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Inhibition of human recombinant GST-tagged CK-2 using RRRADDSDDDDD as substrate incubated for 5 mins by scintillation counter analysis
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human CK-2 at 10 uM by radiometric kinase activity assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human CK-2 at 0.1 uM by radiometric kinase activity assay relative to control
Inhibition of CK2 in HEK293 cells assessed as reduction in Akt phosphorylation at Ser129 residue at 10 to 50 uM by Western blot analysis
Inhibition of CK2 in human HeLa cells assessed as reduction in Akt phosphorylation at Ser129 residue at 10 to 50 uM by Western blot analysis
Inhibition of CK2 in HEK293 cells assessed as reduction in Akt phosphorylation at Ser129 residue incubated for 5 to 24 hrs by Western blot analysis
Inhibition of CK2 in human HeLa cells assessed as reduction in Akt phosphorylation at Ser129 residue incubated for 5 to 24 hrs by Western blot analysis
Inhibition of CK2 in human HL-60 cells assessed as increase in cleaved PARP level at 0.1 to 1 uM by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of CK2 in human HL-60 cells assessed as decrease in p-STAT3 level at 0.1 to 1 uM by Western blot analysis
Inhibition of CK2 in human HL-60 cells assessed as decrease in survivin level at 0.1 to 1 uM by Western blot analysis
Inhibition of CK2 in human HL-60 cells assessed as decrease in p-p21 level at 0.1 to 1 uM by Western blot analysis
Inhibition of CK2 in human HL-60 cells assessed as decrease in p-Akt (S129) level at 0.1 to 1 uM by Western blot analysis
Inhibition of CK2 in human HL-60 cells assessed as decrease in p-alpha-catenin level at 0.1 to 1 uM by Western blot analysis
Binding affinity to CK2 (unknown origin) by cellular thermal shift assay
Inhibition of CK2 (unknown origin)
Assay data:33 Active, 18 Activity ≤ 1 µM, 33 Tested
Inhibition of human recombinant CK2 at 10 uM using RRRDDDSDDD peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method
Assay data:22 Tested
Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method
Assay data:34 Active, 12 Activity ≤ 1 µM, 43 Tested
Inhibition of human CK2
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of CK2 in human MDA-MB-468 cells assessed as effect on CK2 protein level at 2.5 to 10 uM after 24 hrs by Western blot analysis
Inhibition of CK2 in human MDA-MB-231 cells assessed as effect on CK2 protein level at 2.5 to 10 uM after 24 hrs by Western blot analysis
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