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Select item 53182311.

Two novel loci, COBL and SLC10A2, for Alzheimer’s disease in African Americans

Jesse Mez, Jaeyoon Chung, Gyungah Jun, Joshua Kriegel, Alexandra P. Bourlas, Richard Sherva, Mark W. Logue, Lisa L. Barnes, David A. Bennett, Joseph D. Buxbaum, Goldie S. Byrd, Paul K. Crane, Nilüfer Ertekin-Taner, Denis Evans, M. Daniele Fallin, Tatiana Foroud, Alison Goate, Neill R. Graff-Radford, Kathleen S. Hall, M. Ilyas Kamboh, Walter A. Kukull, Eric B. Larson, Jennifer J. Manly, Alzheimer’s Disease Genetics Consortium, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Kathryn L. Lunetta, Lindsay A. Farrer

Alzheimers Dement. Author manuscript; available in PMC 2017 Feb 20.

Published in final edited form as: Alzheimers Dement. 2017 Feb; 13(2): 119–129. Published online 2016 Oct 20. doi: 10.1016/j.jalz.2016.09.002

PMCID:: PMC5318231

Article PDF–963K

Select item 52881692.

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

Bruno Almeida Lopes, Claus Meyer, Thayana Conceição Barbosa, Udo zur Stadt, Martin Horstmann, Nicola C. Venn, Susan Heatley, Deborah L. White, Rosemary Sutton, Maria S. Pombo-de-Oliveira, Rolf Marschalek, Mariana Emerenciano

Oncotarget. 2016 Aug 16; 7(33): 53064–53073. Published online 2016 Jul 13. doi: 10.18632/oncotarget.10590

PMCID:: PMC5288169

Article PDF–2.5M

Select item 99649483.

COBL, MKX and MYOC Are Potential Regulators of Brown Adipose Tissue Development Associated with Obesity-Related Metabolic Dysfunction in Children

Sarah Abdul Majeed, Helene Dunzendorfer, Juliane Weiner, John T. Heiker, Wieland Kiess, Antje Körner, Kathrin Landgraf

Int J Mol Sci. 2023 Feb; 24(4): 3085. Published online 2023 Feb 4. doi: 10.3390/ijms24043085

PMCID:: PMC9964948

Article PDF–4.5M

Select item 45593584.

The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin

Wenya Hou, Maryam Izadi, Sabine Nemitz, Natja Haag, Michael M. Kessels, Britta Qualmann

PLoS Biol. 2015 Sep; 13(9): e1002233. Published online 2015 Sep 3. doi: 10.1371/journal.pbio.1002233

PMCID:: PMC4559358

Article PDF–14M

Select item 44719945.

Association of Granulomatosis With Polyangiitis (Wegener’s) With HLA–DPB1*04 and SEMA6A Gene Variants Evidence From Genome-Wide Analysis

Gang Xie, Delnaz Roshandel, Richard Sherva, Paul A. Monach, Emily Yue Lu, Tabitha Kung, Keisha Carrington, Steven S. Zhang, Sara L. Pulit, Stephan Ripke, Simon Carette, Paul F. Dellaripa, Jeffrey C. Edberg, Gary S. Hoffman, Nader Khalidi, Carol A. Langford, Alfred D. Mahr, E. William St.Clair, Philip Seo, Ulrich Specks, Robert F. Spiera, John H. Stone, Steven R. Ytterberg, Soumya Raychaudhuri, Paul I. W. de Bakker, Lindsay A. Farrer, Christopher I. Amos, Peter A. Merkel, Katherine A. Siminovitch

Arthritis Rheum. Author manuscript; available in PMC 2015 Jun 18.

Published in final edited form as: Arthritis Rheum. 2013 Sep; 65(9): 2457–2468. doi: 10.1002/art.38036

PMCID:: PMC4471994

Article PDF–1.0M

Select item 38101486.

Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder

Pingxing Xie, Henry R. Kranzler, Can Yang, Hongyu Zhao, Lindsay A. Farrer, Joel Gelernter

Biol Psychiatry. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Biol Psychiatry. 2013 Nov 1; 74(9): 10.1016/j.biopsych.2013.04.013. Published online 2013 May 28. doi: 10.1016/j.biopsych.2013.04.013

PMCID:: PMC3810148

Article PDF–319K

Select item 28890147.

Genome-wide association study and meta-analysis finds over 40 loci affect risk of type 1 diabetes

Jeffrey C. Barrett, David Clayton, Patrick Concannon, Beena Akolkar, Jason D. Cooper, Henry A. Erlich, Cécile Julier, Grant Morahan, Jørn Nerup, Concepcion Nierras, Vincent Plagnol, Flemming Pociot, Helen Schuilenburg, Deborah J. Smyth, Helen Stevens, John A. Todd, Neil M. Walker, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium

Nat Genet. Author manuscript; available in PMC 2010 Sep 21.

Published in final edited form as: Nat Genet. 2009 Jun; 41(6): 703–707. Published online 2009 May 10. doi: 10.1038/ng.381

PMCID:: PMC2889014

Article PDF–458K

Select item 66941328.

HENA, heterogeneous network-based data set for Alzheimer’s disease

Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson

Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0

PMCID:: PMC6694132

Article PDF–2.8M

Select item 99901209.

Interactomes of Glycogen Synthase Kinase-3 Isoforms

Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett

J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825

PMCID:: PMC9990120

Article PDF–3.7M

Select item 827099910.

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis

Rui Liu, Lin-Wen Zeng, Rong Gong, Fanen Yuan, Hong-Bing Shu, Shu Li

Nat Commun. 2021; 12: 4227. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24321-3

PMCID:: PMC8270999

Article PDF–3.8M

Select item 849099711.

BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters

Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen

EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136

PMCID:: PMC8490997

Article PDF–4.5M

Select item 394683712.

PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry

Alexandre Maréchal, Ju-Mei Li, Xiao Ye Ji, Ching-Shyi Wu, Stephanie A. Yazinski, Hai Dang Nguyen, Shizhou Liu, Amanda E. Jiménez, Jianping Jin, Lee Zou

Mol Cell. Author manuscript; available in PMC 2015 Jan 23.

Published in final edited form as: Mol Cell. 2014 Jan 23; 53(2): 235–246. Published online 2013 Dec 12. doi: 10.1016/j.molcel.2013.11.002

PMCID:: PMC3946837

Article PDF–2.0M

Select item 737208113.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Article PDF–2.0M

Select item 296748914.

A Human MAP Kinase Interactome

Sourav Bandyopadhyay, Chih-yuan Chiang, Jyoti Srivastava, Merril Gersten, Suhaila White, Russell Bell, Cornelia Kurschner, Christopher H. Martin, Mike Smoot, Sudhir Sahasrabudhe, Diane L. Barber, Sumit K. Chanda, Trey Ideker

Nat Methods. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: Nat Methods. 2010 Oct; 7(10): 801–805. doi: 10.1038/nmeth.1506

PMCID:: PMC2967489

Article PDF–1.2M

Select item 992246815.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Article PDF–4.9M

Select item 316943216.

Protein interactome reveals converging molecular pathways among autism disorders

Yasunari Sakai, Chad A. Shaw, Brian C. Dawson, Diana V. Dugas, Zaina Al-Mohtaseb, David E. Hill, Huda Y. Zoghbi

Sci Transl Med. Author manuscript; available in PMC 2011 Dec 8.

Published in final edited form as: Sci Transl Med. 2011 Jun 8; 3(86): 86ra49. doi: 10.1126/scitranslmed.3002166

PMCID:: PMC3169432

Article PDF–6.0M

Select item 638658817.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Article PDF–1.7M

Select item 895155618.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Article PDF–4.4M

Select item 933831319.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Article PDF–2.8M

Select item 929024120.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Article PDF–8.2M

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