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CDK2/Cyclin E1 Full length ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:95 Active, 92 Activity ≤ 1 µM, 97 Tested
SummaryRelated BioAssays by Target
CDK1/Cyclin B1 ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:75 Active, 1 Activity ≤ 1 nM, 52 Activity ≤ 1 µM, 99 Tested
Assay for Inhibition of CDK2/CyclinE1 from US Patent US20240033264: "CDK INHIBITORS"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
CDK2 SGC Tm panel (DSF)
Assay data:1 Tested
CDK2/CYCLINA Invitrogen Lab (UK) kinase screen (BI)
Inhibition of CDK2/cyclin A (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of CDK1/cyclin E (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of CDK1/cyclin B (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of GST-tagged human CDK2/Cyclin A2 expressed in baculovirus infected Sf9 cells using 5-FAM-QSPKKG-CONH2 as substrate at 10 uM incubated for 60 mins in presence of ATP relative to control
Inhibition of C-terminal His6 tagged human full length CDK1/N-terminal GST-tagged human full length Cyclin B expressed in baculovirus infected Sf21 cells using 5-FAM-QSPKKG-CONH2 as substrate at 10 uM incubated for 60 mins in presence of ATP relative to control
Inhibition of C-terminal His6 tagged human full length CDK1/N-terminal GST-tagged human full length Cyclin B expressed in baculovirus infected Sf21 cells using 5-FAM-QSPKKG-CONH2 as substrate incubated for 60 mins in presence of ATP
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of GST-tagged human CDK2/Cyclin A2 expressed in baculovirus infected Sf9 cells using 5-FAM-QSPKKG-CONH2 as substrate incubated for 60 mins in presence of ATP
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of CDK2/cyclin E1 (unknown origin) expressed in Sf9 cells
Assay data:2 Active, 9 Tested
Inhibition of CDK2/cyclin E (unknown origin)
Assay data:5 Active, 10 Tested
Inhibition of CDK2/cyclin A (unknown origin) at 1 uM relative to control
Assay data:3 Tested
Inhibition of CDK1 (unknown origin)
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