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Inhibition Assay from US Patent US8952025: "Multifunctional radical quenchers and their uses"
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition Assay from Article 10.1021/bi8010362: "Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I)."
Assay data:19 Active, 1 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Bos taurus (bovine) heart submitochondrial NADH complex 1 by NADH oxidase assay
Assay data:7 Tested
SummaryRelated BioAssays by Target
Inhibition of Bos taurus (bovine) heart submitochondrial particle NDH1 assessed as NADH-DB reductase activity
Assay data:32 Active, 8 Activity ≤ 1 µM, 54 Tested
Inhibition of Bos taurus (beef) heart NAD1 assessed as NADH oxidase activity
Assay data:7 Active, 2 Activity ≤ 1 µM, 13 Tested
Inhibition of Bos taurus (beef) heart NAD1 assessed as NADH-ubiquinone oxidoreductase activity
Assay data:3 Active, 9 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Bos taurus (beef) heart NAD1
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Bos taurus (bovine) mitochondrial complex 1 assessed as reduction in enzyme activity by NADH-HU oxidoreductase assay
Assay data:9 Active, 7 Activity ≤ 1 µM, 10 Tested
Inhibition of Bos taurus (bovine) mitochondrial complex 1 assessed as reduction in enzyme activity by NADH-DU oxidoreductase assay
Assay data:8 Active, 6 Activity ≤ 1 µM, 8 Tested
Inhibition of Bos taurus (bovine) mitochodrial complex 1 isolated from heart submitochondrial particle by NADH oxidase assay
Assay data:6 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 13 Tested
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
Assay data:4 Active, 13 Tested
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation at 30 uM incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation at 30 uM incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay
Inhibition of bovine heart mitochondrial complex 1
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
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