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thallium-flux assay from US Patent US11632953: "Method for controlling hematophagous or sap-feeding arthropods"
Assay data:7 Active, 9 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of ROMK (unknown origin) by Thallium Efflux assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assay
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
Electrophysiology Assay from US Patent US10851108: "Substituted bicyclic heterocyclic compounds"
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibitory Activity Assay from US Patent US10759788: "Pharmaceutical uses of pyridine carboxamide derivatives"
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Electrophysiology Assay from US Patent US10723723: "Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors"
Assay data:30 Active, 1 Activity ≤ 1 nM, 30 Activity ≤ 1 µM, 30 Tested
Thallium Flux Assay from US Patent US10723723: "Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors"
Assay data:171 Active, 2 Activity ≤ 1 nM, 161 Activity ≤ 1 µM, 172 Tested
Thallium Flux Assay from US Patent US10513518: "Inhibitors of the renal outer medullary potassium channel"
Assay data:38 Active, 38 Activity ≤ 1 µM, 38 Tested
Electrophysiology Assay from US Patent US10501449: "Substituted nitrogen containing compounds"
Assay data:68 Active, 68 Activity ≤ 1 µM, 68 Tested
Biological Assay from US Patent US10364234: "Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof"
Electrophysiology Assay from US Patent US9493474: "Inhibitors of the renal outer medullary potassium channel"
Assay data:26 Active, 24 Activity ≤ 1 µM, 26 Tested
Thallium Flux Assay from US Patent US9493474: "Inhibitors of the renal outer medullary potassium channel"
Assay data:34 Active, 31 Activity ≤ 1 µM, 34 Tested
Electrophysiology Assay from US Patent US9206199: "Inhibitors of the renal outer medullary potassium channel"
Assay data:17 Active, 17 Activity ≤ 1 µM, 17 Tested
Thallium Flux Assay from US Patent US9206199: "Inhibitors of the renal outer medullary potassium channel"
Assay data:192 Active, 192 Activity ≤ 1 µM, 192 Tested
Electrophysiology Assay from US Patent US9206198: "Inhibitors of the renal outer medullary potassium channel"
Assay data:29 Active, 29 Activity ≤ 1 µM, 29 Tested
Thallium Flux Assay from US Patent US9206198: "Inhibitors of the renal outer medullary potassium channel"
Assay data:76 Active, 76 Activity ≤ 1 µM, 76 Tested
Electrophysiology Assay from US Patent US9139585: "Inhibitors of the Renal Outer Medullary Potassium channel"
Assay data:49 Active, 48 Activity ≤ 1 µM, 49 Tested
Thallium Flux Assay from US Patent US9073882: "Inhibitors of the renal outer medullary potassium channel"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Electrophysiology Assay from US Patent US9108947: "Inhibitors of the Renal Outer Medullary Potassium channel"
Assay data:17 Active, 13 Activity ≤ 1 µM, 17 Tested
Electrophysiology Assay from US Patent US9850245: "Inhibitors of the renal outer medullary potassium channel"
Assay data:21 Active, 21 Activity ≤ 1 µM, 21 Tested
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