Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Cytotoxicity activity against human HepG2 cells assessed by CellTiter-Glo luminescent cell viability assay.
Assay data:1241 Active, 184 Activity ≤ 1 µM, 1545 Tested
Summary
Inhibition of PMA-induced oxidative burst in human monocytes preincubated for 1 hr followed by PMA stimulation and measured after 30 mins
Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of PMA-induced oxidative burst in human monocytes at 0.1 to 50 nM preincubated for 1 hr followed by PMA stimulation and measured after 30 mins relative to control
Assay data:5 Tested
Induction of superoxide anion production in human monocytes assessed as increase in reduced cytochrome C level at 0.0025 to 1 uM incubated for 1 hr
Assay data:11 Tested
Inhibition of human COX-2 by spectrophotometer analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryRelated BioAssays by Target
Inhibition of human COX-1 by spectrophotometer analysis
Modulation of COX-1 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Modulation of LPS-induced IL-10 mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Assay data:1 Active, 5 Tested
Modulation of LPS-induced TNF-alpha mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Modulation of LPS-induced IL-1beta mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Modulation of LPS-induced IL-6 mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis
Downregulation of PMA-induced TNF-alpha mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by PMA stimulation and measured after 30 mins by RT-PCR analysis
Assay data:1 Active, 1 Tested
Inhibition of PMA-induced IL-1beta mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by PMA stimulation and measured after 30 mins by RT-PCR analysis
Induction of IL-10 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Induction of TNF-alpha mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Induction of IL-1beta mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Induction of IL-6 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis
Cytotoxicity against human monocytes assessed as reduction in cell viability at 0.01 to 10 uM incubated for 1 to 6 hrs by MTT assay
Antidepressant activity in ICR mouse assessed as reduction in immobility time at 40 mg/kg, po for 7 days by forced swimming test
Assay data:1 Tested
SummaryPubMed Citation
Binding affinity to human 5-HT7R assessed as inhibition constant
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on