Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assay
Assay data:17 Active, 4 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of human IAPP fibril formation assessed as decrease in final fluorescence intensity at compound/protein ratio of 10/1 by ThT fluorescence assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human IAPP fibril formation assessed as increase of aggregation half life at compound/protein ratio of 10/1 by ThT fluorescence assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Binding affinity to human IAPP fibril at 2 mM by saturation transfer difference NMR analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human IAPP fibril formation at 50 uM at 25 degC measured after 6 hrs by ThT fluorescence assay
Inhibition of human IAPP fibril formation at 50 uM at 25 degC measured after 6 hrs by atomic force microscopy
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of thioflavin T binding to human amylin assessed as half life
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Inhibition of IAPP assembly at 1:1 protein to compound ratio after 1 to 5 days by circular dichroism spectra analysis
Inhibition of IAPP assembly assessed as prenucleation period at 1:1 protein to compound ratio by NMR analysis
Inhibition of IAPP assembly at 1:1 protein to compound ratio after 29 days by NMR analysis
Inhibition of IAPP assembly assessed as nucleation period at 1:1 protein to compound ratio (Rvb = 15.3 days)
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on