Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19634651.

hERG Channel Activity from US Patent US11912693: "Compounds for modulating S1P1 activity and methods of using the same"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested

AID:: 1963465

Summary Related BioAssays by Target

Select item 19634552.

Experimental Evaluation of the In Vitro Inhibitory Effect (IC50) of hERG from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:15 Tested

AID:: 1963455

Summary Related BioAssays by Target

Select item 19631513.

Cross screening panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1963151

Summary Related BioAssays by Target

Select item 19630614.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1963061

Summary Related BioAssays by Target

Select item 19625695.

Potassium Channel hERG Eurofins Panlabs panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962569

Summary Related BioAssays by Target

Select item 19623846.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962384

Summary Related BioAssays by Target

Select item 19623357.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962335

Summary Related BioAssays by Target

Select item 19622368.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962236

Summary Related BioAssays by Target

Select item 19621909.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962190

Summary Related BioAssays by Target

Select item 196212510.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962125

Summary Related BioAssays by Target

Select item 196209411.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962094

Summary Related BioAssays by Target

Select item 196205012.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962050

Summary Related BioAssays by Target

Select item 196178513.

Compound was evaluated for inhibition of human KCNH2 in an in vitro assay with cellular components measured by membrane filtration, radioactivity method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:353 Active, 116 Activity ≤ 1 µM, 1804 Tested

AID:: 1961785

Summary Related BioAssays by Target

Select item 196157114.

Inhibition of human ERG

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Active, 1 Tested

AID:: 1961571

Summary Related BioAssays by Target

Select item 196126715.

Inhibition of hERG

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1961267

Summary Related BioAssays by Target

Select item 196070216.

Binding affinity to hERG (unknown origin)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1960702

Summary Related BioAssays by Target

Select item 196012717.

Inhibition of hERG

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1960127

Summary Related BioAssays by Target

Select item 196005618.

Inhibition of human ERG at 3 uM relative to control

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1960056

Summary Related BioAssays by Target

Select item 195750719.

Inhibition of human ERG

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1957507

Summary Related BioAssays by Target

Select item 195749520.

Displacement of [3H]dofetilide from human ERG expressed in CHO-K1 cell membrane measured after 45 mins by topcount scintillation counting method

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested

AID:: 1957495

Summary Related BioAssays by Target

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Proteins (34)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,591)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (27)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (718)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (2,598)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (8)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (4,107)
BioAssays extracted from the literature
NIH MLP (30)
BioAssays deposited by the NIH Molecular Libraries Program
Other (69)
BioAssays deposited by other experimentalists

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