BioAssays, activity concentration at/below 1 uM for PubChem Compound ( - PubChem BioAssay - NCBI

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Select item 19145711.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a TMEM97

Source:: ChEMBL

Protein Target:: Sigma intracellular receptor 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914571

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145702.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a SIGMAR1

Source:: ChEMBL

Protein Target:: Sigma non-opioid intracellular receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914570

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145653.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a DRD3

Source:: ChEMBL

Protein Target:: D(3) dopamine receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914565

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145634.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a ADRA2C

Source:: ChEMBL

Protein Target:: Alpha-2C adrenergic receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914563

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145625.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a ADRA2B

Source:: ChEMBL

Protein Target:: Alpha-2B adrenergic receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914562

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145616.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a ADRA2A

Source:: ChEMBL

Protein Target:: Alpha-2A adrenergic receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914561

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145607.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a HTR7

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 7

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914560

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145598.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a HTR2C

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2C

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914559

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19145589.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a HTR2B

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914558

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191455710.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a HTR2A

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914557

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191455611.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a HTR1D

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1D

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914556

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191455512.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000741a HTR1B

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914555

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179444713.

GPCRScan assay: inhibition of Sigma 1

Source:: ChEMBL

Protein Target:: Sigma non-opioid intracellular receptor 1

Assay data:20 Active, 13 Activity ≤ 1 µM, 181 Tested

AID:: 1794447

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179444614.

GPCRScan assay: inhibition of Sigma 2

Source:: ChEMBL

Protein Target:: Sigma intracellular receptor 2

Assay data:29 Active, 24 Activity ≤ 1 µM, 181 Tested

AID:: 1794446

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179443415.

GPCRScan assay: inhibition of Alpha2C

Source:: ChEMBL

Protein Target:: Alpha-2C adrenergic receptor

Assay data:7 Active, 7 Activity ≤ 1 µM, 181 Tested

AID:: 1794434

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179443316.

GPCRScan assay: inhibition of Alpha2B

Source:: ChEMBL

Protein Target:: Alpha-2B adrenergic receptor

Assay data:9 Active, 3 Activity ≤ 1 µM, 181 Tested

AID:: 1794433

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179443217.

GPCRScan assay: inhibition of Alpha2A

Source:: ChEMBL

Protein Target:: Alpha-2A adrenergic receptor

Assay data:6 Active, 3 Activity ≤ 1 µM, 181 Tested

AID:: 1794432

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179441618.

GPCRScan assay: inhibition of D3

Source:: ChEMBL

Protein Target:: D(3) dopamine receptor

Assay data:7 Active, 8 Activity ≤ 1 µM, 181 Tested

AID:: 1794416

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179441319.

GPCRScan assay: inhibition of 5-HT7A

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 7

Assay data:2 Active, 4 Activity ≤ 1 µM, 181 Tested

AID:: 1794413

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179440920.

GPCRScan assay: inhibition of 5-HT2C

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2C

Assay data:7 Active, 5 Activity ≤ 1 µM, 181 Tested

AID:: 1794409

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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BioActivity

Active Compounds (22)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (24)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (24)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Other (24)
BioAssays deposited by other experimentalists

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