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Select item 107787001.

Mitogen-Activated Protein Kinase 15 Is a New Predictive Biomarker and Potential Therapeutic Target for Ovarian Cancer

Qiu-Hua Zhong, Andy T. Y. Lau, Yan-Ming Xu

Int J Mol Sci. 2024 Jan; 25(1): 109. Published online 2023 Dec 20. doi: 10.3390/ijms25010109

PMCID:: PMC10778700

Article PDF–1.6M

Select item 92828342.

MAPK15 protects from oxidative stress‐dependent cellular senescence by inducing the mitophagic process

Lorenzo Franci, Alessandro Tubita, Franca Maria Bertolino, Alessandro Palma, Giuseppe Cannino, Carmine Settembre, Andrea Rasola, Elisabetta Rovida, Mario Chiariello

Aging Cell. 2022 Jul; 21(7): e13620. Published online 2022 Jun 1. doi: 10.1111/acel.13620

PMCID:: PMC9282834

Article PDF–4.8M

Select item 61876253.

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process

David Colecchia, Francesca Dapporto, Serena Tronnolone, Laura Salvini, Mario Chiariello

J Biol Chem. 2018 Oct 12; 293(41): 15962–15976. Published online 2018 Aug 21. doi: 10.1074/jbc.RA118.002527

PMCID:: PMC6187625

Article PDF–4.8M

Select item 49915064.

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

Matteo Rossi, David Colecchia, Gennaro Ilardi, Mario Acunzo, Giovanni Nigita, Federica Sasdelli, Angela Celetti, Angela Strambi, Stefania Staibano, Carlo Maria Croce, Mario Chiariello

Oncotarget. 2016 Apr 12; 7(15): 20981–20998. Published online 2016 Mar 14. doi: 10.18632/oncotarget.8044

PMCID:: PMC4991506

Article PDF–9.0M

Select item 35434235.

Structure Prediction and Validation of the ERK8 Kinase Domain

Angela Strambi, Mattia Mori, Matteo Rossi, David Colecchia, Fabrizio Manetti, Francesca Carlomagno, Maurizio Botta, Mario Chiariello

PLoS One. 2013; 8(1): e52011. Published online 2013 Jan 11. doi: 10.1371/journal.pone.0052011

PMCID:: PMC3543423

Article PDF–1.6M

Select item 13860356.

Characterization of the reversible phosphorylation and activation of ERK8

Iva V. Klevernic, Margaret J. Stafford, Nicholas Morrice, Mark Peggie, Simon Morton, Philip Cohen

Biochem J. 2006 Feb 15; 394(Pt 1): 365–373. Prepublished online 2005 Dec 9. Published online 2006 Jan 27. doi: 10.1042/BJ20051288

PMCID:: PMC1386035

Article PDF–528K

Select item 46529977.

Overexpression of MAPK15 in gastric cancer is associated with copy number gain and contributes to the stability of c-Jun

Dong-Hao Jin, Jeeyun Lee, Kyoung Mee Kim, Sung Kim, Duk-Hwan Kim, Joobae Park

Oncotarget. 2015 Aug 21; 6(24): 20190–20203. Published online 2015 May 19. doi: 10.18632/oncotarget.4171

PMCID:: PMC4652997

Article PDF–2.8M

Select item 39455228.

ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration

Joanne Chia, Keit Min Tham, David James Gill, Emilie Anne Bard-Chapeau, Frederic A Bard

eLife. 2014; 3: e01828. Published online 2014 Mar 11. doi: 10.7554/eLife.01828

PMCID:: PMC3945522

Article PDF–4.8M

Select item 57144579.

Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells

Anna Kazatskaya, Stefanie Kuhns, Nils J. Lambacher, Julie E. Kennedy, Andrea G. Brear, Gavin J. McManus, Piali Sengupta, Oliver E. Blacque

Genetics. 2017 Dec; 207(4): 1423–1440. Published online 2017 Oct 10. doi: 10.1534/genetics.117.300383

PMCID:: PMC5714457

Article PDF–3.0M

Select item 482457210.

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

David Colecchia, Matteo Rossi, Federica Sasdelli, Sveva Sanzone, Angela Strambi, Mario Chiariello

Autophagy. 2015 Oct; 11(10): 1790–1802. Published online 2015 Aug 20. doi: 10.1080/15548627.2015.1084454

PMCID:: PMC4824572

Article PDF–1.3M

Select item 560747011.

The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism

Daniel P. Bermingham, J. Andrew Hardaway, Osama Refai, Christian R. Marks, Sam L. Snider, Sarah M. Sturgeon, William C. Spencer, Roger J. Colbran, David M. Miller, III, Randy D. Blakely

J Neurosci. 2017 Sep 20; 37(38): 9288–9304. doi: 10.1523/JNEUROSCI.1582-17.2017

PMCID:: PMC5607470

Article PDF–4.0M

Select item 292801312.

A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA

Angela L. Groehler, Deborah A. Lannigan

J Cell Biol. 2010 Aug 23; 190(4): 575–586. doi: 10.1083/jcb.201002124

PMCID:: PMC2928013

Article PDF–2.8M

Select item 481147113.

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

Urszula Liwak-Muir, Christine C. Dobson, Thet Naing, Quinlan Wylie, Lucia Chehade, Stephen D. Baird, Pranesh K. Chakraborty, Martin Holcik

Oncotarget. 2016 Jan 12; 7(2): 1439–1450. Published online 2015 Nov 22. doi: 10.18632/oncotarget.6363

PMCID:: PMC4811471

Article PDF–2.9M

Select item 304873414.

Extracellular Signal-regulated Kinase 8 (ERK8) Controls Estrogen-related Receptor α (ERRα) Cellular Localization and Inhibits Its Transcriptional Activity

Matteo Rossi, David Colecchia, Carlo Iavarone, Angela Strambi, Federica Piccioni, Arturo Verrotti di Pianella, Mario Chiariello

J Biol Chem. 2011 Mar 11; 286(10): 8507–8522. Published online 2010 Dec 28. doi: 10.1074/jbc.M110.179523

PMCID:: PMC3048734

Article PDF–3.8M

Select item 354128415.

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins

David Colecchia, Angela Strambi, Sveva Sanzone, Carlo Iavarone, Matteo Rossi, Claudia Dall’Armi, Federica Piccioni, Arturo Verrotti di Pianella, Mario Chiariello

Autophagy. 2012 Dec 1; 8(12): 1724–1740. doi: 10.4161/auto.21857

PMCID:: PMC3541284

Article PDF–4.2M

Select item 317378716.

ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association

Margarita Zacharogianni, Vangelis Kondylis, Yang Tang, Hesso Farhan, Despina Xanthakis, Florian Fuchs, Michael Boutros, Catherine Rabouille

EMBO J. 2011 Sep 14; 30(18): 3684–3700. Published online 2011 Aug 16. doi: 10.1038/emboj.2011.253

PMCID:: PMC3173787

Article PDF–2.7M

Select item 389478617.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Article PDF–5.0M

Select item 566346518.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004