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Items: 1 to 20 of 134

1.
KIF2C affects sperm cell differentiation in patients with Klinefelter syndrome, as revealed by RNA‐Seq and scRNA‐Seq data
Haihong He, Tingting Huang, Fan Yu, Keyan Chen, Shixing Guo, Lijun Zhang, Xi Tang, Xinhua Yuan, Jiao Liu, Yiwen Zhou
FEBS Open Bio. 2022 Aug; 12(8): 1465–1474. Published online 2022 Jun 16. doi: 10.1002/2211-5463.13446
PMCID:
PMC9340869
AbstractArticlePDF–2.3M
2.
Large-Scale Transcriptome Data Analysis Identifies KIF2C as a Potential Therapeutic Target Associated With Immune Infiltration in Prostate Cancer
Pingxin Zhang, Hang Gao, Chunwei Ye, Ruping Yan, Lu Yu, Chengxing Xia, Delin Yang
Front Immunol. 2022; 13: 905259. Published online 2022 Jun 3. doi: 10.3389/fimmu.2022.905259
PMCID:
PMC9203693
AbstractArticlePDF–14M
3.
Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration
Hailing Zong, Mark Hazelbaker, Christina Moe, Stephanie C. Ems-McClung, Ke Hu, Claire E. Walczak
Mol Biol Cell. 2021 Apr 1; 32(7): 590–604. doi: 10.1091/mbc.E20-05-0301
PMCID:
PMC8101467
AbstractArticlePDF–2.0M
4.
Functional characterization of MCAK/Kif2C cancer mutations using high-throughput microscopic analysis
Mike Wagenbach, Juan Jesus Vicente, Yulia Ovechkina, Sarah Domnitz, Linda Wordeman
Mol Biol Cell. 2020 Mar 19; 31(7): 580–588. doi: 10.1091/mbc.E19-09-0503
PMCID:
PMC7202071
AbstractArticlePDF–4.7M
5.
α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity
Luísa T. Ferreira, Bernardo Orr, Girish Rajendraprasad, António J. Pereira, Carolina Lemos, Joana T. Lima, Clàudia Guasch Boldú, Jorge G. Ferreira, Marin Barisic, Helder Maiato
J Cell Biol. 2020 Apr 6; 219(4): e201910064. Published online 2020 Feb 28. doi: 10.1083/jcb.201910064
PMCID:
PMC7147099
AbstractArticlePDF–7.9M
6.
Kinesin Kif2C in regulation of DNA double strand break dynamics and repair
Songli Zhu, Mohammadjavad Paydar, Feifei Wang, Yanqiu Li, Ling Wang, Benoit Barrette, Tadayoshi Bessho, Benjamin H Kwok, Aimin Peng
eLife. 2020; 9: e53402. Published online 2020 Jan 17. doi: 10.7554/eLife.53402
PMCID:
PMC7012618
AbstractArticlePDF–2.1M
7.
The Kinesin-Related Protein MCAK Is a Microtubule Depolymerase that Forms an ATP-Hydrolyzing Complex at Microtubule Ends
Andrew W. Hunter, Michael Caplow, David L. Coy, William O. Hancock, Stefan Diez, Linda Wordeman, Jonathon Howard
Mol Cell. Author manuscript; available in PMC 2019 Apr 17.
Published in final edited form as: Mol Cell. 2003 Feb; 11(2): 445–457. doi: 10.1016/s1097-2765(03)00049-2
PMCID:
PMC6468321
AbstractArticlePDF–879K
8.
MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility
Lauren D’Angelo, Nicole M. Myer, Kenneth A. Myers
Mol Biol Cell. 2017 May 1; 28(9): 1223–1237. doi: 10.1091/mbc.E16-05-0306
PMCID:
PMC5415018
AbstractArticlePDF–3.9M
9.
KIF-2C expression is correlated with poor prognosis of operable esophageal squamous cell carcinoma male patients
Hao Duan, Xu Zhang, Fei-Xiang Wang, Mu-Yan Cai, Guo-Wei Ma, Hong Yang, Jian-Hua Fu, Zi-Hui Tan, Xia-Yu Fu, Qi-Long Ma, Xin-Ye Wang, Peng Lin
Oncotarget. 2016 Dec 6; 7(49): 80493–80507. Published online 2016 Aug 22. doi: 10.18632/oncotarget.11492
PMCID:
PMC5348336
AbstractArticlePDF–3.6M
10.
The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition
Jennifer T. Patel, Hannah R. Belsham, Alexandra J. Rathbone, Bill Wickstead, Christopher Gell, Claire T. Friel
Open Biol. 2016 Oct; 6(10): 160223. Published online 2016 Oct 12. doi: 10.1098/rsob.160223
PMCID:
PMC5090061
AbstractArticlePDF–843K
11.
Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells
Andreas Ritter, Mourad Sanhaji, Alexandra Friemel, Susanne Roth, Udo Rolle, Frank Louwen, Juping Yuan
Cell Cycle. 2015; 14(23): 3755–3767. Published online 2015 Jul 6. doi: 10.1080/15384101.2015.1068481
PMCID:
PMC4825789
AbstractArticlePDF–1.2M
12.
New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C
Weiyi Wang, Ting Shen, Raphael Guerois, Fuming Zhang, Hureshitanmu Kuerban, Yuncong Lv, Benoît Gigant, Marcel Knossow, Chunguang Wang
J Biol Chem. 2015 Jul 24; 290(30): 18721–18731. Published online 2015 Jun 8. doi: 10.1074/jbc.M115.646919
PMCID:
PMC4513128
AbstractArticlePDF–2.1M
13.
Intracellular Targets for a Phosphotyrosine Peptidomimetic include the Mitotic Kinesin, MCAK
Rong Huang, Hyunju Oh, Allison Arrendale, Victoria A. Martin, Jacob Galan, Eric J. Workman, Jane R. Stout, Claire E. Walczak, W. Andy Tao, Richard F. Borch, Robert L. Geahlen
Biochem Pharmacol. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Biochem Pharmacol. 2013 Sep 1; 86(5): 597–611. Published online 2013 Jul 4. doi: 10.1016/j.bcp.2013.06.024
PMCID:
PMC3755495
AbstractArticlePDF–3.5M
14.
Control of MCAK Degradation and Removal from Centromeres
Anutosh Ganguly, Rajat Bhattacharya, Fernando Cabral
Cytoskeleton (Hoboken) Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Cytoskeleton (Hoboken). 2012 May; 69(5): 303–311. Published online 2012 Apr 3. doi: 10.1002/cm.21026
PMCID:
PMC3390786
AbstractArticlePDF–1.9M
15.
Kif2C Minimal Functional Domain Has Unusual Nucleotide Binding Properties That Are Adapted to Microtubule Depolymerization
Weiyi Wang, Qiyang Jiang, Manuela Argentini, David Cornu, Benoît Gigant, Marcel Knossow, Chunguang Wang
J Biol Chem. 2012 Apr 27; 287(18): 15143–15153. Published online 2012 Mar 8. doi: 10.1074/jbc.M111.317859
PMCID:
PMC3340219
AbstractArticlePDF–1.2M
16.
MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment
Sarah B. Domnitz, Michael Wagenbach, Justin Decarreau, Linda Wordeman
J Cell Biol. 2012 Apr 16; 197(2): 231–237. doi: 10.1083/jcb.201108147
PMCID:
PMC3328376
AbstractArticlePDF–1.8M
17.
Mitosis Phase Enrichment with Identification of Mitotic Centromere-Associated Kinesin As a Therapeutic Target in Castration-Resistant Prostate Cancer
Kanishka Sircar, Heng Huang, Limei Hu, Yuexin Liu, Jasreman Dhillon, David Cogdell, Armen Aprikian, Eleni Efstathiou, Nora Navone, Patricia Troncoso, Wei Zhang
PLoS One. 2012; 7(2): e31259. Published online 2012 Feb 17. doi: 10.1371/journal.pone.0031259
PMCID:
PMC3281954
AbstractArticlePDF–4.6M
18.
Overexpression of mitotic centromere associated kinesin stimulates microtubule detachment and confers resistance to paclitaxel
Anutosh Ganguly, Hailing Yang, Fernando Cabral
Mol Cancer Ther. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2011 Jun; 10(6): 929–937. Published online 2011 Apr 6. doi: 10.1158/1535-7163.MCT-10-1109
PMCID:
PMC3112244
AbstractArticlePDF–1.2M
19.
Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells
Swapna Kollu, Samuel F. Bakhoum, Duane A. Compton
Curr Biol. Author manuscript; available in PMC 2010 Dec 29.
Published in final edited form as: Curr Biol. 2009 Dec 29; 19(24): 2108–2113. doi: 10.1016/j.cub.2009.10.056
PMCID:
PMC2805786
AbstractArticlePDF–1.8M
20.
Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement
Anutosh Ganguly, Rajat Bhattacharya, Fernando Cabral
Cell Cycle. Author manuscript; available in PMC 2009 Oct 1.
Published in final edited form as: Cell Cycle. 2008 Oct; 7(20): 3187–3193. Published online 2008 Oct 18. doi: 10.4161/cc.7.20.6814
PMCID:
PMC2677962
AbstractArticlePDF–1.1M

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