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PIM1 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
PIM3 SGC Tm panel (DSF)
Inhibition of PIM1 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Inhibition of PIM1 (unknown origin) at 1 uM relative to control
Assay data:3 Tested
Inhibition of PIM1 (unknown origin) by Ambit kinase assay
Assay data:4 Tested
Inhibition of PIM1 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of PIM-1 (unknown origin)
Inhibition of human partial length wild type Pim-1 (M1/E291) expressed in bacterial system at 1 uM by KINOMEscan analysis relative to control
Inhibition of PIM1 (unknown origin) using poly-Glu-Tyr (4:1) as substrate in presence of [gamma-33P-ATP] incubated for 2 hrs by radiometric kinase assay
Assay data:1 Active, 2 Tested
Inhibition of full length human PIM1 expressed in Escherichia coli BL21 (DE3) preincubated for 0.5 hrs followed by substrate addition and measured after 0.5 hrs using ARKRRRHPSGPPTA and ATP as substrate by Glo-kinase assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of PIM3 (unknown origin)
Assay data:1 Active, 1 Tested
Binding affinity to human partial length Pim1 (A15 to K313 residues ) expressed in bacterial expression system by KdELECT kinase assay
Assay data:4 Active, 1 Activity ≤ 1 µM, 5 Tested
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