Yu

Cell Death Dis. 2021 Aug; 12(8): 746. Published online 2021 Jul 28. doi: 10.1038/s41419-021-04010-1

PMCID:: PMC8319180

Article PDF–3.6M

Select item 47536856.

Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1

Katarzyna B. Leszczynska, Eva-Leonne Göttgens, Deborah Biasoli, Monica M. Olcina, Jonathan Ient, Selvakumar Anbalagan, Stephan Bernhardt, Amato J. Giaccia, Ester M. Hammond

Sci Rep. 2016; 6: 21698. Published online 2016 Feb 15. doi: 10.1038/srep21698

PMCID:: PMC4753685

Article PDF–1.0M

Select item 42519807.

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress

Luisa Schmidt, Marc Wiedner, Georgia Velimezi, Jana Prochazkova, Michel Owusu, Sabine Bauer, Joanna I. Loizou

DNA Repair (Amst) 2014 Dec; 24: 122–130. doi: 10.1016/j.dnarep.2014.09.001

PMCID:: PMC4251980

Article

Select item 63354408.

Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling

Taylor Richards, Kavindiya Modarage, Charlotte Dean, Aidan McCarthy-Boxer, Helen Hilton, Chris Esapa, Jill Norman, Patricia Wilson, Paraskevi Goggolidou

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1; 1865(2): 378–390. doi: 10.1016/j.bbadis.2018.11.003

PMCID:: PMC6335440

Article

Select item 48420109.

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

Nnennaya Kanu, Tianyi Zhang, Rebecca A. Burrell, Atanu Chakraborty, Janet Cronshaw, Clive Da Costa, Eva Grönroos, Helen N. Pemberton, Emma Anderton, Laure Gonzalez, Simone Sabbioneda, Helle D. Ulrich, Charles Swanton, Axel Behrens

Oncogene. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Oncogene. 2016 Jul 28; 35(30): 4009–4019. Published online 2015 Nov 9. doi: 10.1038/onc.2015.427

Correction in:: Oncogene. 2016 Jul 28; 35(30): 4020.

PMCID:: PMC4842010

Article PDF–2.0M

Select item 117314510.

ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage

Carolyn J McNees, Lindus A Conlan, Nora Tenis, Jörg Heierhorst

EMBO J. 2005 Jul 6; 24(13): 2447–2457. Published online 2005 Jun 2. doi: 10.1038/sj.emboj.7600704

PMCID:: PMC1173145

Article PDF–509K

Select item 414303611.

UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function

Tianyi Zhang, Janet Cronshaw, Nnennaya Kanu, Ambrosius P. Snijders, Axel Behrens

Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33): 12091–12096. Published online 2014 Aug 4. doi: 10.1073/pnas.1400230111

PMCID:: PMC4143036

Article PDF–1.4M

Select item 327097012.

ATM Substrate Chk2-interacting Zn²⁺ Finger (ASCIZ) Is a Bi-functional Transcriptional Activator and Feedback Sensor in the Regulation of Dynein Light Chain (DYNLL1) Expression

Sabine Jurado, Lindus A. Conlan, Emma K. Baker, Jane-Lee Ng, Nora Tenis, Nicolas C. Hoch, Kimberly Gleeson, Monique Smeets, David Izon, Jörg Heierhorst

J Biol Chem. 2012 Jan 27; 287(5): 3156–3164. Published online 2011 Dec 13. doi: 10.1074/jbc.M111.306019

PMCID:: PMC3270970

Article PDF–2.8M

Select item 295881713.

Dual Functions of ASCIZ in the DNA Base Damage Response and Pulmonary Organogenesis

Sabine Jurado, Ian Smyth, Bryce van Denderen, Nora Tenis, Andrew Hammet, Kimberly Hewitt, Jane-Lee Ng, Carolyn J. McNees, Sergei V. Kozlov, Hayato Oka, Masahiko Kobayashi, Lindus A. Conlan, Timothy J. Cole, Ken-ichi Yamamoto, Yoshihito Taniguchi, Shunichi Takeda, Martin F. Lavin, Jörg Heierhorst

PLoS Genet. 2010 Oct; 6(10): e1001170. Published online 2010 Oct 21. doi: 10.1371/journal.pgen.1001170

Correction in:: PLoS Genet. 2010 Nov; 6(11): 10.1371/annotation/bce92e15-60b4-493b-89de-28529386f4ac.

PMCID:: PMC2958817

Article PDF–17M

Select item 437763414.

Interactome of the negative regulator of nuclear import BRCA1-binding protein 2

Shadma Fatima, Kylie M. Wagstaff, Kate L. Loveland, David A. Jans

Sci Rep. 2015; 5: 9459. Published online 2015 Mar 30. doi: 10.1038/srep09459

PMCID:: PMC4377634

Article PDF–12M

Select item 282477515.

Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects

Zari Dastani, Päivi Pajukanta, Michel Marcil, Nicholas Rudzicz, Isabelle Ruel, Swneke D Bailey, Jenny C Lee, Mathieu Lemire, Janet Faith, Jill Platko, John Rioux, Thomas J Hudson, Daniel Gaudet, James C Engert, Jacques Genest

Eur J Hum Genet. 2010 Mar; 18(3): 342–347. Published online 2009 Oct 21. doi: 10.1038/ejhg.2009.157

PMCID:: PMC2824775

Article PDF–366K

Select item 643661616.

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repairto Maintain Endothelial Homeostasis

Caiyun G. Li, Cathal Mahon, Nathaly M. Sweeney, Erik Verschueren, Vivek Kantamani, Dan Li, Jan K. Hennigs, David P. Marciano, Isabel Diebold, Ossama Abu-Halawa, Matthew Elliott, Silin Sa, Feng Guo, Lingli Wang, Aiqin Cao, Christophe Guignabert, Julie Sollier, Nils P. Nickel, Mark Kaschwich, Karlene A. Cimprich, Marlene Rabinovitch

Cell Rep. Author manuscript; available in PMC 2019 Mar 27.

Published in final edited form as: Cell Rep. 2019 Jan 29; 26(5): 1333–1343.e7. doi: 10.1016/j.celrep.2019.01.013

PMCID:: PMC6436616

Article PDF–1.9M

Select item 262894617.

Global analysis of host-pathogen interactions that regulate early stage HIV-1 replication

Renate König, Yingyao Zhou, Daniel Elleder, Tracy L. Diamond, Ghislain M.C. Bonamy, Jeffrey T. Irelan, Chih-yuan Chiang, Buu P. Tu, Paul D. De Jesus, Caroline E. Lilley, Shannon Seidel, Amanda M. Opaluch, Jeremy S. Caldwell, Matthew D. Weitzman, Kelli L. Kuhen, Sourav Bandyopadhyay, Trey Ideker, Anthony P. Orth, Loren J. Miraglia, Frederic D. Bushman, John A. Young, Sumit K. Chanda

Cell. Author manuscript; available in PMC 2009 Oct 3.

Published in final edited form as: Cell. 2008 Oct 3; 135(1): 49–60. doi: 10.1016/j.cell.2008.07.032

PMCID:: PMC2628946

Article PDF–3.4M

Select item 926261418.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Article PDF–3.6M

Select item 756688119.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Article PDF–4.8M

Select item 549522520.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Article PDF–1.3M

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