Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19629281.

MAP3K5 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1962928

Summary Related BioAssays by Target

Select item 19628242.

MAP3K5 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1962824

Summary Related BioAssays by Target

Select item 19627273.

MAP3K5 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1962727

Summary Related BioAssays by Target

Select item 19626284.

MAP3K5 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1962628

Summary Related BioAssays by Target

Select item 19348415.

Inhibition of human partial length wild type ASK1 expressed in bacterial system at 1 uM by KINOMEscan analysis relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1934841

Summary Related BioAssays by Target

Select item 19192326.

HTRF KinEASE Assay from US Patent US11560368: "Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase kinase kinase 5; ...
Total:: 1

Assay data:65 Active, 1 Activity ≤ 1 nM, 70 Activity ≤ 1 µM, 70 Tested

AID:: 1919232

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19141237.

Selectivity interaction (SelectScreen (Invitrogen)) EUB0000715a MAP3K5

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914123

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19138868.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000321b MAP3K5

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1913886

Summary Related BioAssays by Target

Select item 19138859.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000321b MAP3K5

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1913885

Summary Related BioAssays by Target

Select item 191345810.

Selectivity interaction (Kinase panel (enzymatic assay)) EUB0000153b MAP3K5

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1913458

Summary Related BioAssays by Target

Select item 191339211.

Selectivity interaction (Upstate Kinase Profiler service (Millipore)) EUB0000056c MAP3K5

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913392

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191255012.

Thermal Shift Assay. Domain: start/stop: R659-L951

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:27 Tested

AID:: 1912550

Summary Related BioAssays by Target

Select item 190154513.

Inhibition of recombinant human ASK1 (649 to 946 residues) assessed as residual activity at 1 uM using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric scintillation counting method

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1901545

Summary PubMed Citation Related BioAssays by Target

Select item 189404114.

Inhibition of ASK1 (unknown origin) in presence of ATP

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894041

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189404015.

Inhibition of ASK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894040

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 186044516.

Inhibition of ASK1 (unknown origin) at 0.5 uM relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1860445

Summary PubMed Citation Related BioAssays by Target

Select item 183561017.

ASK1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1835610

Summary Related BioAssays by Target

Select item 183528418.

MAP3K5 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1835284

Summary Related BioAssays by Target

Select item 183486619.

ASK1(h) Kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1834866

Summary Related BioAssays by Target

Select item 183403020.

Inhibition of ASK1 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 5

Assay data:1 Tested

AID:: 1834030

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (8)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (121)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (22)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (94)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (121)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (2)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (262)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (39)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (304)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1914123)
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PubChem BioAssay
RICTOR RPTOR independent companion of MTOR complex 2 [Homo sapiens]
RICTOR RPTOR independent companion of MTOR complex 2 [Homo sapiens]
Gene ID:253260

Gene
Gene Links for GEO Profiles (Select 121548030) (1)
Gene
Conserved Domain Links for Protein (Select 2217328313) (1)
Conserved Domains
LOC109461476 [Homo sapiens]
LOC109461476 [Homo sapiens]
Gene ID:109461476

Gene

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