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MAPKAPK2 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
MAPKAPK3 Invitrogen Lab (UK) kinase screen (BI)
MAPKAPK2 Invitrogen Lab (UK) kinase screen (BI)
Inhibition of MK2 (unknown origin) by Ambit kinase assay
Assay data:4 Tested
Inhibition of MK2 (unknown origin)
Inhibition of MAPKAPK2 (unknown origin)
Assay data:2 Activity ≤ 1 µM, 2 Tested
Inhibition of human partial length wild type MAPKAP-K2 expressed in bacterial system at 1 uM by KINOMEscan analysis relative to control
Inhibition of MAPKAP-K3 (unknown origin) at 25 nM relative to control
Assay data:6 Tested
Biochemical Assay from US Patent US11680056: "MK2 inhibitors and uses thereof"
Assay data:29 Active, 17 Activity ≤ 1 µM, 34 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (Enzyme panel (Invitrogen)) EUB0000730a MAPKAPK2
Assay data:1 Active, 1 Tested
Selectivity interaction (Kinase panel (University of Dundee)) EUB0000169b MAPKAPK2
Selectivity interaction (Enzymatic assay) EUB0000624a MAPKAPK2
Affinity Biochemical interaction (Enzymatic activity assay (Ustate kinase profiler Service; Millipore)) EUB0000056c MAPKAPK3
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Affinity Biochemical interaction (Enzymatic activity assay (Ustate kinase profiler Service; Millipore)) EUB0000056c MAPKAPK2
Affinity On-target Cellular interaction (Western Blot (phosphorylation of the MK2 substrate HSP27 in U937 cells)) EUB0000056c MAPKAPK2
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