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Induction of superoxide anion production in human monocytes assessed as increase in reduced cytochrome C level at 0.0025 to 1 uM incubated for 1 hr
Assay data:11 Tested
Summary
Modulation of COX-1 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Assay data:5 Tested
Modulation of LPS-induced IL-10 mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Assay data:1 Active, 5 Tested
Modulation of LPS-induced TNF-alpha mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Modulation of LPS-induced IL-1beta mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Modulation of LPS-induced IL-6 mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Induction of IL-10 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Induction of TNF-alpha mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Induction of IL-1beta mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Induction of IL-6 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Assay data:368 Active, 78 Activity ≤ 1 µM, 5114 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Assay data:158 Active, 29 Activity ≤ 1 µM, 5114 Tested
Primary qHTS for Vero E6 cytotoxicity: counterscreen for inhibitors of SARS-S pseudo-typed particle cell entry
Assay data:20 Active, 14 Activity ≤ 1 µM, 2678 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary qHTS for inhibitors of MERS-S pseudo-typed particle cell entry
Assay data:88 Active, 17 Activity ≤ 1 µM, 2678 Tested
Primary qHTS for Huh7 cytotoxicity: counterscreen for inhibitors of MERS-S pseudotyped particle cell entry
Assay data:25 Active, 8 Activity ≤ 1 µM, 2678 Tested
Primary cell-based high-throughput screening assay for identification of small molecule agonists of Aedes aegypti NPYLR7 [Small Molecule Inhibitors of Mosquito Biting Behavior]
Assay data:412 Active, 270665 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
Toxoplasma gondii HTS in the absence of IFN-y
Assay data:614 Active, 6425 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Toxoplasma gondii inhibition HTS in the presence of IFN-y
Assay data:2597 Active, 69085 Tested
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