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Selectivity interaction (AlphaScreen assay) EUB0000214b MBTD1
Assay data:1 Tested
SummaryRelated BioAssays by Target
AlphaScreen Assay from Article 10.1021/cb500956g: "Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1."
Assay data:25 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Antagonist activity at MBTD1 (unknown origin) assessed as inhibition of MBTD1/biotinylated H4K20Me1 peptide interaction at 30 uM after 30 mins by AlphaScreen assay
Assay data:18 Tested
Antagonist activity at MBTD1 (unknown origin) assessed as inhibition of MBTD1/biotinylated H4K20Me1 peptide interaction after 30 mins by AlphaScreen assay
Assay data:2 Active, 24 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of MBTD1 (130 to 566) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay
SummaryPubMed CitationRelated BioAssays by Target
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay
Assay data:16 Active, 56 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to MBTD1 by chemiluminescent assay
Assay data:2 Tested
Inhibition of MBTD1 by alpha-screening
Assay data:19 Tested
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