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Inhibition of N-terminal 6His-sumo-tagged recombinant human IP6K3 expressed in Escherichia coli assessed as inhibition of [3H]-InsP6 phosphorylation measured after 180 mins by HPLC analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of N-terminal 6His-sumo-tagged recombinant human IP6K3 expressed in Escherichia coli assessed as inhibition of [3H]-InsP6 phosphorylation at 10 nM measured after 180 mins by HPLC analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant full length human IP6K3 assessed as inorganic phosphate release measured after 2 hrs by ADP-Glo Max assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of N-terminal 6His-sumo-tagged recombinant human IP6K3 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as substrate in presence of ATP measured after 60 to 120 mins by malachite green based colorimetric - DIPP1 coupled enzyme assay
Assay data:31 Active, 13 Activity ≤ 1 µM, 37 Tested
Inhibition of IP6K3 (unknown origin) incubated for 120 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assay
Inhibition of IP6K3 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysis
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Primary screen of kinases in signalling pathway between Protease activated receptor 2 (PAR2) and the ion channels Transient receptor potential vanilloid-4 (TRPV4) in HEK293 cells
Assay data:91 Active, 714 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW620)
Assay data:15 Active, 794 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC5)
Assay data:11 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCT15)
Assay data:18 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (CAR1)
Assay data:9 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT55)
Assay data:20 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (RCM1)
Assay data:13 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT29)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC1)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (LS513)
Assay data:16 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (NCIH630)
Assay data:17 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCC56)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW48)
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