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Inhibition of Cathepsin B (unknown origin) assessed as inhibition of AFC release using sequence RR labelled with AFC as substrate by fluorescence based analysis
Assay data:1 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human recombinant Cathepsin B using Z-Leu-Arg-AMC as substrate pretreated for 60 mins followed by substrate addition and incubated for 30 mins by microplate reader assay
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human liver cathepsin B at 100 uM using Boc-Leu-Arg-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by measuring amount of AMC formed by spectrofluorimetric method
Assay data:1 Tested
Inhibition of human liver cathepsin B using Boc-Leu-Arg-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by measuring amount of AMC formed by spectrofluorimetric method
Inhibition of recombinant human Cathepsin B expressed in human A549 using Z-Phe-Arg-AMC as substrate followed by CA-074 addition incubated for 30 mins by fluorometric assay
Inhibition of recombinant human Cathepsin B expressed in huamn A549 using Z-Phe-Arg-AMC as substrate incubated for 30 mins by fluorometric assay
Assay data:1 Active, 1 Tested
Inhibition of recombinant human Cathepsin B expressed in African green monkey Vero E6 using Z-Phe-Arg-AMC as substrate followed by CA-074 addition incubated for 30 mins by fluorometric assay
Inhibition of recombinant human Cathepsin B in African green monkey Vero E6 using Z-Phe-Arg-AMC as substrate for 30 mins by fluorometric assay
Inhibition of human recombinant Cathepsin B assessed as ratio of Kinact/Kiapp using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay
Assay data:5 Tested
Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant Cathepsin B assessed as Kinact using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay
Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 5 Tested
Inhibition of human cathepsin B incubated for 30 mins by fluorometric analysis
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of human cathepsin B at 1 uM incubated for 30 mins by fluorometric analysis
Assay data:7 Tested
Reversible inhibition of His-tagged recombinant human Cathepsin B expressed in HEK293 cells using Z-Leu-Arg-AMC as substrate at 120 nM incubated for 2.5 hrs followed by 100 fold dilution and incubated for 5 min and further incubated with substrate by fluorescence based analysis
Inhibition of His-tagged recombinant human Cathepsin B expressed in HEK293 cells using Z-Leu-Arg-AMC as substrate incubated for 30 mins followed by substrate addition by fluorescence based analysis
Inhibition of human cathepsin B using Z-Leu-Arg-AMC as substrate by FRET assay
Inhibition of human Cathepsin B assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to cathepsin B (unknown origin) at 1.875 to 50 uM by SPR assay
Assay data:2 Tested
Inhibition of human cathepsin B
Assay data:2 Active, 5 Tested
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