BioAssay by Target (List) for Gene (Select 51701) - PubChem BioAssay - NCBI

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Select item 19142541.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000207b NLK

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914254

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19006132.

Inhibition of NLK (unknown origin) at 0.1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1900613

Summary PubMed Citation Related BioAssays by Target

Select item 18951343.

Inhibition of full length C-terminal nanoLuc-tagged human NLK expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of tracer K10 by NanoBRET assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Active, 1 Tested

AID:: 1895134

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18951234.

Inhibition of human NLK by radiometric PanQinase activity assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895123

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18951105.

Inhibition of human NLK at 1 uM by radiometric PanQinase activity assay relative to control (Rvb=50%)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1895110

Summary PubMed Citation Related BioAssays by Target

Select item 18646216.

Inhibition of human NLK at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1864621

Summary PubMed Citation Related BioAssays by Target

Select item 18355577.

NLK DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1835557

Summary Related BioAssays by Target

Select item 18350808.

NLK(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1835080

Summary Related BioAssays by Target

Select item 18342519.

Inhibition of NLK (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1834251

Summary PubMed Citation Related BioAssays by Target

Select item 179423310.

KinomeScan assay: inhibition of NLK

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:108 Tested

AID:: 1794233

Summary Related BioAssays by Target

Select item 179375611.

NLK(NLK1LGI5) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793756

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179346912.

NLK(NLK1LGI5) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793469

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179317513.

NLK(NLK1LGI5) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793175

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179278014.

NLK(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1792780

Summary Related BioAssays by Target

Select item 179239615.

NLK ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1792396

Summary Related BioAssays by Target

Select item 179110916.

NLK Kinase screen

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1791109

Summary Related BioAssays by Target

Select item 179028817.

NLK Invitrogen selectivity data (BI)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1790288

Summary Related BioAssays by Target

Select item 178938418.

NLK(h) Eurofins Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1789384

Summary Related BioAssays by Target

Select item 178906619.

NLK (h) Millipore kinase activity assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1789066

Summary Related BioAssays by Target

Select item 178743320.

NLK(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase NLK

Assay data:1 Tested

AID:: 1787433

Summary Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (20)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (18)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (24)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (63)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (118)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (67)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (92)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (90)
BioAssays deposited by other experimentalists

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