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Select item 110308191.

Reduced immune effector cell NKG2D expression and increased levels of soluble NKG2D ligands in multiple myeloma may not be causally linked

Marie von Lilienfeld-Toal, Susanne Frank, Christiane Leyendecker, Sylvia Feyler, Sarah Jarmin, Ruth Morgan, Axel Glasmacher, Angela Märten, Ingo G. H. Schmidt-Wolf, Peter Brossart, Gordon Cook

Cancer Immunol Immunother. 2010 Jun; 59(6): 829–839. Published online 2009 Dec 19. doi: 10.1007/s00262-009-0807-3

PMCID:: PMC11030819

Article PDF–482K

Select item 108959542.

Elevated levels of cell-free NKG2D-ligands modulate NKG2D surface expression and compromise NK cell function in severe COVID-19 disease

Daniel Fernández-Soto, Álvaro F. García-Jiménez, José M. Casasnovas, Mar Valés-Gómez, Hugh T. Reyburn

Front Immunol. 2024; 15: 1273942. Published online 2024 Feb 12. doi: 10.3389/fimmu.2024.1273942

PMCID:: PMC10895954

Article PDF–2.6M

Select item 107041973.

Autophagy-mediated NKG2D internalization impairs NK cell function and exacerbates radiation pneumonitis

Ruiqing Wang, Xinyue Ma, Xinyu Zhang, Dizhi Jiang, Hongyuan Mao, Zerun Li, Yu Tian, Bo Cheng

Front Immunol. 2023; 14: 1250920. Published online 2023 Nov 24. doi: 10.3389/fimmu.2023.1250920

PMCID:: PMC10704197

Article PDF–7.5M

Select item 105184694.

Reovirus infection of tumor cells reduces the expression of NKG2D ligands, leading to impaired NK-cell cytotoxicity and functionality

Raghad Khaleafi, Jelena Zeleznjak, Sapir Cordela, Shani Drucker, Tihana Lenac Rovis, Stipan Jonjic, Yotam Bar-On

Front Immunol. 2023; 14: 1231782. Published online 2023 Sep 11. doi: 10.3389/fimmu.2023.1231782

PMCID:: PMC10518469

Article PDF–4.3M

Select item 104709085.

NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis

Laís A. Sacramento, Camila Farias Amorim, Taís M. Campos, Maíra Saldanha, Sérgio Arruda, Lucas P. Carvalho, Daniel P. Beiting, Edgar M. Carvalho, Fernanda O. Novais, Phillip Scott

PLoS Negl Trop Dis. 2023 Aug; 17(8): e0011552. Published online 2023 Aug 21. doi: 10.1371/journal.pntd.0011552

PMCID:: PMC10470908

Article PDF–1.5M

Select item 104196696.

Involvement of KLRK1 in immune infiltration of head and neck squamous cell carcinoma correlates with favorable prognosis

Haosheng Tan, Huaiyu Yang, Jiaxin Qian, Shaoyan Liu, Dangui Yan, Liyuan Wei, Wensheng Liu

Medicine (Baltimore) 2023 Aug 11; 102(32): e34761. Published online 2023 Aug 11. doi: 10.1097/MD.0000000000034761

PMCID:: PMC10419669

Article PDF–3.1M

Select item 103002937.

Role of NKG2D ligands and receptor in haploidentical related donor hematopoietic cell transplantation

Effie W. Petersdorf, Caroline McKallor, Mari Malkki, Meilun He, Stephen R. Spellman, Katharine C. Hsu, Roland K. Strong, Ted Gooley, Phil Stevenson

Blood Adv. 2023 Jun 27; 7(12): 2888–2896. Published online 2023 Feb 11. doi: 10.1182/bloodadvances.2022008922

PMCID:: PMC10300293

Article PDF–304K

Select item 99921618.

NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

Frederick J. Kohlhapp, Jeremy A. O’Sullivan, Tamson V. Moore, Andrew Zloza, José A. Guevara-Patiño

Mol Immunol. Author manuscript; available in PMC 2023 Mar 8.

Published in final edited form as: Mol Immunol. 2023 Mar; 155: 1–6. Published online 2023 Jan 10. doi: 10.1016/j.molimm.2022.12.013

PMCID:: PMC9992161

Article PDF–1.0M

Select item 98699739.

NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes

Daniel R. Calabrese, Tasha Tsao, Mélia Magnen, Colin Valet, Ying Gao, Beñat Mallavia, Jennifer J. Tian, Emily A. Aminian, Kristin M. Wang, Avishai Shemesh, Elman B. Punzalan, Aartik Sarma, Carolyn S. Calfee, Stephanie A. Christenson, Charles R. Langelier, Steven R. Hays, Jeffrey A. Golden, Lorriana E. Leard, Mary Ellen Kleinhenz, Nicholas A. Kolaitis, Rupal Shah, Aida Venado, Lewis L. Lanier, John R. Greenland, David M. Sayah, Abbas Ardehali, Jasleen Kukreja, S. Samuel Weigt, John A. Belperio, Jonathan P. Singer, Mark R. Looney

JCI Insight. 2022 Dec 22; 7(24): e164603. Published online 2022 Dec 22. doi: 10.1172/jci.insight.164603

PMCID:: PMC9869973

Article PDF–1.5M

Select item 882162210.

KLRK1 as a prognostic biomarker for lung adenocarcinoma cancer

Yanan Zhang, Zeyang Chen, Aifang Jiang, Guanqi Gao

Sci Rep. 2022; 12: 1976. Published online 2022 Feb 7. doi: 10.1038/s41598-022-05997-z

PMCID:: PMC8821622

Article PDF–2.4M

Select item 876257511.

NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes

Juan Fan, Jiawei Shi, Yong Zhang, Junwei Liu, Chenyi An, Huaying Zhu, Peng Wu, Wei Hu, Rui Qin, Danmei Yao, Xin Shou, Yibing Xu, Zhou Tong, Xue Wen, Jianpo Xu, Jin Zhang, Weijia Fang, Jizhong Lou, Weiwei Yin, Wei Chen

EMBO J. 2022 Jan 17; 41(2): e107739. Published online 2021 Dec 16. doi: 10.15252/embj.2021107739

PMCID:: PMC8762575

Article PDF–2.8M

Select item 829843212.

Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activation

Payal Dhar, Fahmin Basher, Zhe Ji, Lei Huang, Si Qin, Derek A. Wainwright, Jerid Robinson, Shaye Hagler, Jing Zhou, Sean MacKay, Jennifer D. Wu

Commun Biol. 2021; 4: 905. Published online 2021 Jul 22. doi: 10.1038/s42003-021-02440-3

PMCID:: PMC8298432

Article PDF–3.1M

Select item 804484513.

Role of Polymorphisms of NKG2D Receptor and Its Ligands in Acute Myeloid Leukemia and Human Stem Cell Transplantation

Alena Machuldova, Monika Holubova, Valentina S. Caputo, Miroslava Cedikova, Pavel Jindra, Lucie Houdova, Pavel Pitule

Front Immunol. 2021; 12: 651751. Published online 2021 Mar 30. doi: 10.3389/fimmu.2021.651751

PMCID:: PMC8044845

Article PDF–1.2M

Select item 798822814.

NKG2D as a Cell Surface Marker on γδ-T Cells for Predicting Pregnancy Outcomes in Patients With Unexplained Repeated Implantation Failure

Chunyu Huang, Zheng Xiang, Yongnu Zhang, Yuye Li, Jian Xu, Hongzhan Zhang, Yong Zeng, Wenwei Tu

Front Immunol. 2021; 12: 631077. Published online 2021 Mar 10. doi: 10.3389/fimmu.2021.631077

PMCID:: PMC7988228

Article PDF–1.1M

Select item 794435915.

Vogt–Koyanagi–Harada patients show higher frequencies of circulating NKG2D^pos NK and NK T cells

M. Bonacini, L. Cimino, L. De Simone, E. Bolletta, F. Gozzi, A. Soriano, F. Muratore, A. Zerbini, L. Fontana, C. Salvarani, S. Croci

Clin Exp Immunol. 2021 Apr; 204(1): 41–48. Published online 2020 Dec 27. doi: 10.1111/cei.13563

PMCID:: PMC7944359

Article PDF–439K

Select item 767188516.

Pseudomonas aeruginosa Infection Impairs NKG2D-Dependent NK Cell Cytotoxicity through Regulatory T-Cell Activation

Mickael Vourc’h, Gaelle David, Benjamin Gaborit, Alexis Broquet, Cedric Jacqueline, Tanguy Chaumette, Jocelyne Caillon, Antoine Roquilly, Christelle Retiere, Karim Asehnoune

Infect Immun. 2020 Dec; 88(12): e00363-20. Prepublished online 2020 Sep 14. Published online 2020 Nov 16. doi: 10.1128/IAI.00363-20

PMCID:: PMC7671885

Article PDF–2.4M

Select item 765723017.

Ataxia–telangiectasia mutated kinase‐mediated upregulation of NKG2D ligands on leukemia cells by resveratrol results in enhanced natural killer cell susceptibility

J. Luis Espinoza, Akiyoshi Takami, Ly Q. Trung, Shinji Nakao

Cancer Sci. 2013 Jun; 104(6): 657–662. Published online 2013 Apr 26. doi: 10.1111/cas.12141

PMCID:: PMC7657230

Article PDF–988K

Select item 698478718.

Dormancy and NKG2D system in brain metastases: Analysis of immunogenicity

Charlotte Flüh, Victor Mafael, Vivian Adamski, Michael Synowitz, Janka Held-Feindt

Int J Mol Med. 2020 Feb; 45(2): 298–314. Published online 2019 Dec 30. doi: 10.3892/ijmm.2019.4449

PMCID:: PMC6984787

Article PDF–1.7M

Select item 667317519.

NKG2D-Mediated Cytotoxicity toward Oligodendrocytes Suggests a Mechanism for Tissue Injury in Multiple Sclerosis

Philippe Saikali, Jack P. Antel, Jia Newcombe, Zhihong Chen, Mark Freedman, Manon Blain, Romain Cayrol, Alexandre Prat, Jeffery A. Hall, Nathalie Arbour

J Neurosci. 2007 Jan 31; 27(5): 1220–1228. doi: 10.1523/JNEUROSCI.4402-06.2007

PMCID:: PMC6673175

Article PDF–306K

Select item 616748320.

Higher Frequencies of Lymphocytes Expressing the Natural Killer Group 2D Receptor in Patients With Behçet Disease

Martina Bonacini, Alessandra Soriano, Alessandro Zerbini, Eleonora Calò, Luca Cimino, Francesco Muratore, Luigi Fontana, Luca Braglia, Maria Parmeggiani, Carlo Salvarani, Stefania Croci

Front Immunol. 2018; 9: 2157. Published online 2018 Sep 25. doi: 10.3389/fimmu.2018.02157

PMCID:: PMC6167483

Article PDF–6.9M

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