BioAssay by Target (List) for Gene (Select 5142) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 694

<< First< Prev

Page of 35

Select item 19192301.

Cytokine Assays from US Patent US11559538: "Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors"

Source:: BindingDB

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B; ...
Total:: 1

Assay data:149 Active, 42 Activity ≤ 1 nM, 149 Activity ≤ 1 µM, 149 Tested

AID:: 1919230

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19120392.

Inhibition of PDE4B2 (152 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 measured for 15 mins by liquid scintillation counter method

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912039

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19029353.

Inhibition of PDE4B2 (152 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1902935

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18979224.

Inhibition of full length human PDE4B using [3H]-cGMP as substrate at <5 uM incubated for 60 mins by microbeta scintillation counter analysis

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:1 Tested

AID:: 1897922

Summary PubMed Citation Related BioAssays by Target

Select item 18958435.

Inhibition of human PDE4 expressed in Sf9 cells by non-linear regression analysis

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895843

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18958426.

Inhibition of human recombinant PDE4B by liquid scintillation counter method

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1895842

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18843447.

Inhibition of PDE4B (unknown origin) using [3H]cAMP as substrate incubated for 1 hr by PDElight HTS cAMP phosphodiesterase assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1884344

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18715148.

Inhibition of PDE4 (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Active, 1 Tested

AID:: 1871514

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18592689.

Inhibition of cAMP-specific 3',5'-cyclic phosphodiesterase (unknown origin)

Source:: ChEMBL

Protein Targets:: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; ...
Total:: 23

Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 1859268

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185103910.

Inhibition of human PDE4 at 10 uM measured by radioligand binding assay relative to control

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1851039

Summary PubMed Citation Related BioAssays by Target

Select item 185051511.

Displacement of [3H]-cAMP from full-length recombinant human PDE4B2 by fluorescence polarisation assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1850515

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185051412.

Displacement of [3H]-cAMP from full-length recombinant human PDE4B1 by fluorescence polarisation assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1850514

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185051213.

Displacement of [3H]-cAMP from full-length recombinant human PDE4B2 catalytic domain by fluorescence polarisation assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1850512

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 181374114.

Inhibition of human PDE4 at 10 uM relative to control

Source:: ChEMBL

Protein Targets:: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; ...
Total:: 23

Assay data:1 Tested

AID:: 1813741

Summary PubMed Citation Related BioAssays by Target

Select item 181307815.

Inhibition of recombinant human PDE4 using histone H3 as substrate by ELISA-based assay

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1813078

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 181307616.

Inhibition of PDE4 (unknown origin) by in vitro screening assay

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Active, 1 Tested

AID:: 1813076

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 181307517.

Inhibition of PDE4 (unknown origin) by Fluopol-ABPP HTS assay

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1813075

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 181307418.

Inhibition of PDE4 (unknown origin) by colorimetric assay

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:4 Active, 3 Activity ≤ 1 µM, 6 Tested

AID:: 1813074

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 181307319.

Inhibition of PDE4 (unknown origin) in absence of calcium by colorimetric assay

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1813073

Summary PubMed Citation Related BioAssays by Target

Select item 181307220.

Inhibition of PDE4 (unknown origin) in presence of calcium by colorimetric assay

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1813072

Summary PubMed Citation Related BioAssays by Target

<< First< Prev

Page of 35

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (436)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (109)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (366)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (475)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (681)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (677)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (15)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 5142) (694)
PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay