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Intracellular Calcium Assay from US Patent US9346793: "Hydroxylated aminotriazole derivatives as ALX receptor agonists"
Assay data:15 Active, 15 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Fluorescence Laser Imaging Plate Reader (FLIPR) Based Assay from US Patent US9315518: "Imidazopyridin-2-one derivatives"
Assay data:25 Active, 23 Activity ≤ 1 µM, 25 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Biological Assay from US Patent US9278960: "Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use"
Assay data:288 Active, 286 Activity ≤ 1 µM, 290 Tested
FLIPR Assay from US Patent US9266876: "4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives"
Assay data:243 Active, 61 Activity ≤ 1 nM, 241 Activity ≤ 1 µM, 243 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 agonists (MedChem Round 1)
Assay data:11 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 antagonists (MedChem Round 1)
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 antagonists
Assay data:1 Active, 1 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for antagonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late state dose reponse assay to identify nonselective Ga16 agonists
Assay data:1 Active, 10 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 antagonists
Assay data:32 Tested
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based late stage dose response assay to identify nonselective Ga16 agonists
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Counterscreen for antagonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose reponse assay to identify nonselective Ga16 agonists
Assay data:40 Tested
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