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Measurement of c-Abl1, c-Abl2 and c-Kit IC50 Values from US Patent US11725005: "Compositions and methods for inhibiting kinases"
Assay data:43 Active, 43 Activity ≤ 1 µM, 43 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000686a ABL2
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (KiNativ profiling (A375 live cells treatment assays)) EUB0000238b ABL2
Inhibition of ABL2 (unknown origin) by Nano-syn mobility shift assay
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
ABL2 DiscoveRx kinase panel
Arg(h) Kinase panel
Inhibition of ABL2 (unknown origin) at 1 uM
Inhibition of ABL2 (unknown origin) at 1 uM relative to control
Kinase Assay from US Patent US10906896: "Compositions and methods for inhibiting kinases"
Assay data:42 Active, 42 Activity ≤ 1 µM, 42 Tested
Fluorescence Polarization Assay from Article 10.1074/jbc.M114.556480: "Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin."
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Kinase Inhibition Assays from US Patent US10266537: "3-acetylenyl-pyrazole-pyrimidine derivative, and preparation method therefor and uses thereof"
Assay data:27 Active, 4 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 27 Tested
KinomeScan assay: inhibition of ABL2
Assay data:108 Tested
Arg(ABL2LGF1) Takeda global kinase panel
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
Arg(h) Eurofins kinase panel
ABL2 ProQinase selectivity panel
ABL2 (Arg) Kinase screen
ABL2 Invitrogen selectivity data (BI)
Arg (h) Upstate kinase activity assay
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